Skip to main content
Top
Published in: BMC Medicine 1/2018

Open Access 01-12-2018 | Research article

Living at home after emergency hospital admission: prospective cohort study in older adults with and without cognitive spectrum disorder

Authors: Jennifer K. Burton, Bruce Guthrie, Simona M. Hapca, Vera Cvoro, Peter T. Donnan, Emma L. Reynish

Published in: BMC Medicine | Issue 1/2018

Login to get access

Abstract

Background

Cognitive spectrum disorders (CSDs) are common in hospitalised older adults and associated with adverse outcomes. Their association with the maintenance of independent living has not been established. The aim was to establish the role of CSDs on the likelihood of living at home 30 days after discharge or being newly admitted to a care home.

Methods

A prospective cohort study with routine data linkage was conducted based on admissions data from the acute medical unit of a district general hospital in Scotland. 5570 people aged ≥ 65 years admitted from a private residence who survived to discharge and received the Older Persons Routine Acute Assessment (OPRAA) during an incident emergency medical admission were included.
The outcome measures were living at home, defined as a private residential address, 30 days after discharge and new care home admission at hospital discharge. Outcomes were ascertained through linkage to routine data sources.

Results

Of the 5570 individuals admitted from a private residence who survived to discharge, those without a CSD were more likely to be living at home at 30 days than those with a CSD (93.4% versus 81.7%; difference 11.7%, 95%CI 9.7–13.8%). New discharge to a care home affected 236 (4.2%) of the cohort, 181 (76.7%) of whom had a CSD. Logistic regression modelling identified that all four CSD categories were associated with a reduced likelihood of living at home and an increased likelihood of discharge to a care home. Those with delirium superimposed on dementia were the least likely to be living at home (OR 0.25), followed by those with dementia (OR 0.43), then unspecified cognitive impairment (OR 0.55) and finally delirium (OR 0.57).

Conclusions

Individuals with a CSD are at significantly increased risk of not returning home after hospitalisation, and those with CSDs account for the majority of new admissions to care homes on discharge. Individuals with delirium superimposed on dementia are the most affected. We need to understand how to configure and deliver healthcare services to enable older people to remain as independent as possible for as long as possible and to ensure transitions of care are managed supportively.
Literature
3.
go back to reference Reynish EL, Hapca SM, De Souza N, Cvoro V, Donnan PT, Guthrie B. Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions. BMC Med. 2017;15(1):140.CrossRefPubMedPubMedCentral Reynish EL, Hapca SM, De Souza N, Cvoro V, Donnan PT, Guthrie B. Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions. BMC Med. 2017;15(1):140.CrossRefPubMedPubMedCentral
4.
go back to reference Jackson T, Gladman J, Harwood R, MacLullich A, Sampson E, Sheehan B, et al. Challenges and opportunities in understanding dementia and delirium in the acute hospital. PLoS Med. 2017;14(3):e1002247.CrossRefPubMedPubMedCentral Jackson T, Gladman J, Harwood R, MacLullich A, Sampson E, Sheehan B, et al. Challenges and opportunities in understanding dementia and delirium in the acute hospital. PLoS Med. 2017;14(3):e1002247.CrossRefPubMedPubMedCentral
5.
go back to reference Zisberg A, Sinoff G, Agmon M, Tonkikh O, Gur-Yaish N, Shadmi E. Even a small change can make a big difference: the case of in-hospital cognitive decline and new IADL dependency. Age Ageing. 2016;45(4):500–4.CrossRefPubMed Zisberg A, Sinoff G, Agmon M, Tonkikh O, Gur-Yaish N, Shadmi E. Even a small change can make a big difference: the case of in-hospital cognitive decline and new IADL dependency. Age Ageing. 2016;45(4):500–4.CrossRefPubMed
6.
go back to reference Fogg C, Meredith P, Bridges J, Gould GP, Griffiths P. The relationship between cognitive impairment, mortality and discharge characteristics in a large cohort of older adults with unscheduled admissions to an acute hospital: a retrospective observational study. Age Ageing. 2017;46(5):794–801.CrossRefPubMedPubMedCentral Fogg C, Meredith P, Bridges J, Gould GP, Griffiths P. The relationship between cognitive impairment, mortality and discharge characteristics in a large cohort of older adults with unscheduled admissions to an acute hospital: a retrospective observational study. Age Ageing. 2017;46(5):794–801.CrossRefPubMedPubMedCentral
9.
go back to reference Robinson SM, Ni Bhuachalla B, Ni Mhaille B, Cotter PE, O'Connor M, O'Keeffe ST. Home, please: a conjoint analysis of patient preferences after a bad hip fracture. Geriatr Gerontol Int. 2015;15(10):1165–70.CrossRefPubMed Robinson SM, Ni Bhuachalla B, Ni Mhaille B, Cotter PE, O'Connor M, O'Keeffe ST. Home, please: a conjoint analysis of patient preferences after a bad hip fracture. Geriatr Gerontol Int. 2015;15(10):1165–70.CrossRefPubMed
10.
go back to reference Woodman C, Baillie J, Sivell S. The preferences and perspectives of family caregivers towards place of care for their relatives at the end-of-life. A systematic review and thematic synthesis of the qualitative evidence. BMJ Support Palliat Care. 2015;6(4):418–29. Woodman C, Baillie J, Sivell S. The preferences and perspectives of family caregivers towards place of care for their relatives at the end-of-life. A systematic review and thematic synthesis of the qualitative evidence. BMJ Support Palliat Care. 2015;6(4):418–29.
14.
go back to reference Harrison JK, Walesby KE, Hamilton L, Armstrong C, Starr JM, Reynish EL, et al. Predicting discharge to institutional long-term care following acute hospitalisation: a systematic review & meta-analysis. Age Ageing. 2017;46(4):547–58.CrossRefPubMedPubMedCentral Harrison JK, Walesby KE, Hamilton L, Armstrong C, Starr JM, Reynish EL, et al. Predicting discharge to institutional long-term care following acute hospitalisation: a systematic review & meta-analysis. Age Ageing. 2017;46(4):547–58.CrossRefPubMedPubMedCentral
16.
go back to reference Ellis G, Gardner M, Tsiachristas A, Langhorne P, Burke O, Harwood RH, et al. Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev. 2017;9:Cd006211.PubMed Ellis G, Gardner M, Tsiachristas A, Langhorne P, Burke O, Harwood RH, et al. Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev. 2017;9:Cd006211.PubMed
18.
go back to reference Charlson M, Szatrowski T, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245–51.CrossRefPubMed Charlson M, Szatrowski T, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245–51.CrossRefPubMed
19.
go back to reference O’Sullivan D, Brady N, Manning E, O’Shea E, O’Grady S, O’Regan N, et al. Validation of the 6-item cognitive impairment test and the 4AT test for combined delirium and dementia screening in older emergency department attendees. Age Ageing. 2018;47(1):61–8.CrossRefPubMed O’Sullivan D, Brady N, Manning E, O’Shea E, O’Grady S, O’Regan N, et al. Validation of the 6-item cognitive impairment test and the 4AT test for combined delirium and dementia screening in older emergency department attendees. Age Ageing. 2018;47(1):61–8.CrossRefPubMed
20.
go back to reference Sampson E, Blanchard M, Jones L, Tookman A, King M. Dementia in the acute hospital: prospective cohort study of prevalence and mortality. Br J Psychiatry. 2009;195(1):61–6.CrossRefPubMed Sampson E, Blanchard M, Jones L, Tookman A, King M. Dementia in the acute hospital: prospective cohort study of prevalence and mortality. Br J Psychiatry. 2009;195(1):61–6.CrossRefPubMed
21.
go back to reference Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017;43(8):1105–22.CrossRefPubMedPubMedCentral Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017;43(8):1105–22.CrossRefPubMedPubMedCentral
22.
go back to reference Jackson TA, MacLullich AMJ, Gladman JRF, Lord JM, Sheehan B. Diagnostic test accuracy of informant-based tools to diagnose dementia in older hospital patients with delirium: a prospective cohort study. Age Ageing. 2016;45(4):505–11.CrossRefPubMed Jackson TA, MacLullich AMJ, Gladman JRF, Lord JM, Sheehan B. Diagnostic test accuracy of informant-based tools to diagnose dementia in older hospital patients with delirium: a prospective cohort study. Age Ageing. 2016;45(4):505–11.CrossRefPubMed
23.
go back to reference Romero-Ortuno R, Forsyth DR, Wilson KJ, Cameron E, Wallis S, Biram R, et al. The Association of Geriatric Syndromes with hospital outcomes. J Hosp Med. 2017;12(2):83–9.CrossRefPubMed Romero-Ortuno R, Forsyth DR, Wilson KJ, Cameron E, Wallis S, Biram R, et al. The Association of Geriatric Syndromes with hospital outcomes. J Hosp Med. 2017;12(2):83–9.CrossRefPubMed
24.
go back to reference Clegg A, Bates C, Young J, Ryan R, Nichols L, Teale EA, et al. Development and validation of an electronic frailty index using routine primary care electronic health record data. Age Ageing. 2016;45(3):353–60.CrossRefPubMedPubMedCentral Clegg A, Bates C, Young J, Ryan R, Nichols L, Teale EA, et al. Development and validation of an electronic frailty index using routine primary care electronic health record data. Age Ageing. 2016;45(3):353–60.CrossRefPubMedPubMedCentral
25.
go back to reference Campbell SE, Seymour DG, Primrose WR, Lynch JE, Dunstan E, Espallargues M, et al. A multi-Centre European study of factors affecting the discharge destination of older people admitted to hospital: analysis of in-hospital data from the ACMEplus project. Age Ageing. 2005;34(5):467–75.CrossRefPubMed Campbell SE, Seymour DG, Primrose WR, Lynch JE, Dunstan E, Espallargues M, et al. A multi-Centre European study of factors affecting the discharge destination of older people admitted to hospital: analysis of in-hospital data from the ACMEplus project. Age Ageing. 2005;34(5):467–75.CrossRefPubMed
26.
go back to reference Witlox J, Eurelings LS, de Jonghe JF, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA. 2010;304(4):443–51.CrossRefPubMed Witlox J, Eurelings LS, de Jonghe JF, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA. 2010;304(4):443–51.CrossRefPubMed
27.
go back to reference Sheehan B, Lall R, Gage H, Holland C, Katz J, Mitchell K. A 12-month follow-up study of people with dementia referred to general hospital liaison psychiatry services. Age Ageing. 2013;42(6):786–90.CrossRefPubMed Sheehan B, Lall R, Gage H, Holland C, Katz J, Mitchell K. A 12-month follow-up study of people with dementia referred to general hospital liaison psychiatry services. Age Ageing. 2013;42(6):786–90.CrossRefPubMed
28.
go back to reference Morandi A, Davis D, Fick DM, Turco R, Boustani M, Lucchi E, et al. Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients. J Am Med Dir Assoc. 2014;15(5):349–54.CrossRefPubMedPubMedCentral Morandi A, Davis D, Fick DM, Turco R, Boustani M, Lucchi E, et al. Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients. J Am Med Dir Assoc. 2014;15(5):349–54.CrossRefPubMedPubMedCentral
29.
go back to reference Kelly S, Lafortune L, Hart N, Cowan K, Fenton M, Brayne C. Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda. Age Ageing. 2015;44(6):985–93.CrossRefPubMedPubMedCentral Kelly S, Lafortune L, Hart N, Cowan K, Fenton M, Brayne C. Dementia priority setting partnership with the James Lind Alliance: using patient and public involvement and the evidence base to inform the research agenda. Age Ageing. 2015;44(6):985–93.CrossRefPubMedPubMedCentral
30.
go back to reference Cole L, Samsi K, Manthorpe J. Is there an “optimal time” to move to a care home for a person with dementia? A systematic review of the literature. Int Psychogeriatr. 2018:1–22. Cole L, Samsi K, Manthorpe J. Is there an “optimal time” to move to a care home for a person with dementia? A systematic review of the literature. Int Psychogeriatr. 2018:1–22.
31.
go back to reference Afram B, Stephan A, Verbeek H, Bleijlevens MHC, Suhonen R, Sutcliffe C, et al. Reasons for institutionalization of people with dementia: informal caregiver reports from 8 European countries. J Am Med Dir Assoc. 2014;15(2):108–16.CrossRefPubMed Afram B, Stephan A, Verbeek H, Bleijlevens MHC, Suhonen R, Sutcliffe C, et al. Reasons for institutionalization of people with dementia: informal caregiver reports from 8 European countries. J Am Med Dir Assoc. 2014;15(2):108–16.CrossRefPubMed
32.
go back to reference Fick DM, Agostini JV, Inouye SK. Delirium superimposed on dementia: a systematic review. J Am Geriatr Soc. 2002;50(10):1723–32.CrossRefPubMed Fick DM, Agostini JV, Inouye SK. Delirium superimposed on dementia: a systematic review. J Am Geriatr Soc. 2002;50(10):1723–32.CrossRefPubMed
33.
go back to reference Livingston G, Sommerlad A, Orgeta V, Costafreda SG, Huntley J, Ames D, et al. Dementia prevention, intervention, and care. Lancet (London, England). 2017;390(10113):2673–734. Livingston G, Sommerlad A, Orgeta V, Costafreda SG, Huntley J, Ames D, et al. Dementia prevention, intervention, and care. Lancet (London, England). 2017;390(10113):2673–734.
34.
go back to reference Kingston A, Robinson L, Booth H, Knapp M, Jagger C. Projections of multi-morbidity in the older population in England to 2035: estimates from the population ageing and care simulation (PACSim) model. Age Ageing. 2018;47(3):374–80. Kingston A, Robinson L, Booth H, Knapp M, Jagger C. Projections of multi-morbidity in the older population in England to 2035: estimates from the population ageing and care simulation (PACSim) model. Age Ageing. 2018;47(3):374–80.
35.
go back to reference Handley M, Bunn F, Goodman C. Dementia-friendly interventions to improve the care of people living with dementia admitted to hospitals: a realist review. BMJ Open. 2017;7(7):e015257. Handley M, Bunn F, Goodman C. Dementia-friendly interventions to improve the care of people living with dementia admitted to hospitals: a realist review. BMJ Open. 2017;7(7):e015257.
36.
go back to reference George J, Long S, Vincent C. How can we keep patients with dementia safe in our acute hospitals? A review of challenges and solutions. J R Soc Med. 2013;106(9):355–61.CrossRefPubMedPubMedCentral George J, Long S, Vincent C. How can we keep patients with dementia safe in our acute hospitals? A review of challenges and solutions. J R Soc Med. 2013;106(9):355–61.CrossRefPubMedPubMedCentral
37.
go back to reference Watkin L, Blanchard MR, Tookman A, Sampson EL. Prospective cohort study of adverse events in older people admitted to the acute general hospital: risk factors and the impact of dementia. International Journal of Geriatric Psychiatry. 2012;27(1):76–82.CrossRefPubMed Watkin L, Blanchard MR, Tookman A, Sampson EL. Prospective cohort study of adverse events in older people admitted to the acute general hospital: risk factors and the impact of dementia. International Journal of Geriatric Psychiatry. 2012;27(1):76–82.CrossRefPubMed
38.
go back to reference Dharmarajan K, Swami S, Gou RY, Jones RN, Inouye SK. Pathway from delirium to death: potential in-hospital mediators of excess mortality. J Am Geriatr Soc. 2017;65(5):1026–33.CrossRefPubMed Dharmarajan K, Swami S, Gou RY, Jones RN, Inouye SK. Pathway from delirium to death: potential in-hospital mediators of excess mortality. J Am Geriatr Soc. 2017;65(5):1026–33.CrossRefPubMed
39.
go back to reference Inouye S, van Dyck C, Alessi C, Balkin S, Siegal A, Horwitz R. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med. 1990;113:941–8.CrossRefPubMed Inouye S, van Dyck C, Alessi C, Balkin S, Siegal A, Horwitz R. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med. 1990;113:941–8.CrossRefPubMed
40.
go back to reference Hodkinson HM. Evaluation of a mental test score for assessment of mental impairment in the elderly. Age Ageing. 1972;1(4):233–8.CrossRefPubMed Hodkinson HM. Evaluation of a mental test score for assessment of mental impairment in the elderly. Age Ageing. 1972;1(4):233–8.CrossRefPubMed
41.
go back to reference Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963;185:914–9.CrossRefPubMed Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963;185:914–9.CrossRefPubMed
Metadata
Title
Living at home after emergency hospital admission: prospective cohort study in older adults with and without cognitive spectrum disorder
Authors
Jennifer K. Burton
Bruce Guthrie
Simona M. Hapca
Vera Cvoro
Peter T. Donnan
Emma L. Reynish
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2018
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/s12916-018-1199-z

Other articles of this Issue 1/2018

BMC Medicine 1/2018 Go to the issue