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Journal of Assisted Reproduction and Genetics

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01-09-2018 | Commentary

Local privileges not universal rights: geographic variations in the science and clinical practice of reproductive medicine

Author: Alexander M. Quaas

Published in: Journal of Assisted Reproduction and Genetics | Issue 9/2018

Abstract

Based on personal experience in the science and clinical practice of reproductive medicine in different settings, enormous variations are highlighted, demonstrating that freedom of research and clinical practice in reproductive medicine is a local privilege, not a universal right.

Quaas AM, et al. Early markers of reprogramming in induced pluripotent stem cells (iPSCs): a timeline of key steps in the reprogramming process. Fertil Steril. 2011;95(4):S5.CrossRef

Pomeroy JE, Hough SR, Davidson KC, Quaas AM, Rees JA, Pera MF. Stem cell surface marker expression defines late stages of reprogramming to pluripotency in human fibroblasts. Stem Cells Transl Med. 2016;5(7):870–82.CrossRefPubMedPubMedCentral

Annas GJ. Resurrection of a stem-cell funding barrier—Dickey-Wicker in court. N Engl J Med. 2010;363(18):1687–9.CrossRefPubMed

Trounson A. California Institute for Regenerative Medicine: accelerating stem cell therapies in California and beyond. Stem Cells Transl Med. 2012;1(1):6–8.CrossRefPubMedPubMedCentral

Owen-Smith J, McCormick J. An international gap in human ES cell research. Nat Biotechnol. 2006;24(4):391–2.CrossRefPubMed

Guzick DS, Carson SA, Coutifaris C, Overstreet JW, Factor-Litvak P, Steinkampf MP, et al. Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network. N Engl J Med. 1999;340(3):177–83.CrossRefPubMed

Myers, E.R., Silva S., Barnhart K., Groben P.A., Richardson M.S., Robboy S.J., Leppert P., Coutifaris C., NICHD National Cooperative Reproductive Medicine Network., Interobserver and intraobserver variability in the histological dating of the endometrium in fertile and infertile women. Fertil Steril, 2004. 82(5): p. 1278–1282.

Legro, R.S., Barnhart H.X., Schlaff W.D., Carr B.R., Diamond M.P., Carson S.A., Steinkampf M.P., Coutifaris C., McGovern P., Cataldo N.A., Gosman G.G., Nestler J.E., Giudice L.C., Leppert P.C., Myers E.R., Cooperative Multicenter Reproductive Medicine Network., Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med, 2007. 356(6): p. 551–566.

Legro, R.S., Brzyski R.G., Diamond M.P., Coutifaris C., Schlaff W.D., Casson P., Christman G.M., Huang H., Yan Q., Alvero R., Haisenleder D.J., Barnhart K.T., Bates G.W., Usadi R., Lucidi S., Baker V., Trussell J.C., Krawetz S.A., Snyder P., Ohl D., Santoro N., Eisenberg E., Zhang H., NICHD Reproductive Medicine Network., Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med, 2014. 371(2): p. 119–129.

10.

Diamond, M.P., Legro R.S., Coutifaris C., Alvero R., Robinson R.D., Casson P., Christman G.M., Ager J., Huang H., Hansen K.R., Baker V., Usadi R., Seungdamrong A., Bates G.W., Rosen R.M., Haisenleder D., Krawetz S.A., Barnhart K., Trussell J.C., Ohl D., Jin Y., Santoro N., Eisenberg E., Zhang H., NICHD Reproductive Medicine Network., Letrozole, gonadotropin, or clomiphene for unexplained infertility. N Engl J Med, 2015. 373(13): p. 1230–1240.

11.

Israel R. Footfalls echo in the memory. Fertil Steril. 1982;38(4):403–5.CrossRefPubMed

12.

Diagnosis and Management of Ectopic Pregnancy: Green-top Guideline No. 21. BJOG, 2016. 123(13): p. e15–e55.

13.

Chambers GM, Sullivan EA, Ishihara O, Chapman MG, Adamson GD. The economic impact of assisted reproductive technology: a review of selected developed countries. Fertil Steril. 2009;91(6):2281–94.CrossRefPubMed

14.

Mavrelos D, Memtsa M, Helmy S, Derdelis G, Jauniaux E, Jurkovic D. Beta-hCG resolution times during expectant management of tubal ectopic pregnancies. BMC Womens Health. 2015;15:43.CrossRefPubMedPubMedCentral

15.

Cohen MA, Sauer MV. Expectant management of ectopic pregnancy. Clin Obstet Gynecol. 1999;42(1):48–54. quiz 55-6CrossRefPubMed

16.

Craig LB, Khan S. Expectant management of ectopic pregnancy. Clin Obstet Gynecol. 2012;55(2):461–70.CrossRefPubMed

17.

Parks MA, Barnhart KT, Howard DL. Trends in the management of nonviable pregnancies of unknown location in the United States. Gynecol Obstet Investig. 2018:1–6.

18.

van Mello NM, Mol F, Verhoeve HR, van Wely M, Adriaanse AH, Boss EA, et al. Methotrexate or expectant management in women with an ectopic pregnancy or pregnancy of unknown location and low serum hCG concentrations? A randomized comparison. Hum Reprod. 2013;28(1):60–7.CrossRefPubMed

19.

Kirk E, Bottomley C, Bourne T. Diagnosing ectopic pregnancy and current concepts in the management of pregnancy of unknown location. Hum Reprod Update. 2014;20(2):250–61.CrossRefPubMed

20.

Gordon CM. Clinical practice. Functional hypothalamic amenorrhea. N Engl J Med. 2010;363(4):365–71.CrossRefPubMed

21.

Schneider LF, Warren MP. Functional hypothalamic amenorrhea is associated with elevated ghrelin and disordered eating. Fertil Steril. 2006;86(6):1744–9.CrossRefPubMed

22.

Belchetz PE, et al. Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone. Science. 1978;202(4368):631–3.CrossRefPubMed

23.

Buchter D, Behre H, Kliesch S, Nieschlag E. Pulsatile GnRH or human chorionic gonadotropin/human menopausal gonadotropin as effective treatment for men with hypogonadotropic hypogonadism: a review of 42 cases. Eur J Endocrinol. 1998;139(3):298–303.CrossRefPubMed

24.

Christou F, Pitteloud N, Gomez F. The induction of ovulation by pulsatile administration of GnRH: an appropriate method in hypothalamic amenorrhea. Gynecol Endocrinol. 2017;33(8):598–601.CrossRefPubMed

25.

Hurley DM, Brian R, Outch K, Stockdale J, Fry A, Hackman C, et al. Induction of ovulation and fertility in amenorrheic women by pulsatile low-dose gonadotropin-releasing hormone. N Engl J Med. 1984;310(17):1069–74.CrossRefPubMed

26.

Martin KA, Hall JE, Adams JM, Crowley WF Jr. Comparison of exogenous gonadotropins and pulsatile gonadotropin-releasing hormone for induction of ovulation in hypogonadotropic amenorrhea. J Clin Endocrinol Metab. 1993;77(1):125–9.PubMed

27.

Tjon-Kon-Fat RI, Bensdorp AJ, Scholten I, Repping S, van Wely M, Mol BWJ, et al. IUI and IVF for unexplained subfertility: where did we go wrong? Hum Reprod. 2016;31(12):2665–7.CrossRefPubMed

28.

O'Flynn N. Assessment and treatment for people with fertility problems: NICE guideline. Br J Gen Pract. 2014;64(618):50–1.CrossRefPubMedPubMedCentral

29.

Kim D, Child T, Farquhar C. Intrauterine insemination: a UK survey on the adherence to NICE clinical guidelines by fertility clinics. BMJ Open. 2015;5(5):e007588.CrossRefPubMedPubMedCentral

30.

Nandi A, Gudi A, Shah A, Homburg R. An online survey of specialists’ opinion on first line management options for unexplained subfertility. Hum Fertil (Camb). 2015;18(1):48–53.CrossRef

31.

Farquhar CM, Liu E, Armstrong S, Arroll N, Lensen S, Brown J. Intrauterine insemination with ovarian stimulation versus expectant management for unexplained infertility (TUI): a pragmatic, open-label, randomised, controlled, two-centre trial. Lancet. 2018;391(10119):441–50.CrossRefPubMed

32.

“Bundesgesetz über die medizinisch unterstützte Fortpflanzung”. Swiss Constitution / Bundesverfassung, 1998(810.11).

33.

Van den Bergh M, et al. Ten years of Swiss national IVF register FIVNAT-CH. Are we making progress? Reprod BioMed Online. 2005;11(5):632–40.CrossRefPubMed

34.

“Bundesgesetz über die medizinisch unterstützte Fortpflanzung”, . Swiss Constitution / Bundesverfassung, 2017. 810.11.

35.

Maheshwari A, Griffiths S, Bhattacharya S. Global variations in the uptake of single embryo transfer. Hum Reprod Update. 2011;17(1):107–20.CrossRefPubMed

36.

Templeton A. Avoiding multiple pregnancies in ART: replace as many embryos as you like-one at a time. Hum Reprod. 2000;15(8):1662.CrossRefPubMed

37.

Gleicher N, Barad D. The relative myth of elective single embryo transfer. Hum Reprod. 2006;21(6):1337–44.CrossRefPubMed

38.

Bundesamt für Statistik / Swiss National Department of Statistics. https://www.bfs.admin.ch.

Title: Local privileges not universal rights: geographic variations in the science and clinical practice of reproductive medicine
Author: Alexander M. Quaas
Publication date: 01-09-2018
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 9/2018
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-018-1249-7

At a glance: The STEP trials

Springer Medicine

Local privileges not universal rights: geographic variations in the science and clinical practice of reproductive medicine

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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