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Archives of Gynecology and Obstetrics

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01-09-2008 | Case Report

Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor

Authors: Metin Akbulut, Osman Zekioglu, Mustafa Cosan Terek, Necmettin Ozdemir

Published in: Archives of Gynecology and Obstetrics | Issue 3/2008

Abstract

Objective

Adenofibroma is a form of mixed mesodermal tumor in which epithelial and stromal components are benign, and usually arises in the endometrium of postmenopausal women. We report a case of lipoadenofibroma of the endometrium that appeared as an intracavitary mass, which is very unusual because endometrioid adenofibroma rarely contains mature adipose tissue, only the second such case described in detail.

Case

An endometrial polypoid mass measuring 1,5 cm with maximum diameter was found incidentally during total abdominal hysterectomy for keratinizing large cell carcinoma of the cervix in a 60-year-old woman. The endometrial polypoid mass was found to be a lipoadenofibroma composed predominantly of collagenated fibrous stroma populated by cystically dilated and occasionally crowded glands lined with proliferative endometrium, intermingled with abundant mature adipose tissue.

Conclusion

We suggest that uterine adenofibromas with lipomatous areas belong to the family of mixed tumor of Mullerian origin. We discuss the pathogenesis of this entity and review the previously documented similar cases.

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Title: Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor
Authors: Metin Akbulut
Osman Zekioglu
Mustafa Cosan Terek
Necmettin Ozdemir
Publication date: 01-09-2008
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 3/2008
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-008-0572-0

At a glance: The STEP trials

Springer Medicine

Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor

Abstract

Objective

Case

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Case

Conclusion

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