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Pediatric Surgery International
Published in: Pediatric Surgery International 9/2022

23-07-2022 | Liver Transplantation | Review Article

The survival rate of liver transplantation in children: a systematic review and meta-analysis

Authors: Mousa Ghelichi-Ghojogh, Mostafa Javanian, Sanaz Amiri, Mohebat Vali, Saman Sedighi, Abdolhalim Rajabi, Layla Shojaie, Leila Moftakhar, Rokhan Khezri, Masoud Mohammadi, Hossein-Ali Nikbakht

Published in: Pediatric Surgery International | Issue 9/2022

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Abstract

Liver transplantation is a life-saving treatment for children who are in liver failure. The survival rate index is used to assess the success rate of liver transplantation. The study aimed to assess the survival rate of liver transplantation in children. We searched 5 international databases in this study, including Medline/PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar, for published articles by the end of 2020. Also, meta-regression analysis was performed based on the year of the study, and subgroup analysis was performed according to continents. A total of 425 titles were reviewed. Based on the results, 96 articles were entered in the meta-analysis. Established on the random-effect model, the survival rates of 1, 3, 5, and 10 years of transplantation were 86.62%, 77.74%, 73.95%, and 68.60%, respectively. Also, based on the meta-regression results, there was a relationship between the year of the study and the survival rate, as the study year gets more recent, the survival rate is increased. This study can provide documented and comprehensive evidence which can be the basis of many policies and decisions in various sectors of health development, including evaluating treatment options and health interventions in transplantation.
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Metadata
Title
The survival rate of liver transplantation in children: a systematic review and meta-analysis
Authors
Mousa Ghelichi-Ghojogh
Mostafa Javanian
Sanaz Amiri
Mohebat Vali
Saman Sedighi
Abdolhalim Rajabi
Layla Shojaie
Leila Moftakhar
Rokhan Khezri
Masoud Mohammadi
Hossein-Ali Nikbakht
Publication date
23-07-2022
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 9/2022
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-022-05179-y

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