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Journal of Gastrointestinal Surgery

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01-10-2011 | Original Article

Liver Resection Without Pedicle Clamping: Feasibility and Need for “Salvage Clamping”. Looking for the Right Clamping Policy. Analysis of 512 Consecutive Resections

Authors: Luca Viganò, Syed A. A. Jaffary, Alessandro Ferrero, Nadia Russolillo, Serena Langella, Lorenzo Capussotti

Published in: Journal of Gastrointestinal Surgery | Issue 10/2011

Abstract

Background

Pedicle clamping during liver resection (LR) is debated. The purpose of this study is to validate non-clamping policy across a large series of LR and to evaluate the need for salvage clamping (SC) and its outcomes.

Methods

Five hundred twelve consecutive LR without initial pedicle clamping performed between 2004 and 2009 were analyzed.

Results

Among 512 LR (171 major hepatectomies), 90.2% were completed without clampage. Fifty (9.8%) required SC. Blood loss were higher in SC group (555 vs. 175 mL, p < 0.0001), while transfusion rate was not. No differences were observed in terms of mortality (0%/1.3%), morbidity (38%/38.3%), liver dysfunction (4%/3.7%), and renal dysfunction (0%/1.3%). Bile leak rate was increased in the SC group (20%/10.2%, p = 0.036). At multivariate analysis, three predictive factors of SC were identified: arterial hypertension (p = 0.007, SC rate = 13%), cirrhosis (p = 0.003, SC rate = 26%), and LR conducted along the right portal scissure (p = 0.010, SC rate = 32%). One protective factor was identified: LR confined to antero-lateral segments (Sg2–6, p = 0.001, SC rate = 2%). Extension of LR had no impact on need for SC.

Conclusions

The majority of LR can be safely performed without clamping with excellent outcomes. SC is a safe procedure and does not worsen postoperative outcomes, except for bile leak rate. Clamping policy should be tailored to the type of LR and presence of cirrhosis.

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Title: Liver Resection Without Pedicle Clamping: Feasibility and Need for “Salvage Clamping”. Looking for the Right Clamping Policy. Analysis of 512 Consecutive Resections
Authors: Luca Viganò
Syed A. A. Jaffary
Alessandro Ferrero
Nadia Russolillo
Serena Langella
Lorenzo Capussotti
Publication date: 01-10-2011
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 10/2011
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-011-1625-4

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Liver Resection Without Pedicle Clamping: Feasibility and Need for “Salvage Clamping”. Looking for the Right Clamping Policy. Analysis of 512 Consecutive Resections

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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