Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Surgical Endoscopy
Published in: Surgical Endoscopy 4/2011

01-04-2011

Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer

Authors: Xiaohua Jiang, Naoki Hiki, Souya Nunobe, Tetsu Fukunaga, Koshi Kumagai, Kyoko Nohara, Hiroshi Katayama, Shigekazu Ohyama, Takeshi Sano, Toshiharu Yamaguchi

Published in: Surgical Endoscopy | Issue 4/2011

Login to get access

Abstract

Background

Laparoscopically assisted pylorus-preserving gastrectomy (LAPPG) is introduced as a function-preserving operation with minimal invasion for early gastric cancer (EGC). This study aimed to investigate the long-term outcome and survival with LAPPG.

Methods

From January 2005 to July 2008, 188 patients with EGC underwent LAPPG. The surgical and long-term outcomes and survival were assessed retrospectively.

Results

The accuracy of the preoperative EGC diagnosis was 92.6%. The median follow-up period was 38 months (range, 2–63 months). Two patients experienced gallstones, and three patients experienced a second primary EGC. One patient with T3N0 gastric cancer died of peritoneal metastasis, and four patients died of other causes. The overall 3-year survival rate was 97.8%, and the disease-specific 3-year survival rate was 99.3%.

Conclusions

The LAPPG procedure is safe in terms of satisfactory long-term outcome and survival for patients with EGC in the middle third of the stomach.
Literature
1.
Maehara Y, Kakeji Y, Oda S, Takahashi I, Akazawa K, Sugimachi K (2000) Time trends of surgical treatment and the prognosis for Japanese patients with gastric cancer. Br J Cancer 83:986–991PubMedCrossRef
2.
Adachi Y, Mori M, Maehara Y, Kitano S, Sugimachi K (1997) Prognostic factors of node-negative gastric carcinoma: univariate and multivariate analyses. J Am Coll Surg 184:373–377PubMed
3.
Sano T, Hollowood A (2006) Early gastric cancer: diagnosis and less invasive treatments. Scand J Surg 95:249–255PubMed
4.
Shibata C, Shiiba KI, Funayama Y, Ishii S, Fukushima K, Mizoi T, Koyama K, Miura K, Matsuno S, Naito H, Kato E, Honda T, Momono S, Ouchi A, Ashino Y, Takahashi Y, Fujiya T, Iwatsuki A, Sasaki I (2004) Outcomes after pylorus-preserving gastrectomy for early gastric cancer: a prospective multicenter trial. World J Surg 28:857–861PubMedCrossRef
5.
Park do J, Lee HJ, Jung HC, Kim WH, Lee KU, Yang HK (2008) Clinical outcome of pylorus-preserving gastrectomy in gastric cancer in comparison with conventional distal gastrectomy with Billroth I anastomosis. World J Surg 32:1029–1036PubMedCrossRef
6.
Imada T, Rino Y, Takahashi M, Suzuki M, Tanaka J, Shiozawa M, Kabara K, Hatori S, Ito H, Yamamoto Y, Amano T (1998) Postoperative functional evaluation of pylorus-preserving gastrectomy for early gastric cancer compared with conventional distal gastrectomy. Surgery 123:165–170PubMedCrossRef
7.
Nunobe S, Sasako M, Saka M, Fukagawa T, Katai H, Sano T (2007) Symptom evaluation of long-term postoperative outcomes after pylorus-preserving gastrectomy for early gastric cancer. Gastric Cancer 10:167–172PubMedCrossRef
8.
Ohtani H, Tamamori Y, Noguchi K, Azuma T, Fujimoto S, Oba H, Aoki T, Minami M, Hirakawa K (2010) A meta-analysis of randomized controlled trials that compared laparoscopy-assisted and open distal gastrectomy for early gastric cancer. J Gastrointest Surg 14:958–964PubMedCrossRef
9.
Kitano S, Shiraishi N, Uyama I, Sugihara K, Tanigawa N (2007) A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Ann Surg 245:68–72PubMedCrossRef
10.
Kojima K, Yamada H, Inokuchi M, Kawano T, Sugihara K (2008) A comparison of Roux-en-Y and Billroth-I reconstruction after laparoscopy-assisted distal gastrectomy. Ann Surg 247:962–967PubMedCrossRef
11.
Hiki N, Shimoyama S, Yamaguchi H, Kubota K, Kaminishi M (2006) Laparoscopy-assisted pylorus-preserving gastrectomy with quality-controlled lymph node dissection in gastric cancer operation. J Am Coll Surg 203:162–169PubMedCrossRef
12.
Hiki N, Kaminishi M (2005) Pylorus-preserving gastrectomy in gastric cancer surgery: open and laparoscopic approaches. Langenbecks Arch Surg 390:442–447PubMedCrossRef
13.
Nunobe S, Hiki N, Fukunaga T, Tokunaga M, Ohyama S, Seto Y, Yamaguchi T (2007) Laparoscopy-assisted pylorus-preserving gastrectomy: preservation of vagus nerve and infrapyloric blood flow induces less stasis. World J Surg 31:2335–2340PubMedCrossRef
14.
Hiki N, Sano T, Fukunaga T, Ohyama S, Tokunaga M, Yamaguchi T (2009) Survival benefit of pylorus-preserving gastrectomy in early gastric cancer. J Am Coll Surg 209:297–301PubMedCrossRef
15.
Japanese Gastric Cancer A (1998) Japanese classification of gastric carcinoma. 2nd English ed. Gastric Cancer 1:10–24CrossRef
16.
Ryu KW, Kim YW, Lee JH, Nam BH, Kook MC, Choi IJ, Bae JM (2008) Surgical complications and the risk factors of laparoscopy-assisted distal gastrectomy in early gastric cancer. Ann Surg Oncol 15:1625–1631PubMedCrossRef
17.
Ikeguchi M, Hatada T, Yamamoto M, Miyake T, Matsunaga T, Fukuda K, Saito H, Tatebe S (2010) Evaluation of a pylorus-preserving gastrectomy for patients preoperatively diagnosed with early gastric cancer located in the middle third of the stomach. Surg Today 40:228–233PubMedCrossRef
18.
Horiuchi T, Shimomatsuya T, Chiba Y (2001) Laparoscopically assisted pylorus-preserving gastrectomy. Surg Endosc 15:325–328PubMedCrossRef
19.
Nakamura T, Onozato W, Mitomi H, Naito M, Sato T, Ozawa H, Hatate K, Ihara A, Watanabe M (2009) Retrospective, matched case-control study comparing the oncologic outcomes between laparoscopic surgery and open surgery in patients with right-sided colon cancer. Surg Today 39:1040–1045PubMedCrossRef
20.
Fukagawa T, Katai H, Saka M, Morita S, Sano T, Sasako M (2009) Gallstone formation after gastric cancer surgery. J Gastrointest Surg 13:886–889PubMedCrossRef
21.
Kojima K, Yamada H, Inokuchi M, Kawano T, Sugihara K (2008) Functional evaluation after vagus-nerve-sparing laparoscopically assisted distal gastrectomy. Surg Endosc 22:2003–2008PubMedCrossRef
22.
Naito H, Shibata C, Ohtani N, Funayama Y, Fukushima K, Matsuno S, Sasaki I (2002) Pylorus-preserving gastrectomy: effect on resistance through the sphincter of Oddi compared to conventional distal gastrectomy in dogs. World J Surg 26:602–607PubMedCrossRef
23.
Morita S, Katai H, Saka M, Fukagawa T, Sano T, Sasako M (2008) Outcome of pylorus-preserving gastrectomy for early gastric cancer. Br J Surg 95:1131–1135PubMedCrossRef
24.
Shimoyama S, Mafune K, Kaminishi M (2003) Indications for a pylorus-preserving gastrectomy for gastric cancer with proper muscle invasion. Arch Surg 138:1235–1239PubMedCrossRef
25.
Youn HG, An JY, Choi MG, Noh JH, Sohn TS, Kim S (2010) Recurrence after curative resection of early gastric cancer. Ann Surg Oncol 17:448–454PubMedCrossRef
Metadata
Title
Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer
Authors
Xiaohua Jiang
Naoki Hiki
Souya Nunobe
Tetsu Fukunaga
Koshi Kumagai
Kyoko Nohara
Hiroshi Katayama
Shigekazu Ohyama
Takeshi Sano
Toshiharu Yamaguchi
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 4/2011
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-010-1336-z

Other articles of this Issue 4/2011

Surgical Endoscopy 4/2011 Go to the issue

Dynamic Manuscript

Navigated renal access using electromagnetic tracking: an initial experience

Letter

Reply to: Laparoscopic sleeve gastrectomy: a retrospective review of 1- and 2-year results. Surg Endosc 2010 (24):781–785

OriginalPaper

Outcome of palliative self-expanding metal stent placement in malignant colorectal obstruction according to stent type and manufacturer

Letter--Reply

Importance of patient’s perceptions in developing new surgical techniques

OriginalPaper

Laparoscopic ileocecal resection for bowel endometriosis

OriginalPaper

Transvaginal laparoscopically assisted endoscopic cholecystectomy: preliminary clinical results for a series of 43 cases in China