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American Journal of Clinical Dermatology

Published in:

01-04-2006 | Review Article

Assessing Quality of Life in Patients with Acne Vulgaris

Implications for Treatment

Author: Prof. Brigitte Dréno

Published in: American Journal of Clinical Dermatology | Issue 2/2006

Abstract

Diagnosing acne is easy. However, treatment must be adapted to the type and severity of acne, and must also take into account the impact of acne on patients’ quality of life. As there is not always a correlation between the severity of acne and its impact on quality of life, it can be helpful for the dermatologist to use a quality of life scale to determine the psychological impact of acne on patients. Either global scales or specific scales for acne can be used. This article reviews the different scales used for evaluation of quality of life in patients with acne.

Consideration of specific scales suggests that the Acne Disability Index/Cardiff Acne Disability Index is the easiest scale to use in routine dermatology practice. The Acne Quality of Life scale is particularly useful for evaluating anxiety and depression. The Acne-Specific Quality of Life questionnaire has been mainly validated in adult acne. The Assessment of the Psychological and Social Effects of Acne scale has yet to be validated. Clinical trials indicate that use of global and specific scales together has complementary benefits.

In the management of acne, evaluation of quality of life may help to detect depression in teenagers. It may also help to enhance adherence to treatment, which is a crucial factor for success. Finally, there are now validated quality of life scales that are easy to use during patient consultations (taking <2 minutes to complete) by clinicians wishing to evaluate quality of life in patients with acne.

The use of trade names is for product identification purposes only and does not imply endorsement.

Smithard A, Glazebrook C, Williams HC. Acne prevalence, knowledge about acne and psychological morbidity in mid-adolescence: a community-based study. Br J Dermatol 2001; 145: 274-9PubMedCrossRef

Fried RG, Shalita AR. Acné et psychisme: interactions. Cutis et Psyché 1992; 2: 28-34

Toyoda M, Nakamura M, Morohashi M. Neuropeptides and sebaceous glands. Fur J Dermatol 2002; 12: 422-7

Toyoda M, Nakamura M, Makino T, et al. Sebaceous glands in acne patients express high levels of neutral endopeptidases. Exp Dermatol 2002; 11: 241-7PubMedCrossRef

Green J, Sinclair RD. Perceptions of acne vulgaris in final year medical student written examination answers. Australas J Dermatol 2001; 42 (2): 98-101PubMedCrossRef

The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med 1995; 41: 1403-9

Cribier B. Acne and quality of life [in French]. Ann Dermatol Venereol 2000; 127 Suppl. 2: 2S13-4

Chren MM, Lasek RJ, Quinn LM, et al. Skindex, a quality of life measure for patients with skin disease: reliability, validity, and responsiveness. J Invest Dermatol 1996; 107: 707-13PubMedCrossRef

Lasek RJ, Chren MM. Acne vulgaris and the quality of life of adult dermatology patients. Arch Dermatol 1998; 134: 454-8PubMedCrossRef

10.

Hayashi N, Higaki Y, Kawamoto K, et al. A cross-sectional analysis of quality of life in Japanese acne patients using the Japanese version of Skindex-16. J Dermatol 2004; 31: 971-6PubMed

11.

Anderson RT, Rajagopalan R. Development and validation of a quality of life instrument for cutaneous diseases. J Am Acad Dermatol 1997; 37: 41-50PubMedCrossRef

12.

Anderson R, Rajagopalan R. Responsiveness of the Dermatology-Specific Quality of Life (DSQL) instrument to treatment for acne vulgaris in a placebo-controlled clinical trial. Qual Life Res 1998; 7: 723-34PubMedCrossRef

13.

Mosam A, Vawda NB, Gordhan AIL et al. Quality of life issues for South Africans with acne vulgaris. Clin Exp Dermatol 2005; 30: 6-9PubMedCrossRef

14.

Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19: 210-6PubMedCrossRef

15.

Mallon E, Newton IN, Klassen A, et al. The quality of life in acne: a comparison with general medical conditions using generic questionnaires. Br J Dermatol 1999; 140: 672-6PubMedCrossRef

16.

Klassen AF, Newton IN, Mallon E. Measuring quality of life in people referred for specialist care of acne: comparing generic and disease-specific measures. J Am Acad Dermatol 2000; 43: 229-33PubMedCrossRef

17.

Boehncke WH, Ochsendorf F, Paeslack I, et al. Decorative cosmetics improve the quality of life in patients with disfiguring skin diseases. Fur J Dermatol 2002; 12: 577-80

18.

Oakley AM. The Acne Disability Index: usefulness confirmed. Australas J Dermalot 1996; 37: 37-9CrossRef

19.

Salek MS, Khan GK, Finlay AY. Questionnaire techniques in assessing acne handicap: reliability and validity study. Qual Life Res 1996; 5: 131-8PubMedCrossRef

20.

Dréno B, Finlay AY, Nocera T, et al. The Cardiff Acne Disability Index: cultural and linguistic validation in French. Dermatology 2004; 208: 104-8PubMedCrossRef

21.

Girman CJ, Hartmeier S, Thiboudot D, et al. Evaluating health-related quality of life in patients with facial acne: development of a self-administered questionnaire for clinical trials. Qual Life Res 1996; 5: 481-90PubMedCrossRef

22.

Martin AR, Lookingbill DP, Botek A. Health related quality of life among patients with facial acne: assessment of a new acne-specific questionnaire. Clin Exp Dermatol 2001; 26: 381-5

23.

Fehnel SE, McLeod LD, Brandman J, et al. Responsiveness of the Acne-Specific Quality of Life questionnaire (Acne-QoL) to treatment for acne vulgaris in placebo-controlled clinical trials. Qual Life Res 2002; 11: 809-16PubMedCrossRef

24.

McLeod LD, Fehnel SE, Brandman J, et al. Evaluating minimal clinically important differences for the Acne-Specific Quality of Life questionnaire. Pharmacoeconomics 2003; 21: 1069-79PubMedCrossRef

25.

Gupta MA, Johnson MA, Gupta AK. The development of an Acne Quality of Life scale: reliability, validity, and relation to subjective acne severity in mild to moderate acne vulgaris. Acta Derm Venereol 1998; 78: 451-6PubMedCrossRef

26.

Yazici K, Baz K, Yazici AE, et al. Disease-specific quality of life is associated with anxiety and depression in patients with acne. J Fur Acad Dermatol Venereol 2004; 18: 435-9CrossRef

27.

Weiss JW, Shavin J, Davis M. Preliminary results of a nonrandomized, multicenter, open-label study of patient satisfaction after treatment with combination benzoyl peroxide/clindamycin topical gel for mild to moderate acne. Clin Ther 2002; 24: 1706-17PubMedCrossRef

28.

Layton AM, Eady A, Cunliffe WJ. A reassessment of acne: what constitutes severe acne? Br J Dermatol 1991; 125 Suppl. 38: 35-6

29.

Niemeier V, Kupfer J, Demmelbauer-Ebner M, et al. Coping with acne vulgaris: evaluation of the chronic skin disorder questionnaire in patients with acne. Dermatology 1998; 134: 454-8CrossRef

30.

Lewis-Jones MS, Finlay AY. The Children’s Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol 1995; 132: 942-9PubMedCrossRef

31.

Baldwin HE. The interaction between acne vulgaris and the psyche. Cutis 2002 Aug; 70 (2): 133-9PubMed

32.

Rapp DA, Brenes GA, Feldman SR, et al. Anger and acne: implications for quality of life, patient satisfaction and clinical care. Br J Dermatol 2004 Jul; 151 (1): 183-9PubMedCrossRef

33.

Tan JK. Psychosocial impact of acne vulgaris: evaluating the evidence. Skin Therapy Lett 2004; 9: 1-3PubMed

34.

Jaeschke R, Singer J, Guyatt G. Measurement of health status: ascertaining the minimal clinically important difference. Control Clin Trials 1989; 10: 407-15PubMedCrossRef

35.

Gollnick H, Cunliffe W, Berson D, et al. Management of acne: a report from a Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol 2003; 49 (1 Suppl.): S1-37PubMedCrossRef

Title: Assessing Quality of Life in Patients with Acne Vulgaris
Implications for Treatment
Author: Prof. Brigitte Dréno
Publication date: 01-04-2006
Publisher: Springer International Publishing
Published in: American Journal of Clinical Dermatology / Issue 2/2006
Print ISSN: 1175-0561
Electronic ISSN: 1179-1888
DOI: https://doi.org/10.2165/00128071-200607020-00003

At a glance: The STEP trials

Springer Medicine

Assessing Quality of Life in Patients with Acne Vulgaris

Implications for Treatment

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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