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01-12-2024 | Liver Transplantation | Original Article

Risk factors for post-operative portal vein stenosis in pediatric liver transplantation: a single center case-control study

Authors: Yigang Qian, Wei Zhang, Weili Wang, Zhiwei Li, Yi Shao, Shunliang Gao, Jian Wu, Jun Yu, Min Zhang, Yan Shen, Xueli Bai, Tingbo Liang

Published in: Pediatric Surgery International | Issue 1/2024

Abstract

Purpose

The incidence of post-transplant poral vein stenosis (PVS) is higher in pediatric liver transplantation, probably resulting from various portal vein (PV) reconstruction methods or other factors.

Methods

332 patients less than 12 years old when receiving liver transplantation (LT) were enrolled in this research. Portal vein reconstruction methods include anastomosis to the left side of the recipient PV trunk (type 1, n = 170), to the recipient left and right PV branch patch (type 2, n = 79), using vein graft interposition (type 3, n = 32), or end-to-end PV anastomosis (type 4, n = 50). The incidence of PVS was analyzed in terms to different PV reconstruction methods and other possible risk factors.

Results

PVS occurred in 35 (10.5%) patients. Of the 32 patients using vein graft, 20 patients received a cryopreserved vein graft, 11 (55%) developed PVS, while the remaining 12 patients received a fresh iliac vein for PV interposition and none of them developed PVS. 9 patients whose liver donor was under 12 years old developed PVS, with an incidence of 18.8%.

Conclusion

Cryopreserved vein graft interposition and a liver donor under 12 are independent risk factors for PVS in pediatric LT.

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Title: Risk factors for post-operative portal vein stenosis in pediatric liver transplantation: a single center case-control study
Authors: Yigang Qian
Wei Zhang
Weili Wang
Zhiwei Li
Yi Shao
Shunliang Gao
Jian Wu
Jun Yu
Min Zhang
Yan Shen
Xueli Bai
Tingbo Liang
Publication date: 01-12-2024
Publisher: Springer Berlin Heidelberg
Keywords: Liver Transplantation
Liver Transplantation
Liver Transplantation
Liver Transplantation
Liver Transplantation
Published in: Pediatric Surgery International / Issue 1/2024
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-024-05690-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Risk factors for post-operative portal vein stenosis in pediatric liver transplantation: a single center case-control study

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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