Skip to main content
Top
Published in: Sports Medicine 8/2003

01-07-2003 | Review Article

Exercise in Hypertension

A Clinical Review

Author: Janet P. Wallace

Published in: Sports Medicine | Issue 8/2003

Login to get access

Abstract

The current exercise prescription for the treatment of hypertension is: cardiovascular mode, for 20–60 minutes, 3–5 days per week, at 40–70% of maximum oxygen uptake (V̇O2max). Cardiovascular exercise training is the most effective mode of exercise in the prevention and treatment of hypertension. Resistance exercise is not the preferred mode of exercise treatment, but can be incorporated into an exercise regime provided the diastolic blood pressure response is within safe limits. It is inconclusive whether durations longer than 30 minutes produce significantly greater reductions in blood pressure. A frequency of three exercise sessions per week has been considered to be the minimal frequency for blood pressure reduction. Higher frequencies tended to produce greater reductions, although not significantly different. Evidence still exists that high intensity exercise (>75% V̇O2max) may not be as effective as low intensity exercise (<70% V̇O2max) in reducing elevated blood pressures. Exercise can be effective without a change in bodyweight or body fat. Bodyweight or body fat loss and anti-hypertensive medications do not have an added effect on blood pressure reduction associated with exercise. β-blockade is not the recommended anti-hypertensive medication for effective exercise performance in non-cardiac patients. Not all hypertensive patients respond to exercise treatment. Differences in genetics and pathophysiology may be responsible for the inability of some hypertensive patients to respond to exercise. Ambulatory technology may allow advances in individualising a more effective exercise prescription for low-responders and non-responders.
Literature
1.
go back to reference World Health Organization. Primary prevention of essential hypertension. World Health Organization Technical Report Series 686. Geneva: World Health Organization, 1983 World Health Organization. Primary prevention of essential hypertension. World Health Organization Technical Report Series 686. Geneva: World Health Organization, 1983
2.
3.
go back to reference Fletcher GF, Blair SN, Blumenthal J. American Heart Association. Medical statements, statement on exercise: benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology. Circulation 1992; 86: 340–4PubMedCrossRef Fletcher GF, Blair SN, Blumenthal J. American Heart Association. Medical statements, statement on exercise: benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology. Circulation 1992; 86: 340–4PubMedCrossRef
4.
go back to reference American Heart Association. Medical statements, exercise standards: a statement for health professionals from the American Heart Association. Circulation 1990; 82: 2286–322CrossRef American Heart Association. Medical statements, exercise standards: a statement for health professionals from the American Heart Association. Circulation 1990; 82: 2286–322CrossRef
5.
go back to reference American College of Sports Medicine. Position stand: physical activity, physical fitness and hypertension. Med Sci Sports Exerc 1993; 25: i–x American College of Sports Medicine. Position stand: physical activity, physical fitness and hypertension. Med Sci Sports Exerc 1993; 25: i–x
6.
go back to reference United States Department of Health and Human Services, Centers for Disease Control and Prevention, and National Center for Chronic Disease Prevention and Health Promotion, editors. Physical activity and health: a report of the surgeon general. Atlanta (GA): United States Department of Health and Human Services, 1996 United States Department of Health and Human Services, Centers for Disease Control and Prevention, and National Center for Chronic Disease Prevention and Health Promotion, editors. Physical activity and health: a report of the surgeon general. Atlanta (GA): United States Department of Health and Human Services, 1996
7.
go back to reference National Institutes of Health. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1998; 157: 2413–6 National Institutes of Health. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1998; 157: 2413–6
9.
go back to reference Martin JE, Dubbert PM. The role of exercise in prevention and moderation of blood pressure elevation. Bibl Cardiol 1987; 41: 120–42PubMed Martin JE, Dubbert PM. The role of exercise in prevention and moderation of blood pressure elevation. Bibl Cardiol 1987; 41: 120–42PubMed
10.
go back to reference Wilcox RG, Bennett T, Brown AM, et al. Is exercise good for high blood pressure? BMJ 1982; 285: 767–9PubMedCrossRef Wilcox RG, Bennett T, Brown AM, et al. Is exercise good for high blood pressure? BMJ 1982; 285: 767–9PubMedCrossRef
11.
go back to reference Kenney LW, Zambraski EJ. Physical activity in human hypertension: a mechanisms approach. Sports Med 1984; 1: 459–73PubMedCrossRef Kenney LW, Zambraski EJ. Physical activity in human hypertension: a mechanisms approach. Sports Med 1984; 1: 459–73PubMedCrossRef
12.
go back to reference Hagberg JM, Seals DR. Exercise training and hypertension. Acta Med Scand Suppl 1987; 711: 131–6 Hagberg JM, Seals DR. Exercise training and hypertension. Acta Med Scand Suppl 1987; 711: 131–6
13.
go back to reference Seals DR, Hagberg JM. The effect of exercise training on human hypertension: a review. Med Sci Sports Exerc 1984; 1: 207–15 Seals DR, Hagberg JM. The effect of exercise training on human hypertension: a review. Med Sci Sports Exerc 1984; 1: 207–15
14.
go back to reference Tipton CM. Exercise, training and hypertension. Exerc Sport Sci Rev 1984; 12: 254–306CrossRef Tipton CM. Exercise, training and hypertension. Exerc Sport Sci Rev 1984; 12: 254–306CrossRef
15.
go back to reference Tipton CM. Exercise training and hypertension: an update. In: Holloszy JO, editor. Exercise and sport sciences reviews. Baltimore (MD): Williams & Wilkins, 1991: 447–506 Tipton CM. Exercise training and hypertension: an update. In: Holloszy JO, editor. Exercise and sport sciences reviews. Baltimore (MD): Williams & Wilkins, 1991: 447–506
16.
go back to reference Fagard RH, Tipton CM. Physical activity, fitness, and hypertension. In: Bouchard C, Shephard RJ, Stephens T, editors. Physical activity, fitness, and health. Champaign (IL): Human Kinetics Publishers, 1994: 633–668 Fagard RH, Tipton CM. Physical activity, fitness, and hypertension. In: Bouchard C, Shephard RJ, Stephens T, editors. Physical activity, fitness, and health. Champaign (IL): Human Kinetics Publishers, 1994: 633–668
17.
go back to reference Whelton SP, Chin A, Xin X, et al. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med 2002; 136(7): 493–503PubMed Whelton SP, Chin A, Xin X, et al. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med 2002; 136(7): 493–503PubMed
18.
go back to reference Kelley GA, Kelley KS. Progressive resistance exercise and resting blood pressure: a meta-analysis of randomized controlled trials. Hypertension 2000; 35(3): 838–43PubMedCrossRef Kelley GA, Kelley KS. Progressive resistance exercise and resting blood pressure: a meta-analysis of randomized controlled trials. Hypertension 2000; 35(3): 838–43PubMedCrossRef
19.
go back to reference Hagberg JM, Park JJ, Brown MD. The role of exercise training in the treatment of hypertension: an update. Sports Med 2000; 30(3): 193–206PubMedCrossRef Hagberg JM, Park JJ, Brown MD. The role of exercise training in the treatment of hypertension: an update. Sports Med 2000; 30(3): 193–206PubMedCrossRef
20.
go back to reference Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc 2001; 33(6): S484–92PubMed Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc 2001; 33(6): S484–92PubMed
21.
go back to reference Petrella RJ. How effective is exercise training for the treatment of hypertension? Clin J Sport Med 1998; 8(3): 224–31PubMedCrossRef Petrella RJ. How effective is exercise training for the treatment of hypertension? Clin J Sport Med 1998; 8(3): 224–31PubMedCrossRef
22.
go back to reference Haskell WL. Health consequences of physical activity: understanding and challenges regarding dose-response. Med Sci Sports Exerc 1994; 26: 649–60PubMedCrossRef Haskell WL. Health consequences of physical activity: understanding and challenges regarding dose-response. Med Sci Sports Exerc 1994; 26: 649–60PubMedCrossRef
23.
go back to reference American College of Sports Medicine. Position stand: the recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness in healthy adults. Med Sci Sports Exerc 1990; 22: 265–74 American College of Sports Medicine. Position stand: the recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness in healthy adults. Med Sci Sports Exerc 1990; 22: 265–74
24.
go back to reference Astrand PO, Rodahl K. Textbook of work physiology. New York: McGraw-Hill Book Company, 1986 Astrand PO, Rodahl K. Textbook of work physiology. New York: McGraw-Hill Book Company, 1986
25.
go back to reference Pescatello LS, Fargo AE, Leach Jr CN, et al. Short-term effect of dynamic exercise on arterial blood pressure. Circulation 1991; 83(5): 1557–61PubMedCrossRef Pescatello LS, Fargo AE, Leach Jr CN, et al. Short-term effect of dynamic exercise on arterial blood pressure. Circulation 1991; 83(5): 1557–61PubMedCrossRef
26.
go back to reference Wallace JP, Bogle PG, King BA, et al. The magnitude and duration of ambulatory blood pressure reduction following acute exercise. J Hum Hypertens 1999; 13: 361–6PubMedCrossRef Wallace JP, Bogle PG, King BA, et al. The magnitude and duration of ambulatory blood pressure reduction following acute exercise. J Hum Hypertens 1999; 13: 361–6PubMedCrossRef
27.
go back to reference Choquette G, Furguson RJ. Blood pressure reduction in ‘borderline’ hypertensives following physical training. CMAJ 1973; 108: 699–703 Choquette G, Furguson RJ. Blood pressure reduction in ‘borderline’ hypertensives following physical training. CMAJ 1973; 108: 699–703
28.
go back to reference Connie CC, Graves JE, Pollock ML, et al. Effect of exercise training on blood pressure in 70 to 79-yr-old men and women. Med Sci Sports Exerc 1991; 23: 505–11 Connie CC, Graves JE, Pollock ML, et al. Effect of exercise training on blood pressure in 70 to 79-yr-old men and women. Med Sci Sports Exerc 1991; 23: 505–11
29.
go back to reference Gilders RM, Voner C, Dudley GA. Endurance training and blood pressure in normotensive and hypertensive adults. Med Sci Sports Exerc 1989; 21: 629–36PubMed Gilders RM, Voner C, Dudley GA. Endurance training and blood pressure in normotensive and hypertensive adults. Med Sci Sports Exerc 1989; 21: 629–36PubMed
30.
go back to reference Hagberg JM, Ehsani AA, Goldring D, et al. Effect of weight training on blood pressure and hemodynamics in hypertensive adolescents. J Pediatr 1984; 104: 147–51PubMedCrossRef Hagberg JM, Ehsani AA, Goldring D, et al. Effect of weight training on blood pressure and hemodynamics in hypertensive adolescents. J Pediatr 1984; 104: 147–51PubMedCrossRef
31.
go back to reference Hagberg JM, Montain SJ, Martin WH. Blood pressure and hemodynamic responses after exercise in older hypertensives. J Appl Physiol 1987; 63: 270–6PubMed Hagberg JM, Montain SJ, Martin WH. Blood pressure and hemodynamic responses after exercise in older hypertensives. J Appl Physiol 1987; 63: 270–6PubMed
32.
go back to reference Marceau M, Kouame N, Lacourciere Y, et al. Effects of different training intensities on 24-hour blood pressure in hypertensive subjects. Circulation 1993; 88: 2803–11PubMedCrossRef Marceau M, Kouame N, Lacourciere Y, et al. Effects of different training intensities on 24-hour blood pressure in hypertensive subjects. Circulation 1993; 88: 2803–11PubMedCrossRef
33.
go back to reference Van Hoof R, Hespel P, Fagand R, et al. Effects of endurance training on blood pressure at rest, during exercise and during 24 hours in sedentary men. Am J Cardiol 1989; 63: 945–9PubMedCrossRef Van Hoof R, Hespel P, Fagand R, et al. Effects of endurance training on blood pressure at rest, during exercise and during 24 hours in sedentary men. Am J Cardiol 1989; 63: 945–9PubMedCrossRef
34.
go back to reference Moreau KL. Increased daily walking lowers blood pressure in postmenopausal women. Med Sci Sports Exerc 2001; 33: 1825–31PubMedCrossRef Moreau KL. Increased daily walking lowers blood pressure in postmenopausal women. Med Sci Sports Exerc 2001; 33: 1825–31PubMedCrossRef
35.
go back to reference Kenney MJ, Seals DR. Postexercise hypotension. Key features, mechanisms, and clinical significance. Hypertension 1993; 22: 635–64CrossRef Kenney MJ, Seals DR. Postexercise hypotension. Key features, mechanisms, and clinical significance. Hypertension 1993; 22: 635–64CrossRef
36.
go back to reference Blair SN, Kohl III HW, Paffenbarger Jr RS, et al. Physical fitness and all-cause mortality: a prospective study of healthy men and women. JAMA 1989; 262: 2395–401PubMedCrossRef Blair SN, Kohl III HW, Paffenbarger Jr RS, et al. Physical fitness and all-cause mortality: a prospective study of healthy men and women. JAMA 1989; 262: 2395–401PubMedCrossRef
37.
go back to reference American College of Sports Medicine. Guidelines for exercise testing and prescription. 3rd ed. Philadelphia (PA): Lea & Febiger, 1986 American College of Sports Medicine. Guidelines for exercise testing and prescription. 3rd ed. Philadelphia (PA): Lea & Febiger, 1986
38.
go back to reference Fardy PS. Isometric exercise and the cardiovascular system. Phys Sportsmed 1981; 9: 43–53 Fardy PS. Isometric exercise and the cardiovascular system. Phys Sportsmed 1981; 9: 43–53
39.
go back to reference Kenney LW, editor. 40. ACSM’s guidelines for exercise testing and prescription. 6th ed. Philadelphia (PA): Lippencott, Williams & Wilkins, 2000 Kenney LW, editor. 40. ACSM’s guidelines for exercise testing and prescription. 6th ed. Philadelphia (PA): Lippencott, Williams & Wilkins, 2000
40.
go back to reference Inbar G, Wallace JP, Jastremski C. Interaction of intensity and duration on acute postexercise blood pressure reduction [abstract]. J Cardiopulm Rehabil 1991; 11: 320CrossRef Inbar G, Wallace JP, Jastremski C. Interaction of intensity and duration on acute postexercise blood pressure reduction [abstract]. J Cardiopulm Rehabil 1991; 11: 320CrossRef
41.
go back to reference Jennings G, Nelson L, Nestel P, et al. The effects of changes in physical activity on major cardiovascular risk factors, hemodynamics, sympathetic function, and glucose utilization in man: a controlled study of four levels of activity. Circulation 1986; 73: 30–40PubMedCrossRef Jennings G, Nelson L, Nestel P, et al. The effects of changes in physical activity on major cardiovascular risk factors, hemodynamics, sympathetic function, and glucose utilization in man: a controlled study of four levels of activity. Circulation 1986; 73: 30–40PubMedCrossRef
42.
go back to reference MacDonald JR, MacDougall JD, Hogben CD. The effects of exercise duration on post-exercise hypotension. J Hum Hypertens 2000; 14: 125–9PubMedCrossRef MacDonald JR, MacDougall JD, Hogben CD. The effects of exercise duration on post-exercise hypotension. J Hum Hypertens 2000; 14: 125–9PubMedCrossRef
43.
go back to reference Nelson L, Jennings GL, Esler MD, et al. Effect of changing levels of physical activity on blood-pressure and haemodynamics in essential hypertension. Lancet 1986; II: 473–6CrossRef Nelson L, Jennings GL, Esler MD, et al. Effect of changing levels of physical activity on blood-pressure and haemodynamics in essential hypertension. Lancet 1986; II: 473–6CrossRef
44.
go back to reference Posner JD, Gorman KM, Windsor-Landsberg L, et al. Low to moderate intensity endurance training in healthy older adults: physiological responses after four months. J Am Geriatr Soc 1992; 40: 1–7PubMed Posner JD, Gorman KM, Windsor-Landsberg L, et al. Low to moderate intensity endurance training in healthy older adults: physiological responses after four months. J Am Geriatr Soc 1992; 40: 1–7PubMed
45.
go back to reference Okumiya K, Matsubayashi K, Wada T, et al. Effects of exercise on neurobehavioral function in community-dwelling older people more than 75 years of age. J Am Geriatr Soc 1996; 44: 569–72PubMed Okumiya K, Matsubayashi K, Wada T, et al. Effects of exercise on neurobehavioral function in community-dwelling older people more than 75 years of age. J Am Geriatr Soc 1996; 44: 569–72PubMed
46.
go back to reference Hagberg JM, Montain SJ, Martin III WH, et al. Effect of exercise training in 60–69 year-old persons with essential hypertension. Am J Cardiol 1989; 4: 348–53CrossRef Hagberg JM, Montain SJ, Martin III WH, et al. Effect of exercise training in 60–69 year-old persons with essential hypertension. Am J Cardiol 1989; 4: 348–53CrossRef
47.
go back to reference Tashiro E, Miura W, Koga M. Crossover comparison between the depressor effects of low and high work rate exercise in mild hypertension. Clin Exp Pharmacol Physiol 1993; 20: 689–96PubMedCrossRef Tashiro E, Miura W, Koga M. Crossover comparison between the depressor effects of low and high work rate exercise in mild hypertension. Clin Exp Pharmacol Physiol 1993; 20: 689–96PubMedCrossRef
48.
go back to reference Rogers MW, Probst MM, Gruber JJ, et al. Differential effects of exercise training intensity on blood pressure and cardiovascular responses to stress in borderline hypertensive humans. J Hypertens 1966; 14: 1369–75CrossRef Rogers MW, Probst MM, Gruber JJ, et al. Differential effects of exercise training intensity on blood pressure and cardiovascular responses to stress in borderline hypertensive humans. J Hypertens 1966; 14: 1369–75CrossRef
49.
go back to reference Moreira WD, Fuchs FD, Ribeiro JP, et al. The effects of two aerobic training intensities on ambulatory blood pressure in hypertensive patients: results of randomized trial. J Clin Epidemiol 1999; 52: 637–42PubMedCrossRef Moreira WD, Fuchs FD, Ribeiro JP, et al. The effects of two aerobic training intensities on ambulatory blood pressure in hypertensive patients: results of randomized trial. J Clin Epidemiol 1999; 52: 637–42PubMedCrossRef
50.
go back to reference Matsusaki M, Ikeda M, Tashiro E. Influence of work load of aerobic exercise in hypertension. Circulation 1992; 19: 471–9 Matsusaki M, Ikeda M, Tashiro E. Influence of work load of aerobic exercise in hypertension. Circulation 1992; 19: 471–9
51.
go back to reference Tipton CM, Matthes RD, Marcus KD, et al. Influences of exercise intensity, age, and medication on resting systolic blood pressure of SHR populations. J Appl Physiol 1983; 55: 1305–10PubMed Tipton CM, Matthes RD, Marcus KD, et al. Influences of exercise intensity, age, and medication on resting systolic blood pressure of SHR populations. J Appl Physiol 1983; 55: 1305–10PubMed
52.
go back to reference Panel E. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. Arch Intern Med 1998; 158: 1855–67CrossRef Panel E. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. Arch Intern Med 1998; 158: 1855–67CrossRef
53.
go back to reference Blair D, Habicht JP, Sims EA, et al. Evidence for an increased risk for hypertension with centrally located body fat and the effect of race and sex on this risk. Am J Epidemiol 1984; 119: 526–40PubMed Blair D, Habicht JP, Sims EA, et al. Evidence for an increased risk for hypertension with centrally located body fat and the effect of race and sex on this risk. Am J Epidemiol 1984; 119: 526–40PubMed
54.
go back to reference Hartz AJ, Rupley DC, Rimm AA. The association of girth measurements with disease in 32,856 women. Am J Epidemiol 1984; 119: 71–80PubMed Hartz AJ, Rupley DC, Rimm AA. The association of girth measurements with disease in 32,856 women. Am J Epidemiol 1984; 119: 71–80PubMed
55.
go back to reference Iso H, Kiyama M, Naito Y, et al. The relation of body fat distribution and body mass index with haemoglobin Alc, blood pressure and blood lipids in urban Japanese men. Int J Epidemiol 1991; 20: 88–94PubMedCrossRef Iso H, Kiyama M, Naito Y, et al. The relation of body fat distribution and body mass index with haemoglobin Alc, blood pressure and blood lipids in urban Japanese men. Int J Epidemiol 1991; 20: 88–94PubMedCrossRef
56.
go back to reference Kalkhoff RK, Hartz AH, Rupley D, et al. Relationship of body fat distribution to blood pressure, carbohydrate tolerance, and plasma lipids in healthy obese women. J Lab Clin Med 1983; 102: 621–7PubMed Kalkhoff RK, Hartz AH, Rupley D, et al. Relationship of body fat distribution to blood pressure, carbohydrate tolerance, and plasma lipids in healthy obese women. J Lab Clin Med 1983; 102: 621–7PubMed
57.
go back to reference Dengel DR, Galecki AT, Hagberg JM, et al. The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. Am J Hypertens 1998; 11(12): 1405–2PubMedCrossRef Dengel DR, Galecki AT, Hagberg JM, et al. The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. Am J Hypertens 1998; 11(12): 1405–2PubMedCrossRef
58.
go back to reference Gordon NF, Scott CB, Levine BD. Comparison of single vs multiple lifestyle interventions: are the antihypertensive effects of exericse training and diet-induced wieght loss additive? Am J Cardiol 1997; 79(6): 763–7PubMedCrossRef Gordon NF, Scott CB, Levine BD. Comparison of single vs multiple lifestyle interventions: are the antihypertensive effects of exericse training and diet-induced wieght loss additive? Am J Cardiol 1997; 79(6): 763–7PubMedCrossRef
59.
go back to reference American College of Sports Medicine: appropriate intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 2001; 33(12): 2145–56 American College of Sports Medicine: appropriate intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 2001; 33(12): 2145–56
60.
go back to reference Bouchard C, Rankinen T. Individual differences in response to regular physical activity. Med Sci Sports Exerc 2001; 33 (6 Suppl.): S446–51PubMed Bouchard C, Rankinen T. Individual differences in response to regular physical activity. Med Sci Sports Exerc 2001; 33 (6 Suppl.): S446–51PubMed
61.
go back to reference Kinoshita A, Urata H, Tanabe Y. What types of hypertensives respond better to mild exercise therapy. J Hypertens 1988; 6Suppl. 4: S631–3 Kinoshita A, Urata H, Tanabe Y. What types of hypertensives respond better to mild exercise therapy. J Hypertens 1988; 6Suppl. 4: S631–3
62.
go back to reference Pescatello LS, Kulikowich JM. The after effects of dynamic exercise on ambulatory blood pressure. Med Sci Sports Exerc 2001; 33: 1855–1PubMedCrossRef Pescatello LS, Kulikowich JM. The after effects of dynamic exercise on ambulatory blood pressure. Med Sci Sports Exerc 2001; 33: 1855–1PubMedCrossRef
63.
go back to reference Wallace JP, Inbar G, Stager JM, et al. Hemodynamic determinants of blood pressure reduction following exercise [abstract]. J Cardiopulm Rehabil 1995; 15: 361 Wallace JP, Inbar G, Stager JM, et al. Hemodynamic determinants of blood pressure reduction following exercise [abstract]. J Cardiopulm Rehabil 1995; 15: 361
64.
go back to reference Ades PA, Gunther PG, Meyer WL, et al. Cardiac and skeletal muscle adaptations to training in systemic hypertension and effects of beta blockade (metoprolol and propranolol). Am J Cardiol 1990; 66(5): 591–6PubMedCrossRef Ades PA, Gunther PG, Meyer WL, et al. Cardiac and skeletal muscle adaptations to training in systemic hypertension and effects of beta blockade (metoprolol and propranolol). Am J Cardiol 1990; 66(5): 591–6PubMedCrossRef
65.
go back to reference Nami R, Mondillo S, Agricola E, et al. Aerobic exercise training fails to reduce blood pressure in nondipper-type hypertension. Am J Hypertens 2000; 13: 593–600PubMedCrossRef Nami R, Mondillo S, Agricola E, et al. Aerobic exercise training fails to reduce blood pressure in nondipper-type hypertension. Am J Hypertens 2000; 13: 593–600PubMedCrossRef
66.
go back to reference Jennings G, Nelson L, Dewar E. Antihypertensive and haemodynamic effects of one year’s regular exercise. J Hypertens 1986; 4Suppl. 6: S659–61 Jennings G, Nelson L, Dewar E. Antihypertensive and haemodynamic effects of one year’s regular exercise. J Hypertens 1986; 4Suppl. 6: S659–61
67.
go back to reference Reiling MJ, Clayton-Bare LA, Chase PB, et al. Effects of low-level exercise training (et) on resting and ambulatory blood pressure (bp) in older persons with hypertension [abstract]. Physiologist 1988; 31: A158 Reiling MJ, Clayton-Bare LA, Chase PB, et al. Effects of low-level exercise training (et) on resting and ambulatory blood pressure (bp) in older persons with hypertension [abstract]. Physiologist 1988; 31: A158
68.
go back to reference Reiling MJ, Bare LA, Chase PB, et al. Influence of regular exercise on 24-hour blood pressure (BP24) in middle aged and older persons with mild essential hypertension (EH). Med Sci Sports Exerc 1990; 22: S48 Reiling MJ, Bare LA, Chase PB, et al. Influence of regular exercise on 24-hour blood pressure (BP24) in middle aged and older persons with mild essential hypertension (EH). Med Sci Sports Exerc 1990; 22: S48
69.
go back to reference DePlaen JE, Detry JM. Hemodynamic effects of physical training in established arterial hypertension. Acta Cardiol 1980; 35: 179–88 DePlaen JE, Detry JM. Hemodynamic effects of physical training in established arterial hypertension. Acta Cardiol 1980; 35: 179–88
70.
go back to reference Johnson WP, Grover JA. Hemodynamic and metabolic effects of physical training in four patients with essential hypertension. CMAJ 1967; 96: 842–7 Johnson WP, Grover JA. Hemodynamic and metabolic effects of physical training in four patients with essential hypertension. CMAJ 1967; 96: 842–7
71.
go back to reference Nomura G, Kumagai K, Tidonkhwa K, et al. Physical training in essential hypertension: alone and in combination with dietary salt restriction. J Cardiac Rehabil 1984; 4: 469–75 Nomura G, Kumagai K, Tidonkhwa K, et al. Physical training in essential hypertension: alone and in combination with dietary salt restriction. J Cardiac Rehabil 1984; 4: 469–75
72.
go back to reference Urata H, Tanabe Y, Kiyonaga A, et al. Antihypertensive and volume-depleting effects of mild exercise on essential hypertension. Hypertension 1987; 9: 245–52PubMedCrossRef Urata H, Tanabe Y, Kiyonaga A, et al. Antihypertensive and volume-depleting effects of mild exercise on essential hypertension. Hypertension 1987; 9: 245–52PubMedCrossRef
73.
go back to reference Bogle PG, Wallace JP, Jastremski C. Immediate post-exercise hemodynamic changes in hypertensive adults [abstract]. Med Sci Sports Exerc 1998; 30Suppl. 5: S241 Bogle PG, Wallace JP, Jastremski C. Immediate post-exercise hemodynamic changes in hypertensive adults [abstract]. Med Sci Sports Exerc 1998; 30Suppl. 5: S241
74.
go back to reference Rankinen T, Rice T, Perusse L, et al. NOS3 Glu298Asp genotype and blood pressure response to endurance training: The HERITAGE Family Study. Hypertension 2000; 36(5): 885–9PubMedCrossRef Rankinen T, Rice T, Perusse L, et al. NOS3 Glu298Asp genotype and blood pressure response to endurance training: The HERITAGE Family Study. Hypertension 2000; 36(5): 885–9PubMedCrossRef
75.
go back to reference Rankinen T, An P, Rice T, et al. Genomic scan for exercise blood pressure in health, risk factors, exercise training and genetics (HERITAGE) Family Study. Hypertension 2001; 38(1): 30–7PubMedCrossRef Rankinen T, An P, Rice T, et al. Genomic scan for exercise blood pressure in health, risk factors, exercise training and genetics (HERITAGE) Family Study. Hypertension 2001; 38(1): 30–7PubMedCrossRef
76.
go back to reference Rice T, Rankinen T, Chagnon YC, et al. Genomewide linkage scan of resting blood pressure: HERITAGE Family Study. Hypertension 2002; 39(6): 1037–43PubMedCrossRef Rice T, Rankinen T, Chagnon YC, et al. Genomewide linkage scan of resting blood pressure: HERITAGE Family Study. Hypertension 2002; 39(6): 1037–43PubMedCrossRef
77.
go back to reference Rice T, An P, Gagnon J, et al. Heritability of HR and BP response to exercise training in the HERITAGE Family Study. Med Sci Sports Exerc 2002; 34(6): 972–9PubMedCrossRef Rice T, An P, Gagnon J, et al. Heritability of HR and BP response to exercise training in the HERITAGE Family Study. Med Sci Sports Exerc 2002; 34(6): 972–9PubMedCrossRef
78.
go back to reference Hagberg JM, Ferrell RE, Dengel DR, et al. Exercise training-induced blood pressure and plasma lipid improvements in hypertensives may be genotype dependent. Hypertension 1999; 34(1): 18–23PubMedCrossRef Hagberg JM, Ferrell RE, Dengel DR, et al. Exercise training-induced blood pressure and plasma lipid improvements in hypertensives may be genotype dependent. Hypertension 1999; 34(1): 18–23PubMedCrossRef
79.
go back to reference Wilmore JH, Stanforth PR, Gagnon J, et al. Heart rate and blood pressure changes with endurance training: The HERITAGE Family Study. Med Sci Sports Exerc 2001; 33(1): 107–16PubMed Wilmore JH, Stanforth PR, Gagnon J, et al. Heart rate and blood pressure changes with endurance training: The HERITAGE Family Study. Med Sci Sports Exerc 2001; 33(1): 107–16PubMed
80.
go back to reference Kelemen MH, Effron MB, Valenti SA, et al. Exercise training combined with antihypertensive drug therapy. Effects on lipids, blood pressure, and left ventricular mass. JAMA 1990; 263: 2766–71PubMedCrossRef Kelemen MH, Effron MB, Valenti SA, et al. Exercise training combined with antihypertensive drug therapy. Effects on lipids, blood pressure, and left ventricular mass. JAMA 1990; 263: 2766–71PubMedCrossRef
81.
go back to reference Stewart KJ, Effron MB, Valenti SA, et al. Effects of diltiazem or propranolol during exercise training of hypertensive men. Med Sci Sports Exerc 1990; 22: 171–7PubMed Stewart KJ, Effron MB, Valenti SA, et al. Effects of diltiazem or propranolol during exercise training of hypertensive men. Med Sci Sports Exerc 1990; 22: 171–7PubMed
82.
go back to reference Gordon NF, Duncan JJ. Effect of beta-blockers on exercise physiology: implications for exercise training. Med Sci Sports Exerc 1991; 23: 668–76PubMed Gordon NF, Duncan JJ. Effect of beta-blockers on exercise physiology: implications for exercise training. Med Sci Sports Exerc 1991; 23: 668–76PubMed
83.
go back to reference Duncan JJ, Vaandrager H, Farr JE. Effect of intrinsic sympathomimetic activity on serum lipids during exercise training in hypertensive patients receiving chronic B-Blocker therapy. J Cardiopulm Rehabil 1989; 9: 110–4CrossRef Duncan JJ, Vaandrager H, Farr JE. Effect of intrinsic sympathomimetic activity on serum lipids during exercise training in hypertensive patients receiving chronic B-Blocker therapy. J Cardiopulm Rehabil 1989; 9: 110–4CrossRef
84.
go back to reference Chick TW, Halperin AK, Gacek EM. Effect of antihypertensive medications on exercise performance: a review. Med Sci Sports Exerc 1988; 20: 447–54PubMed Chick TW, Halperin AK, Gacek EM. Effect of antihypertensive medications on exercise performance: a review. Med Sci Sports Exerc 1988; 20: 447–54PubMed
85.
go back to reference Pool PE, Seagren SC, Salel AF, et al. Effects of diltiazem on serum lipids, exercise performance and blood pressure: randomized, double-blind, placebo-controlled evaluation for systemic hypertension. Am J Cardiol 1985; 56: 86H–91HPubMedCrossRef Pool PE, Seagren SC, Salel AF, et al. Effects of diltiazem on serum lipids, exercise performance and blood pressure: randomized, double-blind, placebo-controlled evaluation for systemic hypertension. Am J Cardiol 1985; 56: 86H–91HPubMedCrossRef
86.
go back to reference Sommers VK, Conway J, Coats A, et al. Postexercise hypotension is not sustained in normal and hypertensive humans. Hypertension 1991; 18: 211–5CrossRef Sommers VK, Conway J, Coats A, et al. Postexercise hypotension is not sustained in normal and hypertensive humans. Hypertension 1991; 18: 211–5CrossRef
87.
go back to reference Roltsch MH. Acute resistive exercise does not affect ambulatory blood pressure in young adult men and women. Med Sci Sports Exerc 2001; 33: 881–6PubMedCrossRef Roltsch MH. Acute resistive exercise does not affect ambulatory blood pressure in young adult men and women. Med Sci Sports Exerc 2001; 33: 881–6PubMedCrossRef
88.
go back to reference Southard DR, Hart L. Case report: the influence on blood pressure during daily activities of a single session of aerobic exercise. Behav Med 1991; 17(3): 135–42PubMedCrossRef Southard DR, Hart L. Case report: the influence on blood pressure during daily activities of a single session of aerobic exercise. Behav Med 1991; 17(3): 135–42PubMedCrossRef
89.
go back to reference Blumenthal JA, Siegel WC, Appelbaum M. Failure of exercise to reduce blood pressure in patients with mild hypertension. JAMA 1991; 266: 2098–104PubMedCrossRef Blumenthal JA, Siegel WC, Appelbaum M. Failure of exercise to reduce blood pressure in patients with mild hypertension. JAMA 1991; 266: 2098–104PubMedCrossRef
90.
go back to reference White WB. Analysis of ambulatory blood pressure data in antihypertensive drug trials. J Hypertens 1991;9Suppl. 1: S27–32 White WB. Analysis of ambulatory blood pressure data in antihypertensive drug trials. J Hypertens 1991;9Suppl. 1: S27–32
91.
go back to reference Pickering TG. Clinical applications of ambulatory blood pressure monitoring: the white coat syndrome. Clin Invest Med 1991; 14: 212–7PubMed Pickering TG. Clinical applications of ambulatory blood pressure monitoring: the white coat syndrome. Clin Invest Med 1991; 14: 212–7PubMed
92.
go back to reference Staessen JA, Thijs L, Fagard R, et al. Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. JAMA 1999; 282: 539–46PubMedCrossRef Staessen JA, Thijs L, Fagard R, et al. Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. JAMA 1999; 282: 539–46PubMedCrossRef
93.
go back to reference Materson BJ, Preston RA. Classic therapeutic trials in hypertension: were patients vulnerable to unsuppressed peak morning blood pressure? Am J Hypertens 1991; 4: 449S–53SPubMed Materson BJ, Preston RA. Classic therapeutic trials in hypertension: were patients vulnerable to unsuppressed peak morning blood pressure? Am J Hypertens 1991; 4: 449S–53SPubMed
94.
go back to reference Park S, Lehmkuhl LA, Tanner DA, et al. Effects of exercise treatment on ambulatory blood pressure and diurnal variation in nocturnal nondipping hypertension [abstract]. Med Sci Sports Exerc 2002; 34: S12 Park S, Lehmkuhl LA, Tanner DA, et al. Effects of exercise treatment on ambulatory blood pressure and diurnal variation in nocturnal nondipping hypertension [abstract]. Med Sci Sports Exerc 2002; 34: S12
95.
go back to reference Wallace JP, Park SJ, Lehmkuhl LA, et al. Do nocturnal dippers and non-dippers respond similarly to exercise treatment for hypertension? Med Sci Sports Exerc. In press Wallace JP, Park SJ, Lehmkuhl LA, et al. Do nocturnal dippers and non-dippers respond similarly to exercise treatment for hypertension? Med Sci Sports Exerc. In press
96.
go back to reference Park SJ, Black KN, Weaver VR, et al. Is evening exercise more effective than evening exercise in reducing blood pressure in nocturnal non-dipping hypertension [abstract]. Med Sci Sports Exerc. 2003; 35: S174 Park SJ, Black KN, Weaver VR, et al. Is evening exercise more effective than evening exercise in reducing blood pressure in nocturnal non-dipping hypertension [abstract]. Med Sci Sports Exerc. 2003; 35: S174
Metadata
Title
Exercise in Hypertension
A Clinical Review
Author
Janet P. Wallace
Publication date
01-07-2003
Publisher
Springer International Publishing
Published in
Sports Medicine / Issue 8/2003
Print ISSN: 0112-1642
Electronic ISSN: 1179-2035
DOI
https://doi.org/10.2165/00007256-200333080-00004

Other articles of this Issue 8/2003

Sports Medicine 8/2003 Go to the issue