Skip to main content
Top
Published in: Oral Radiology 4/2021

01-10-2021 | Lipoma | Review Article

Osteolipoma: a review of the literature and a rare case report

Authors: Hulya Cakir Karabas, Ilknur Ozcan, Merva Soluk Tekkesin, Sabri Cemil Isler

Published in: Oral Radiology | Issue 4/2021

Login to get access

Abstract

Objectives

Lipomas are the most common benign mesenchymal tumors of soft tissue. According to previous studies, 1–4% of the cases has been observed in the oral cavity. A histological variant of lipoma featuring bone formation is called osteolipoma and has been very rarely observed (less than 1% of the total). In order to make a meaningful addition to this rare knowledge base, our study aims to provide a literature review and to report an additional case of osteolipoma.

Methods

An electronic search in the PubMed database with the keyword “osteolipoma” was conducted. Among 69 search results, only the cases of osteolipoma located in the “oral cavity” were included in this study. The findings of the previously reported 20 cases (in English) of osteolipoma of the oral cavity were organized in a table along with a new case of osteolipoma located in the mandibular buccal vestibule with radiological and histopathological findings provided by the authors.

Results

Osteolipoma affects both sexes and usually emerges in middle-aged or elderly patients with a long history of slow progression. Different imaging techniques may be utilized in the radiographic evaluation.

Conclusion

Differential diagnosis includes a wide range of lesions; therefore, the clinical and radiographic evaluation should be confirmed by histopathological examination. The suggested treatment is complete surgical excision and follow-up, and the prognosis is generally good.
Literature
2.
go back to reference Firth NA, Allsobrook OFL, Patel M. Osteolipoma of the buccal mucosa: a case report. Aust Dent J. 2017;62:378–81.CrossRef Firth NA, Allsobrook OFL, Patel M. Osteolipoma of the buccal mucosa: a case report. Aust Dent J. 2017;62:378–81.CrossRef
3.
go back to reference Saghafi S, Mellati E, Sohrabi M, Raahpeyma A, Salehinejad J, Zare-Mahmoodabadi R. Osteolipoma of the oral and pharyngeal region: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Oral Endod. 2008;105:e30-4.CrossRef Saghafi S, Mellati E, Sohrabi M, Raahpeyma A, Salehinejad J, Zare-Mahmoodabadi R. Osteolipoma of the oral and pharyngeal region: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Oral Endod. 2008;105:e30-4.CrossRef
4.
go back to reference Adebiyi KE, Ugboko VI, Maaji SM, Ndubuizu GTU. Osteolipoma of the palate: Report of a case and review of the literature. Niger J Clin Pract. 2011;14:242–4.CrossRef Adebiyi KE, Ugboko VI, Maaji SM, Ndubuizu GTU. Osteolipoma of the palate: Report of a case and review of the literature. Niger J Clin Pract. 2011;14:242–4.CrossRef
6.
go back to reference Raviraj J, Kumar-Bokkasam V, Suresh D, Venkata S. Osteolipoma of buccal mucosa: case report and literature review. J Clin Exp Dent. 2016;8:e214-8.PubMedPubMedCentral Raviraj J, Kumar-Bokkasam V, Suresh D, Venkata S. Osteolipoma of buccal mucosa: case report and literature review. J Clin Exp Dent. 2016;8:e214-8.PubMedPubMedCentral
7.
go back to reference Amaral MBF, Borges CF, de Freitas JB, Capistrano HM, Mesquita RA. Osteolipoma of the oral cavity: a case report. J Maxillofac Oral Surg. 2015;14:195–9.CrossRef Amaral MBF, Borges CF, de Freitas JB, Capistrano HM, Mesquita RA. Osteolipoma of the oral cavity: a case report. J Maxillofac Oral Surg. 2015;14:195–9.CrossRef
8.
go back to reference de Castro A, de Castro E-V-F-L, Felipini R-C, Ribeiro A-C-P, Soubnia A-M-P. Osteolipoma of the buccal mucosa. Med Oral Patol Oral Cir Bucal. 2010;15:347–9.CrossRef de Castro A, de Castro E-V-F-L, Felipini R-C, Ribeiro A-C-P, Soubnia A-M-P. Osteolipoma of the buccal mucosa. Med Oral Patol Oral Cir Bucal. 2010;15:347–9.CrossRef
9.
go back to reference Fritchie KJ, Renner JB, Rao KW, Esther RJ. Osteolipoma: Radiological, pathological, and cytogenetic analysis of three cases. Skelet Radiol. 2012;41:237–44.CrossRef Fritchie KJ, Renner JB, Rao KW, Esther RJ. Osteolipoma: Radiological, pathological, and cytogenetic analysis of three cases. Skelet Radiol. 2012;41:237–44.CrossRef
10.
go back to reference Gaskin CM, Helms CA. Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. Am J Roentgenol. 2004;182:733–9.CrossRef Gaskin CM, Helms CA. Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. Am J Roentgenol. 2004;182:733–9.CrossRef
11.
go back to reference Piattelli A, Fioroni M, Iezzi G, Rubini C. Osteolipoma of the tongue. Oral Oncol. 2001;37:468–70.CrossRef Piattelli A, Fioroni M, Iezzi G, Rubini C. Osteolipoma of the tongue. Oral Oncol. 2001;37:468–70.CrossRef
12.
go back to reference Raghunath V, Manjunatha BS. Osteolipoma of floor of the mouth. BMJ Case Rep. 2015;1–3. Raghunath V, Manjunatha BS. Osteolipoma of floor of the mouth. BMJ Case Rep. 2015;1–3.
13.
go back to reference H Yoshimura S Ohba Y Imamura 2018 Sano K Osseous choristoma of the tongue. A case report with dermoscopic study Mol Clin Oncol 8 242 5 H Yoshimura S Ohba Y Imamura 2018 Sano K Osseous choristoma of the tongue. A case report with dermoscopic study Mol Clin Oncol 8 242 5
14.
go back to reference Soulard R, Nguyen AT, Souraud JB, Oddon PA, Fouet B, Cathelinaud O. Osteochondrolipoma of the submandibular region: a case report and review of the literature. Head Neck Pathol. 2012;6:486–91.CrossRef Soulard R, Nguyen AT, Souraud JB, Oddon PA, Fouet B, Cathelinaud O. Osteochondrolipoma of the submandibular region: a case report and review of the literature. Head Neck Pathol. 2012;6:486–91.CrossRef
15.
go back to reference Seelam S, Beeram RK. Osteolipoma in the retromolartrigone: a case report and review of literature. Ann Maxillofac Surg. 2016;6:304–7.CrossRef Seelam S, Beeram RK. Osteolipoma in the retromolartrigone: a case report and review of literature. Ann Maxillofac Surg. 2016;6:304–7.CrossRef
16.
go back to reference Godby A, Drez P, Field J. Sublingual lipoma with ectopic bone formation: report of a case. Oral Surg Oral Med Oral Pathol. 1961;14:625–9.CrossRef Godby A, Drez P, Field J. Sublingual lipoma with ectopic bone formation: report of a case. Oral Surg Oral Med Oral Pathol. 1961;14:625–9.CrossRef
17.
go back to reference Hughes CL. Intraoral lipoma with osseous metaplasia. Report of a case. Oral Surgery, Oral Med Oral Pathol. 1966;21:576–8.CrossRef Hughes CL. Intraoral lipoma with osseous metaplasia. Report of a case. Oral Surgery, Oral Med Oral Pathol. 1966;21:576–8.CrossRef
18.
go back to reference Allard RHB, Blok P, van der Kwast WAM, van der Waal I. Oral lipomas with osseous and chondrous metaplasia; report of two cases. J Oral Pathol Med. 1982;11:18–25.CrossRef Allard RHB, Blok P, van der Kwast WAM, van der Waal I. Oral lipomas with osseous and chondrous metaplasia; report of two cases. J Oral Pathol Med. 1982;11:18–25.CrossRef
19.
go back to reference Castilho RM, Squarize CH, Nunes FD, Pinto DS. Osteolipoma: a rare lesion in the oral cavity. Br J Oral Maxillofac Surg. 2004;42:363–4.CrossRef Castilho RM, Squarize CH, Nunes FD, Pinto DS. Osteolipoma: a rare lesion in the oral cavity. Br J Oral Maxillofac Surg. 2004;42:363–4.CrossRef
20.
go back to reference Gokul S, Ranjini KV, Kirankumar K, Hallikeri K. Congenital osteolipoma associated with cleft palate: a case report. Int J Oral Maxillofac Surg. 2009;38:91–3.CrossRef Gokul S, Ranjini KV, Kirankumar K, Hallikeri K. Congenital osteolipoma associated with cleft palate: a case report. Int J Oral Maxillofac Surg. 2009;38:91–3.CrossRef
21.
go back to reference Kuyama K, Fifita SF, Komiya M, Sun Y, Akimoto Y, Yamamoto H. Rare lipomatous tumors with osseous and/or chondroid differentiation in the oral cavity report of two cases and review of the literature. Int J Dent. 2009;2009:1–6.CrossRef Kuyama K, Fifita SF, Komiya M, Sun Y, Akimoto Y, Yamamoto H. Rare lipomatous tumors with osseous and/or chondroid differentiation in the oral cavity report of two cases and review of the literature. Int J Dent. 2009;2009:1–6.CrossRef
22.
go back to reference Juliasse LER, Nonaka CFW, Pinto LP, Freitas RDA, Miguel MCDC. Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population. Eur Arch Oto-Rhino-Laryngology. 2010;267:459–65.CrossRef Juliasse LER, Nonaka CFW, Pinto LP, Freitas RDA, Miguel MCDC. Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population. Eur Arch Oto-Rhino-Laryngology. 2010;267:459–65.CrossRef
23.
go back to reference Hsu H, Lee L, Chang K. Pathology Quiz Case 2. Arch Otolaryngol Head Neck Surg. 2012;138(1):97.CrossRef Hsu H, Lee L, Chang K. Pathology Quiz Case 2. Arch Otolaryngol Head Neck Surg. 2012;138(1):97.CrossRef
24.
go back to reference Silva PA, de Fernandes MT, F, Freire FS, . Raro caso de osteolipoma na cavidade oral. Rev Assoc Paul Cir Dent. 2013;67:198–201. Silva PA, de Fernandes MT, F, Freire FS, . Raro caso de osteolipoma na cavidade oral. Rev Assoc Paul Cir Dent. 2013;67:198–201.
25.
go back to reference Bajpai M, Kumar M, Agarwal D, Agrawal S, Gupta S, Kumar M. Osteolipoma of the palate: an unusual presentation. Natl J Maxillofac Surg. 2014;5:250–1.CrossRef Bajpai M, Kumar M, Agarwal D, Agrawal S, Gupta S, Kumar M. Osteolipoma of the palate: an unusual presentation. Natl J Maxillofac Surg. 2014;5:250–1.CrossRef
Metadata
Title
Osteolipoma: a review of the literature and a rare case report
Authors
Hulya Cakir Karabas
Ilknur Ozcan
Merva Soluk Tekkesin
Sabri Cemil Isler
Publication date
01-10-2021
Publisher
Springer Singapore
Keywords
Lipoma
Lipoma
Published in
Oral Radiology / Issue 4/2021
Print ISSN: 0911-6028
Electronic ISSN: 1613-9674
DOI
https://doi.org/10.1007/s11282-020-00500-8

Other articles of this Issue 4/2021

Oral Radiology 4/2021 Go to the issue