Skip to main content
Top
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 2/2017

01-02-2017 | Knee

Long-term follow-up of isolated ACL tears treated without ligament reconstruction

Authors: Thomas L. Sanders, Ayoosh Pareek, Hilal Maradit Kremers, Andrew J. Bryan, Bruce A. Levy, Michael J. Stuart, Diane L. Dahm, Aaron J. Krych

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 2/2017

Login to get access

Abstract

Purpose

The incidence of subsequent meniscal tears and arthritis among patients with isolated ACL tears treated without ligament reconstruction has not been clearly established. The purpose of this study was to (1) compare the risk of subsequent meniscal tears and osteoarthritis (OA) between patients with isolated ACL tears treated without ligament reconstruction and a matched cohort of individuals without ACL tears and (2) examine factors predictive of long-term sequelae after non-operative treatment of isolated ACL tears.

Methods

This study compared a population-based incidence cohort of 364 patients with new-onset, isolated ACL tears between 1990 and 2000, to an age and sex-matched cohort of 364 individuals without ACL tears. A chart review was performed to collect information related to the initial injury, treatment, and outcomes. Subjects were retrospectively followed for mean follow-up of 14.3 years (±7.4 years) to determine the development of subsequent meniscal injury, arthritis, or total knee arthroplasty (TKA).

Results

Patients treated without ligament reconstruction after ACL tears had a significantly higher risk of secondary meniscal tears (HR 18.0, 95 % CI 9.7, 33.3), arthritis (HR 14.2, 95 % CI 8.0, 25.2), and need of TKA (HR 5.0, 95 % CI 2.1, 12.2) than individuals without ACL tears. Lateral meniscal tear at diagnosis was associated with a higher risk of arthritis (HR 2.7, 95 % CI 1.4, 5.7) and TKA (HR 4.3, 95 % CI 1.3, 13.7). Treatment with meniscectomy was associated with an increased risk of additional meniscal tears (HR 51.5, 95 % CI 10.3, 936.8).

Conclusions

Patients treated non-operatively after isolated ACL tears are at a significantly higher risk of secondary meniscal tears, arthritis, and TKA when compared to age and sex-matched subjects without ACL tears. Additionally, baseline lateral meniscal tears were significantly associated with an increased probability of developing arthritis and the need for TKA. This information may be helpful when counselling patients about the natural history of ACL tears treated without ligament reconstruction.

Level of evidence

III.
Literature
1.
go back to reference Ajuied A, Wong F, Smith C, Norris M, Earnshaw P, Back D, Davies A (2014) Anterior cruciate ligament injury and radiologic progression of knee osteoarthritis: a systematic review and meta-analysis. Am J Sports Med 42:2242–2252CrossRefPubMed Ajuied A, Wong F, Smith C, Norris M, Earnshaw P, Back D, Davies A (2014) Anterior cruciate ligament injury and radiologic progression of knee osteoarthritis: a systematic review and meta-analysis. Am J Sports Med 42:2242–2252CrossRefPubMed
2.
go back to reference Anstey D, Heyworth B, Price M, Gill T (2012) Effect of timing of ACL reconstruction in surgery and development of meniscal and chondral lesions. Phys Sportsmed 40:36–40CrossRefPubMed Anstey D, Heyworth B, Price M, Gill T (2012) Effect of timing of ACL reconstruction in surgery and development of meniscal and chondral lesions. Phys Sportsmed 40:36–40CrossRefPubMed
3.
go back to reference Baratz M, Fu F, Mengato R (1986) Meniscal tears: the effect of meniscectomy and repair on intraarticular contact areas and stress in the human knee. A preliminary report. Am J Sports Med 14:270–275CrossRefPubMed Baratz M, Fu F, Mengato R (1986) Meniscal tears: the effect of meniscectomy and repair on intraarticular contact areas and stress in the human knee. A preliminary report. Am J Sports Med 14:270–275CrossRefPubMed
4.
go back to reference Barbour K, Hootman J, Helmick C, Murphy L, Theis K, Schwartz T, Kalsbeek W, Renner J, Jordan J (2014) Meeting physical activity guidelines and the risk of incident knee osteoarthritis: a population-based prospective cohort study. Arthritis Care Res 66:139–146CrossRef Barbour K, Hootman J, Helmick C, Murphy L, Theis K, Schwartz T, Kalsbeek W, Renner J, Jordan J (2014) Meeting physical activity guidelines and the risk of incident knee osteoarthritis: a population-based prospective cohort study. Arthritis Care Res 66:139–146CrossRef
5.
go back to reference Barenius B, Ponzer S, Shalabi A, Bujak R, Norlen L, Eriksson K (2014) Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: a 14 year follow-up study of a randomized controlled trial. Am J Sports Med 42:1049–1057CrossRefPubMed Barenius B, Ponzer S, Shalabi A, Bujak R, Norlen L, Eriksson K (2014) Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: a 14 year follow-up study of a randomized controlled trial. Am J Sports Med 42:1049–1057CrossRefPubMed
6.
go back to reference Chalmers P, Mall N, Moric M, Sherman S, Paletta G, Cole B, Bach B (2014) Does ACL reconstruction alter natural history? A systematic literature review of long-term outcomes. J Bone Joint Surg Am 96:292–300CrossRefPubMed Chalmers P, Mall N, Moric M, Sherman S, Paletta G, Cole B, Bach B (2014) Does ACL reconstruction alter natural history? A systematic literature review of long-term outcomes. J Bone Joint Surg Am 96:292–300CrossRefPubMed
7.
go back to reference Culvenor A, Collins N, Guermazi A, Cook J, Vicenzino B, Khan K, Beck N, van Leeuwen J, Crossley K (2015) Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: a magnetic resonance imaging evaluation. Arthritis Rheumatol 67:946–955CrossRefPubMed Culvenor A, Collins N, Guermazi A, Cook J, Vicenzino B, Khan K, Beck N, van Leeuwen J, Crossley K (2015) Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: a magnetic resonance imaging evaluation. Arthritis Rheumatol 67:946–955CrossRefPubMed
8.
go back to reference Dejour H, Walch G, Deschamps G, Chambat P (2014) Arthrosis of the knee in chronic anterior laxity. Orthop Tramatol Surg Res 100:49–58CrossRef Dejour H, Walch G, Deschamps G, Chambat P (2014) Arthrosis of the knee in chronic anterior laxity. Orthop Tramatol Surg Res 100:49–58CrossRef
9.
go back to reference Dhillon K (2014) Doc’ do I need an anterior cruciate ligament reconstruction? What happens if I do not reconstruct the cruciate ligament? Malays Orthop J 8:42–47CrossRefPubMedPubMedCentral Dhillon K (2014) Doc’ do I need an anterior cruciate ligament reconstruction? What happens if I do not reconstruct the cruciate ligament? Malays Orthop J 8:42–47CrossRefPubMedPubMedCentral
10.
go back to reference Fok A, Yau W (2013) Delay in ACL reconstruction is associated with more severe and painful meniscal and chondral injuries. Knee Surg Sports Traumatol Arthrosc 21:928–993CrossRefPubMed Fok A, Yau W (2013) Delay in ACL reconstruction is associated with more severe and painful meniscal and chondral injuries. Knee Surg Sports Traumatol Arthrosc 21:928–993CrossRefPubMed
11.
go back to reference Frobell R, Roos E, Roos H, Ranstam J, Lohmander L (2010) A randomized trial of treatment for acute anterior cruciate ligament tears. N Engl J Med 363:331–342CrossRefPubMed Frobell R, Roos E, Roos H, Ranstam J, Lohmander L (2010) A randomized trial of treatment for acute anterior cruciate ligament tears. N Engl J Med 363:331–342CrossRefPubMed
12.
go back to reference Frobell R, Roos H, Roos E, Roemer F, Ranstam J, Lohmander L (2013) Treatment for acute anterior cruciate ligament tear: 5 year outcome of randomised trial. BMJ 346:f232CrossRefPubMedPubMedCentral Frobell R, Roos H, Roos E, Roemer F, Ranstam J, Lohmander L (2013) Treatment for acute anterior cruciate ligament tear: 5 year outcome of randomised trial. BMJ 346:f232CrossRefPubMedPubMedCentral
13.
go back to reference Hoffelner T, Resch H, Moroder P, Atzwanger J, Wiplinger M, Hitzl W, Tauber M (2012) No increased occurrence of osteoarthritis after anterior cruciate ligament reconstruction after isolated anterior cruciate ligament injury in athletes. Arthroscopy 28:517–525CrossRefPubMed Hoffelner T, Resch H, Moroder P, Atzwanger J, Wiplinger M, Hitzl W, Tauber M (2012) No increased occurrence of osteoarthritis after anterior cruciate ligament reconstruction after isolated anterior cruciate ligament injury in athletes. Arthroscopy 28:517–525CrossRefPubMed
14.
go back to reference Keene G, Bickerstaff D, Rae P, Paterson R (1993) The natural history of meniscal tears in anterior cruciate ligament insufficiency. Am J Sports Med 21:672–679CrossRefPubMed Keene G, Bickerstaff D, Rae P, Paterson R (1993) The natural history of meniscal tears in anterior cruciate ligament insufficiency. Am J Sports Med 21:672–679CrossRefPubMed
15.
go back to reference Kennedy J, Jackson M, O’Kelly P, Moran R (2010) Timing of reconstruction of the anterior cruciate ligament in athletes and the incidence of secondary pathology within the knee. J Bone Joint Surg Br 92:362–366CrossRefPubMed Kennedy J, Jackson M, O’Kelly P, Moran R (2010) Timing of reconstruction of the anterior cruciate ligament in athletes and the incidence of secondary pathology within the knee. J Bone Joint Surg Br 92:362–366CrossRefPubMed
16.
go back to reference Kessler M, Behrend H, Henz S, Stutz G, Rukavina A, Kuster M (2008) Function, osteoarthritis and activity after ACL-rupture: 11 years follow-up results of conservative versus reconstructive treatment. Knee Surg Sports Traumatol Arthrosc 16:442–448CrossRefPubMed Kessler M, Behrend H, Henz S, Stutz G, Rukavina A, Kuster M (2008) Function, osteoarthritis and activity after ACL-rupture: 11 years follow-up results of conservative versus reconstructive treatment. Knee Surg Sports Traumatol Arthrosc 16:442–448CrossRefPubMed
17.
go back to reference Leroux T, Ogilvie-Harris D, Dwyer T, Chahal J, Gandhi R, Mahomed N, Wasserstein D (2014) The risk of knee arthroplasty following cruciate ligament reconstruction: a population-based matched cohort study. J Bone Jt Surg Am 96:2–10CrossRef Leroux T, Ogilvie-Harris D, Dwyer T, Chahal J, Gandhi R, Mahomed N, Wasserstein D (2014) The risk of knee arthroplasty following cruciate ligament reconstruction: a population-based matched cohort study. J Bone Jt Surg Am 96:2–10CrossRef
18.
go back to reference Lohmander L, Englund P, Dahl L, Roos E (2007) The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med 35:1756–1769CrossRefPubMed Lohmander L, Englund P, Dahl L, Roos E (2007) The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med 35:1756–1769CrossRefPubMed
19.
go back to reference Michalitsis S, Vlychou M, Malizos K, Thriskos P, Hantes M (2013) Meniscal and articular cartilage lesions in the anterior cruciate ligament-deficient knee: correlation between time from injury and knee scores. Knee Surg Traumatol Arthrosc 23:232–239CrossRef Michalitsis S, Vlychou M, Malizos K, Thriskos P, Hantes M (2013) Meniscal and articular cartilage lesions in the anterior cruciate ligament-deficient knee: correlation between time from injury and knee scores. Knee Surg Traumatol Arthrosc 23:232–239CrossRef
20.
go back to reference Neuman P, Englund M, Kostohiannis I, Friden T, Roos H, Dahlberg L (2008) Prevalence of tibiofemoral osteoarthritis 15 years after nonoperative treatment of anterior cruciate ligament injury: a prospective cohort study. Am J Sports Med 36:1717–1725CrossRefPubMed Neuman P, Englund M, Kostohiannis I, Friden T, Roos H, Dahlberg L (2008) Prevalence of tibiofemoral osteoarthritis 15 years after nonoperative treatment of anterior cruciate ligament injury: a prospective cohort study. Am J Sports Med 36:1717–1725CrossRefPubMed
21.
go back to reference Øiestad B, Engebretsen L, Storheim K, Risberg M (2009) Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med 37:1434–1443CrossRefPubMed Øiestad B, Engebretsen L, Storheim K, Risberg M (2009) Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med 37:1434–1443CrossRefPubMed
22.
go back to reference Oiestad B, Holm L, Aune A, Gunderson R, Myklebust G, Engebretsen L, Fosdahl M, Risberg M (2010) Knee function and prevalence of knee osteoarthritis after anterior cruciate ligament reconstruction: a prospective study with 10–15 years of follow up. Am J Sports Med 38:2201–2210CrossRefPubMed Oiestad B, Holm L, Aune A, Gunderson R, Myklebust G, Engebretsen L, Fosdahl M, Risberg M (2010) Knee function and prevalence of knee osteoarthritis after anterior cruciate ligament reconstruction: a prospective study with 10–15 years of follow up. Am J Sports Med 38:2201–2210CrossRefPubMed
23.
go back to reference Papastergiou S, Koukoulias N, Mikalef P, Ziogas E, Voulgaropoulos H (2007) Meniscal tears in the ACL-deficient knee: correlation between meniscal tears and the timing of ACL reconstruction. Knee Surg Sports Traumatol Arthrosc 15:1438–1444CrossRefPubMed Papastergiou S, Koukoulias N, Mikalef P, Ziogas E, Voulgaropoulos H (2007) Meniscal tears in the ACL-deficient knee: correlation between meniscal tears and the timing of ACL reconstruction. Knee Surg Sports Traumatol Arthrosc 15:1438–1444CrossRefPubMed
24.
go back to reference Reid D, Leigh W, Wilkins S, Willis R, Twaddle B, Walsh S (2015) A 10-year retrospective review of functional outcomes of adolescent anterior cruciate ligament reconstruction. J Pediatr Orthop 0:1–5 Reid D, Leigh W, Wilkins S, Willis R, Twaddle B, Walsh S (2015) A 10-year retrospective review of functional outcomes of adolescent anterior cruciate ligament reconstruction. J Pediatr Orthop 0:1–5
25.
go back to reference Rocca W, Yawn B, St Sauver J, Grossardt B, Melton LJ (2012) History of the Rochester epidemiology project: half a century of medical records linkage in a US population. Mayo Clin Proc 87:1202–1213CrossRefPubMedPubMedCentral Rocca W, Yawn B, St Sauver J, Grossardt B, Melton LJ (2012) History of the Rochester epidemiology project: half a century of medical records linkage in a US population. Mayo Clin Proc 87:1202–1213CrossRefPubMedPubMedCentral
26.
go back to reference Shelbourne K, Gray T (2009) Minimum 10-year results after anterior cruciate ligament reconstruction: how the loss of normal knee motion compounds other factors related to the development of osteoarthritis after surgery. Am J Sports Med 37:471–480CrossRefPubMed Shelbourne K, Gray T (2009) Minimum 10-year results after anterior cruciate ligament reconstruction: how the loss of normal knee motion compounds other factors related to the development of osteoarthritis after surgery. Am J Sports Med 37:471–480CrossRefPubMed
27.
go back to reference St Sauver J, Grossardt B, Leibson C, Yawn B, Melton L, Rocca W (2012) Generalizability of epidemiological findings and public health decisions: an illustration from the Rochester epidemiology project. Mayo Clin Proc 87:151–160CrossRefPubMedPubMedCentral St Sauver J, Grossardt B, Leibson C, Yawn B, Melton L, Rocca W (2012) Generalizability of epidemiological findings and public health decisions: an illustration from the Rochester epidemiology project. Mayo Clin Proc 87:151–160CrossRefPubMedPubMedCentral
28.
go back to reference St Sauver J, Grossardt B, Yawn B et al (2012) Data resource profile: the Rochester epidemiology project (REP) medical records-linkage system. Int J Epidemiol 41:1614–1624CrossRefPubMedPubMedCentral St Sauver J, Grossardt B, Yawn B et al (2012) Data resource profile: the Rochester epidemiology project (REP) medical records-linkage system. Int J Epidemiol 41:1614–1624CrossRefPubMedPubMedCentral
29.
go back to reference St Sauver J, Grossardt B, Yawn B, Melton L, Rocca W (2011) Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester epidemiology project. Am J Epidemiol 173:1059–1068CrossRefPubMedPubMedCentral St Sauver J, Grossardt B, Yawn B, Melton L, Rocca W (2011) Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester epidemiology project. Am J Epidemiol 173:1059–1068CrossRefPubMedPubMedCentral
30.
go back to reference Widener D, Wilson D, Galvin J, Marchant B, Arrington E (2015) The prevalence of meniscal tears in young athletes undergoing revision anterior cruciate ligament reconstruction. Arthroscopy 31:680–683CrossRefPubMed Widener D, Wilson D, Galvin J, Marchant B, Arrington E (2015) The prevalence of meniscal tears in young athletes undergoing revision anterior cruciate ligament reconstruction. Arthroscopy 31:680–683CrossRefPubMed
Metadata
Title
Long-term follow-up of isolated ACL tears treated without ligament reconstruction
Authors
Thomas L. Sanders
Ayoosh Pareek
Hilal Maradit Kremers
Andrew J. Bryan
Bruce A. Levy
Michael J. Stuart
Diane L. Dahm
Aaron J. Krych
Publication date
01-02-2017
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 2/2017
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-016-4172-4

Other articles of this Issue 2/2017

Knee Surgery, Sports Traumatology, Arthroscopy 2/2017 Go to the issue