Localized Janeway lesions after ECMO

Excerpt

We report on a 60-year-old male patient with obesity who presented with severe pulmonary hypertension, severe mitral regurgitation and moderate tricuspid regurgitation, subsequently undergoing mitral valve replacement and tricuspid ring implantation. The surgical procedure required veno-arterial extracorporeal membrane oxygenation (ECMO), with cannulation of the left femoral vessels, due to cardiogenic shock resulting from right ventricle failure. The patient was weaned from ECMO on the fourth day. One month later he presented with fever and Janeway lesions on the sole of the left foot (Fig. 1a). Pseudomonas aeruginosa was detected in the blood culture and in the wound culture of the left groin. Transesophageal echocardiography did not show any sign of endocarditis. Echo Doppler and computed tomography scans showed pseudoaneurysm of the left femoral artery, which required open surgical repair (Fig. 1b, c). Culture of the pseudoaneurysm of the femoral artery, carried out after 4 weeks of antibiotic treatment with cefepime and ciprofloxacin, was negative. Microscopic examination showed inflammatory infiltrate with foreign-body giant cells.

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