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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 8/2014

01-08-2014 | Case Report

Liver Metastasis as the Initial Presentation of Adenoid Cystic Carcinoma

Authors: Gaya Spolverato, Judd Fite, Justin Bishop, Pedram Argani, Timothy M. Pawlik

Published in: Digestive Diseases and Sciences | Issue 8/2014

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Excerpt

Adenoid cystic carcinoma (ACC) is a rare cancer of the salivary gland arising from myoepithelial cells, accounting for 10 % of salivary carcinoma and <1 % of head and neck tumors [1]. The natural history of ACC can be varied. A subset of patients with ACC can have an aggressive clinical course often characterized by a high incidence of local recurrence. Up to 40 % of submandibular gland ACC tumors can metastasize distally, with the lung, bone, brain, and liver being the most common sites [2, 3]. Very few cases have been reported with liver metastasis as the initial presentation of ACC [4, 5]. …
Literature
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Matsuba HM, Spector GJ, Thawley SE, Simpson JR, Mauney M, Pikul FJ. Adenoid cystic salivary gland carcinoma. A histopathologic review of treatment failure patterns. Cancer. 1986;57:519–524.PubMedCrossRef
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Balducci G, Sagnotta A, Muroni M, Cacchi C, D’Amato A. An unusual case of exclusive liver metastases from adenoid cystic carcinoma of the submandibular gland: a role for surgery? Report of a case. Surgery Today. 2011;41:596–599.PubMedCrossRef
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Spiro RH, Huvos AG, Strong EW. Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242 cases. Am J Surg. 1974;128:512–520.PubMedCrossRef
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Garg N, Tomar R, Goyal S, Singh UR. Isolated liver metastases in an adenoid cystic carcinoma of the submandibular gland on fine needle aspiration cytology: an unusual presentation. Cytopathology. 2014;25:133–140.
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Metadata
Title
Liver Metastasis as the Initial Presentation of Adenoid Cystic Carcinoma
Authors
Gaya Spolverato
Judd Fite
Justin Bishop
Pedram Argani
Timothy M. Pawlik
Publication date
01-08-2014
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 8/2014
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-014-3078-6

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