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CNS Drugs

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01-07-2006 | Adis Drug Profile

Retigabine in Partial Seizures

A Viewpoint by Emilio Perucca

Author: Emilio Perucca

Published in: CNS Drugs | Issue 7/2006

Excerpt

Most currently available antiepileptic drugs (AEDs) inhibit excessive neuronal firing by blocking voltage-dependent sodium channels or by facilitating GABAergic transmission. Because potassium channels also play a role in neuronal excitability, enhancing neuronal potassium currents provides an attractive novel mechanism for AED action. …

Bialer M, Johannessen SI, Kupferberg HJ, et al. Progress report on new antiepileptic drugs: a summary of the seventh Eilat Conference (EILAT VII). Epilepsy Res 2004; 61: 1–48PubMedCrossRef

Perucca E. The clinical pharmacology and therapeutic use of the new antiepileptic drugs. Fund Clin Pharmacol 2001; 15: 405–17CrossRef

Title: Retigabine in Partial Seizures
A Viewpoint by Emilio Perucca
Author: Emilio Perucca
Publication date: 01-07-2006
Publisher: Springer International Publishing
Published in: CNS Drugs / Issue 7/2006
Print ISSN: 1172-7047
Electronic ISSN: 1179-1934
DOI: https://doi.org/10.2165/00023210-200620070-00006

At a glance: The STEP trials

Springer Medicine

Retigabine in Partial Seizures

A Viewpoint by Emilio Perucca

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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