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Published in: Sports Medicine 3/2002

01-03-2002 | Leading Article

Ethics in Exercise Science Research

Author: Roy J. Shephard

Published in: Sports Medicine | Issue 3/2002

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Abstract

Ethical evaluation is a vital but sometimes neglected component of research policy in the exercise sciences. This article reviews some issues in human research, with particular reference to studies undertaken by the exercise scientist. The typical composition and functions of the research review committee are examined in the context of individual and institutional ethical norms. In multicentre trials, there are often problems in coordinating ethical approval between institutions. On-going monitoring of research may have value in the detection of fraud. A reduction in the secrecy of committee proceedings would allow a closer auditing of the research review process. Authors need to give more thought to developing appropriate research questions. Scarce resources may be wasted because of inappropriate study design or an inadequate statistical analysis of the results. The costs of any proposed investigation must be weighed carefully against possible benefits. Confidentiality is particularly important when collecting data at the worksite or over the internet. Informed consent should be based on a full disclosure of risks; the participant should be competent to understand the nature and magnitude of these risks, and undue pressure to participate in an experiment must be avoided. The opposition to placebo trials expressed in the Declaration of Helsinki requires careful consideration of the use of control groups, since regular exercise is known to benefit health. If research is conducted in under-developed societies, the standards of treatment of the participants should match those expected in developed societies. The publication of findings must be fair and well balanced; examples of fraud and misconduct continue to be reported. Some journals apparently still publish papers, even if they have not received an initial institutional review. Editors should restore meaning to the word ‘author’, avoid the bias to a publication of ‘positive’ results, limit the impact of commercial sponsorship on reporting and curtail the current trend to redundant presentations and publications. Development of academic courses in research ethics may help to avoid some of these abuses.
Literature
1.
go back to reference Onions CT, editor. Shorter Oxford dictionary. 3rd ed. Oxford: Clarendon Press, 1964 Onions CT, editor. Shorter Oxford dictionary. 3rd ed. Oxford: Clarendon Press, 1964
2.
go back to reference Kant I, Heath PL, Schneewind JB, editors. Lectures on ethics. Translated by Heath PL. New York (NY): Cambridge University Press, 1997 Kant I, Heath PL, Schneewind JB, editors. Lectures on ethics. Translated by Heath PL. New York (NY): Cambridge University Press, 1997
3.
go back to reference Mill JS. Utilitarianism. New York (NY): Longmans Green, 1907 Mill JS. Utilitarianism. New York (NY): Longmans Green, 1907
5.
6.
go back to reference Reich WT. Encyclopedia of bioethics. New York (NY): Simon and Schuster MacMillan, 1995 Reich WT. Encyclopedia of bioethics. New York (NY): Simon and Schuster MacMillan, 1995
7.
go back to reference World Medical Association. Human experimentation: code of ethics of the World Medical Association. BMJ 1964; II: 177 World Medical Association. Human experimentation: code of ethics of the World Medical Association. BMJ 1964; II: 177
8.
9.
go back to reference World Medical Association. Ethical principles for medical research involving human subjects. Geneva:World Medical Association, 2000 World Medical Association. Ethical principles for medical research involving human subjects. Geneva:World Medical Association, 2000
10.
go back to reference Cruess RL, Cruess SR. Professionalism, laws and kings. Clin Invest Med 1997; 20: 407–13PubMed Cruess RL, Cruess SR. Professionalism, laws and kings. Clin Invest Med 1997; 20: 407–13PubMed
11.
go back to reference Medical Research Council. Guidelines on research involving human subjects. Ottawa (ON): Medical Research Council, 1987 Medical Research Council. Guidelines on research involving human subjects. Ottawa (ON): Medical Research Council, 1987
12.
go back to reference Tricouncil Working Group. Code of conduct for research involving humans. Ottawa (ON): Department of Supply and Services, 1996 Tricouncil Working Group. Code of conduct for research involving humans. Ottawa (ON): Department of Supply and Services, 1996
13.
go back to reference Canadian Medical Association. Code of ethics of the Canadian Medical Association. Ottawa (ON): Canadian Medical Association, 1996 Canadian Medical Association. Code of ethics of the Canadian Medical Association. Ottawa (ON): Canadian Medical Association, 1996
14.
go back to reference Kenny NP. The CMA code of ethics: more room for reflection. Can Med Assoc J 1996; 155: 1063–5 Kenny NP. The CMA code of ethics: more room for reflection. Can Med Assoc J 1996; 155: 1063–5
15.
go back to reference Ruyter KW. Medical research ethics 50 years after Nuremberg. Tidsskr Nor Laegeforen 1997; 117: 4383–91PubMed Ruyter KW. Medical research ethics 50 years after Nuremberg. Tidsskr Nor Laegeforen 1997; 117: 4383–91PubMed
16.
go back to reference Baum M. Education and debate: Declaration of Helsinki should be strengthened. BMJ 2000; 321: 442–5CrossRef Baum M. Education and debate: Declaration of Helsinki should be strengthened. BMJ 2000; 321: 442–5CrossRef
17.
go back to reference Rothman KJ, Michels KB. Education and debate: Declaration of Helsinki should be strengthened. BMJ 2000; 321: 442–5PubMedCrossRef Rothman KJ, Michels KB. Education and debate: Declaration of Helsinki should be strengthened. BMJ 2000; 321: 442–5PubMedCrossRef
18.
go back to reference Veatch R. Medical codes and oaths. In: Reich W, editor. Encyclopedia of bioethics. Vol. 3. New York (NY): Simon Schuster MacMillan, 1995: 1419–35 Veatch R. Medical codes and oaths. In: Reich W, editor. Encyclopedia of bioethics. Vol. 3. New York (NY): Simon Schuster MacMillan, 1995: 1419–35
19.
go back to reference Dickens BM. Human research beyond the medical model: legal and ethical issues. Med Law 1997; 16: 687–703PubMed Dickens BM. Human research beyond the medical model: legal and ethical issues. Med Law 1997; 16: 687–703PubMed
20.
go back to reference American College of Sports Medicine. Policy statement regarding the use of human subjects and informed consent. Med Sci Sports Exerc 2000; 32: vi American College of Sports Medicine. Policy statement regarding the use of human subjects and informed consent. Med Sci Sports Exerc 2000; 32: vi
21.
go back to reference American Psychological Association. Ethical principles in the conduct of research with human participants. Washington, DC: American Psychological Association, 1982CrossRef American Psychological Association. Ethical principles in the conduct of research with human participants. Washington, DC: American Psychological Association, 1982CrossRef
22.
go back to reference American College of Sports Medicine. Code of ethics. Indianapolis (IN): American College of Sports Medicine, 2001 American College of Sports Medicine. Code of ethics. Indianapolis (IN): American College of Sports Medicine, 2001
23.
go back to reference American College of Sports Medicine. ACSM’s guidelines for exercise testing and prescription. 6th ed. Philadelphia (PA): Lippincott, Williams and Wilkins, 2000 American College of Sports Medicine. ACSM’s guidelines for exercise testing and prescription. 6th ed. Philadelphia (PA): Lippincott, Williams and Wilkins, 2000
25.
go back to reference Shephard RJ. Ethical considerations in human experimentation. Can Assoc Health Phys Exerc Recreation J 1967; 33: 13–6 Shephard RJ. Ethical considerations in human experimentation. Can Assoc Health Phys Exerc Recreation J 1967; 33: 13–6
26.
go back to reference Shephard RJ. Alive, man: the physiology of physical activity. Springfield (IL): CC Thomas, 1972 Shephard RJ. Alive, man: the physiology of physical activity. Springfield (IL): CC Thomas, 1972
27.
go back to reference Kent G. The views of members of local research ethics committees, researchers, and members of the public towards the roles and functions of LRECs. J Med Ethics 1997; 23: 186–90PubMedCrossRef Kent G. The views of members of local research ethics committees, researchers, and members of the public towards the roles and functions of LRECs. J Med Ethics 1997; 23: 186–90PubMedCrossRef
28.
go back to reference Weijer C, Dickens B, Meslin EM. Bioethics for clinicians: 10. Research ethics. Can Med Assoc J 1997; 156: 1153–7 Weijer C, Dickens B, Meslin EM. Bioethics for clinicians: 10. Research ethics. Can Med Assoc J 1997; 156: 1153–7
29.
go back to reference Coker R, McKee M. Ethical approval for health research in central and eastern Europe: an international survey. Clin Med 2001; 1: 197–9PubMed Coker R, McKee M. Ethical approval for health research in central and eastern Europe: an international survey. Clin Med 2001; 1: 197–9PubMed
30.
go back to reference Lynoe N, Sandlund M, Jacobsson L. Research ethics committees: a comparative study of assessment of ethical dilemmas. Scand J Public Health 1999; 27: 152–9PubMedCrossRef Lynoe N, Sandlund M, Jacobsson L. Research ethics committees: a comparative study of assessment of ethical dilemmas. Scand J Public Health 1999; 27: 152–9PubMedCrossRef
31.
go back to reference DeRenzo EG. Power differentials, context, relationship, and emotions: feminist ethics considerations and human subjects research. J Womens Health 1998; 7: 971–7PubMedCrossRef DeRenzo EG. Power differentials, context, relationship, and emotions: feminist ethics considerations and human subjects research. J Womens Health 1998; 7: 971–7PubMedCrossRef
32.
go back to reference Berk RA, Korenman SG, Wenger NS. Measuring consensus about scientific research norms. Sci Eng Ethics 2000; 6: 315–40PubMedCrossRef Berk RA, Korenman SG, Wenger NS. Measuring consensus about scientific research norms. Sci Eng Ethics 2000; 6: 315–40PubMedCrossRef
33.
go back to reference Wenger NS, Korenman SG, Berk R, et al. The ethics of scientific research: an analysis of focus groups of scientists and institutional representatives. J Investig Med 1997; 45: 371–80PubMed Wenger NS, Korenman SG, Berk R, et al. The ethics of scientific research: an analysis of focus groups of scientists and institutional representatives. J Investig Med 1997; 45: 371–80PubMed
34.
go back to reference Price JH, Dake JA, Islam R. Selected ethical issues in research and publication: perceptions of health education faculty. Health Educ Behav 2001; 28: 51–64PubMedCrossRef Price JH, Dake JA, Islam R. Selected ethical issues in research and publication: perceptions of health education faculty. Health Educ Behav 2001; 28: 51–64PubMedCrossRef
35.
go back to reference Blunt J, Watson AJM. Meeting the challenges facing research ethics committees: some practical suggestions. BMJ 1998; 316: 58–61PubMedCrossRef Blunt J, Watson AJM. Meeting the challenges facing research ethics committees: some practical suggestions. BMJ 1998; 316: 58–61PubMedCrossRef
36.
go back to reference Lux AL, Edwards SW, Osborne JP. Responses of local research ethics committees to a study with approval froma multicentre research ethics committee. BMJ 2000; 320: 1182–3PubMedCrossRef Lux AL, Edwards SW, Osborne JP. Responses of local research ethics committees to a study with approval froma multicentre research ethics committee. BMJ 2000; 320: 1182–3PubMedCrossRef
37.
go back to reference Alberti KGM. Multicentre research ethics committees: has the cure been worse than the disease? BMJ 2000; 320: 1157–8PubMedCrossRef Alberti KGM. Multicentre research ethics committees: has the cure been worse than the disease? BMJ 2000; 320: 1157–8PubMedCrossRef
38.
go back to reference McCusker J, Kruszewski Z, Lacey B, et al. Monitoring clinical research: report of one hospital’s experience. Can Med Assoc J 2001; 164: 1321–5 McCusker J, Kruszewski Z, Lacey B, et al. Monitoring clinical research: report of one hospital’s experience. Can Med Assoc J 2001; 164: 1321–5
39.
go back to reference Smith T, Moore EJH, Tunstall-Pedoe H. Review by a local medical research ethics committee of the conduct of approved research projects, by examination of patients’case notes, consent forms, and research records and by interview. BMJ 1997; 314: 1588–90PubMedCrossRef Smith T, Moore EJH, Tunstall-Pedoe H. Review by a local medical research ethics committee of the conduct of approved research projects, by examination of patients’case notes, consent forms, and research records and by interview. BMJ 1997; 314: 1588–90PubMedCrossRef
40.
go back to reference Pickworth E. Should local research ethics committees monitor research they have approved? J Med Ethics 2000; 26: 330–3PubMedCrossRef Pickworth E. Should local research ethics committees monitor research they have approved? J Med Ethics 2000; 26: 330–3PubMedCrossRef
41.
go back to reference Ashcroft R, Pfeffer N. Ethics behind closed doors: do research ethics committees need secrecy? BMJ 2001; 322: 1294–6PubMedCrossRef Ashcroft R, Pfeffer N. Ethics behind closed doors: do research ethics committees need secrecy? BMJ 2001; 322: 1294–6PubMedCrossRef
42.
go back to reference Hoffenberg R. A National Association LRECs? J R Coll Physicians Lond 1992; 26: 423–31 Hoffenberg R. A National Association LRECs? J R Coll Physicians Lond 1992; 26: 423–31
43.
go back to reference Foster C. Why do research ethics committees disagree with each other? J R Coll Physicians Lond 1995; 29: 315–8PubMed Foster C. Why do research ethics committees disagree with each other? J R Coll Physicians Lond 1995; 29: 315–8PubMed
45.
go back to reference Lee PN, Fry JS, Forey BA. Trends in lung cancer, chronic obstructive lung disease, and emphysema death rates for England and Wales 1941–85 and their relation to trends in cigarette smoking. Thorax 1990; 45: 657–65PubMedCrossRef Lee PN, Fry JS, Forey BA. Trends in lung cancer, chronic obstructive lung disease, and emphysema death rates for England and Wales 1941–85 and their relation to trends in cigarette smoking. Thorax 1990; 45: 657–65PubMedCrossRef
46.
go back to reference Harris TC. Re: OOH – near school and bulletins. BATES Numbers 511999051–9052, 1991. RJ Reynolds Tobacco Company Online Litigation Document Archive [online]. Available from URL: http://www.rjrtdocs.com [Accessed 2002 Jan 21] Harris TC. Re: OOH – near school and bulletins. BATES Numbers 511999051–9052, 1991. RJ Reynolds Tobacco Company Online Litigation Document Archive [online]. Available from URL: http://​www.​rjrtdocs.​com [Accessed 2002 Jan 21]
47.
go back to reference Phair JJ, Carey GCR, Shephard RJ. Measuring human reactions to air pollution. J Franklin Inst 1958; monograph 4: 37–51 Phair JJ, Carey GCR, Shephard RJ. Measuring human reactions to air pollution. J Franklin Inst 1958; monograph 4: 37–51
48.
go back to reference Carey GC, Harley WJ, Melvin WW, et al. A clinical study of a respiratory disease in Kingsport, Tennessee. Cincinnati (OH): Kettering Laboratory, 1957 Carey GC, Harley WJ, Melvin WW, et al. A clinical study of a respiratory disease in Kingsport, Tennessee. Cincinnati (OH): Kettering Laboratory, 1957
49.
go back to reference National Cancer Institute. Smoking and Tobacco Control Monograph 11: state and local legislative action to reduce tobacco use. Bethesda (MD): Department of Health and Human Services, National Institutes of Health, National Cancer Institute, 2000. Report No.: NIH Publication 00–4804 National Cancer Institute. Smoking and Tobacco Control Monograph 11: state and local legislative action to reduce tobacco use. Bethesda (MD): Department of Health and Human Services, National Institutes of Health, National Cancer Institute, 2000. Report No.: NIH Publication 00–4804
50.
go back to reference National Cancer Institute. Population based smoking cessation: proceedings of a conference on what works to influence cessation in the general population. Bethesda (MD): Department of Health and Human Services, National Institutes of Health, National Cancer Institute, 2000. Report No.: NIH Publication 00–4892, National Cancer Institute. Population based smoking cessation: proceedings of a conference on what works to influence cessation in the general population. Bethesda (MD): Department of Health and Human Services, National Institutes of Health, National Cancer Institute, 2000. Report No.: NIH Publication 00–4892,
51.
go back to reference de Gruchy J, Lewin S. Ethics that exclude: the role of ethics committees in lesbian and gay health research in SouthAfrica. Am J Public Health 2001; 91: 865–8PubMedCrossRef de Gruchy J, Lewin S. Ethics that exclude: the role of ethics committees in lesbian and gay health research in SouthAfrica. Am J Public Health 2001; 91: 865–8PubMedCrossRef
52.
go back to reference Soderstrom M. Why researchers excluded women from their trial populations. Lakartidningen 2001; 98: 1524–8PubMed Soderstrom M. Why researchers excluded women from their trial populations. Lakartidningen 2001; 98: 1524–8PubMed
53.
go back to reference Marrococco A, Stewart DE. We’ve come a long way, maybe: recruitment of women and analysis of results by sex in clinical research. J Womens Health 2001; 10: 175–9 Marrococco A, Stewart DE. We’ve come a long way, maybe: recruitment of women and analysis of results by sex in clinical research. J Womens Health 2001; 10: 175–9
54.
go back to reference Shephard RJ. Human rights and worker selection [editorial]. Can J Sport Sci 1989; 14: 132–3PubMed Shephard RJ. Human rights and worker selection [editorial]. Can J Sport Sci 1989; 14: 132–3PubMed
55.
go back to reference Shephard RJ, Bonneau J. Avoiding gender discrimination in recruitment standards for police officers. Can J Appl Physiol. In press Shephard RJ, Bonneau J. Avoiding gender discrimination in recruitment standards for police officers. Can J Appl Physiol. In press
56.
go back to reference Savulescu J, Chalmers I, Blunt J. Are ethics research committees behaving unethically?. Some suggestions for improving accountability. BMJ 1996; 313: 1390–3PubMedCrossRef Savulescu J, Chalmers I, Blunt J. Are ethics research committees behaving unethically?. Some suggestions for improving accountability. BMJ 1996; 313: 1390–3PubMedCrossRef
57.
go back to reference Kleinman I, Baylis F, Rodgers S, et al. Bioethics for clinicians: 8. Confidentiality. Can Med Assoc J 1997; 156: 521–4 Kleinman I, Baylis F, Rodgers S, et al. Bioethics for clinicians: 8. Confidentiality. Can Med Assoc J 1997; 156: 521–4
59.
go back to reference Doyal L. Informed consent inmedical research: journals should not publish research to which patients have not given fully informed consent -with three exceptions. BMJ 1997; 314: 1107–11PubMedCrossRef Doyal L. Informed consent inmedical research: journals should not publish research to which patients have not given fully informed consent -with three exceptions. BMJ 1997; 314: 1107–11PubMedCrossRef
60.
go back to reference Hébert PC, Hoffmaster B, Glass KC, et al. Bioethics for clinicians: 7. Truth telling. Can Med Assoc J 1997; 156: 225–8 Hébert PC, Hoffmaster B, Glass KC, et al. Bioethics for clinicians: 7. Truth telling. Can Med Assoc J 1997; 156: 225–8
61.
go back to reference Deaths in Bristol have changed the face of British medicine [news]. Can Med Assoc J 2001; 165: 628 Deaths in Bristol have changed the face of British medicine [news]. Can Med Assoc J 2001; 165: 628
62.
go back to reference Shephard RJ. Exercise and sudden death: an overview. Sport Sci Rev 1995; 4 (2): 1–13 Shephard RJ. Exercise and sudden death: an overview. Sport Sci Rev 1995; 4 (2): 1–13
65.
go back to reference Ruyter KW, Nyquist I. Children as medical research subjects. Tidsskr Nor Laegeforen 1999; 119: 2833–7PubMed Ruyter KW, Nyquist I. Children as medical research subjects. Tidsskr Nor Laegeforen 1999; 119: 2833–7PubMed
66.
go back to reference Harrison C, Kenny N, Sidarous M, et al. Bioethics for clinicians: 9. Involving children in medical decisions. Can Med Assoc J 1997; 156: 825–8 Harrison C, Kenny N, Sidarous M, et al. Bioethics for clinicians: 9. Involving children in medical decisions. Can Med Assoc J 1997; 156: 825–8
67.
go back to reference Coimbra CE, Santos RV. Ethics and biomedical research in Amerindian societies in Brazil. Cad Saude Publica 1996; 12: 417–22PubMed Coimbra CE, Santos RV. Ethics and biomedical research in Amerindian societies in Brazil. Cad Saude Publica 1996; 12: 417–22PubMed
68.
go back to reference Kaufert J, Commanda L, Elias B, et al. Evolving participation of aboriginal communities in health research ethics review: the impact of the Inuvik workshop. Int J Circumpolar Health 1999; 58: 134–44PubMed Kaufert J, Commanda L, Elias B, et al. Evolving participation of aboriginal communities in health research ethics review: the impact of the Inuvik workshop. Int J Circumpolar Health 1999; 58: 134–44PubMed
69.
go back to reference Macaulay AC, Delormier T, McComber AM, et al. Participatory research with native community of Kahnawake creates innovative Code of Research Ethics. Can J Public Health 1998; 89: 105–8PubMed Macaulay AC, Delormier T, McComber AM, et al. Participatory research with native community of Kahnawake creates innovative Code of Research Ethics. Can J Public Health 1998; 89: 105–8PubMed
70.
go back to reference Macaulay AC, Cross EJ, Delormier T, et al. Developing a Code of Research Ethics for research with a Native community in Canada; a report from the Kahnawake Schools Diabetes Prevention Project. Int J Circumpolar Health 1998; 57 Suppl. 1: 38–40PubMed Macaulay AC, Cross EJ, Delormier T, et al. Developing a Code of Research Ethics for research with a Native community in Canada; a report from the Kahnawake Schools Diabetes Prevention Project. Int J Circumpolar Health 1998; 57 Suppl. 1: 38–40PubMed
71.
go back to reference Karlawish JH, Hougham GW, Stocking CB, et al. What is the quality of the reporting of research ethics in publications of nursing home research? J Am Geriatr Soc 1999; 47: 76–81PubMed Karlawish JH, Hougham GW, Stocking CB, et al. What is the quality of the reporting of research ethics in publications of nursing home research? J Am Geriatr Soc 1999; 47: 76–81PubMed
72.
go back to reference Erlen JA, Sauder RJ,MellorsMP. Incentives in research: ethical issues. Orthop Nurs 1999; 18: 84–7PubMed Erlen JA, Sauder RJ,MellorsMP. Incentives in research: ethical issues. Orthop Nurs 1999; 18: 84–7PubMed
73.
go back to reference Guest S. Compensation for subjects of medical research: the moral rights of patients and the power of research ethics committees. J Med Ethics 1997; 23: 181–5PubMedCrossRef Guest S. Compensation for subjects of medical research: the moral rights of patients and the power of research ethics committees. J Med Ethics 1997; 23: 181–5PubMedCrossRef
74.
go back to reference Joseph KS. Ethics in clinical research: searching for absolutes. Can Med Assoc J 1998; 158: 1303–5 Joseph KS. Ethics in clinical research: searching for absolutes. Can Med Assoc J 1998; 158: 1303–5
75.
go back to reference Singer PA, Benetar SR. Beyond Helsinki: a vision for global health ethics. Improved ethical behaviour depends on strengthening capacity. BMJ 2001; 322: 747–8PubMedCrossRef Singer PA, Benetar SR. Beyond Helsinki: a vision for global health ethics. Improved ethical behaviour depends on strengthening capacity. BMJ 2001; 322: 747–8PubMedCrossRef
76.
77.
go back to reference Bouchard C, Shephard RJ, Stephens T. Physical activity, fitness and health. Champaign (IL): Human Kinetics Publishers, 1994 Bouchard C, Shephard RJ, Stephens T. Physical activity, fitness and health. Champaign (IL): Human Kinetics Publishers, 1994
78.
go back to reference Rechnitzer P, Sangal S, Cunningham D, et al. Acontrolled prospective study of the effect of endurance training on the recurrence rate of myocardial infarction. Am J Epidemiol 1975; 102: 358–65PubMed Rechnitzer P, Sangal S, Cunningham D, et al. Acontrolled prospective study of the effect of endurance training on the recurrence rate of myocardial infarction. Am J Epidemiol 1975; 102: 358–65PubMed
79.
go back to reference Shephard RJ, Rode A. The health consequences of ’modernization’. London: Cambridge University Press, 1996CrossRef Shephard RJ, Rode A. The health consequences of ’modernization’. London: Cambridge University Press, 1996CrossRef
80.
81.
go back to reference McKneally MF, Dickens BM, Meslin EM, et al. Bioethics for clinicians: 13. Resource allocation. Can Med Assoc J 1997; 157: 163–7 McKneally MF, Dickens BM, Meslin EM, et al. Bioethics for clinicians: 13. Resource allocation. Can Med Assoc J 1997; 157: 163–7
82.
go back to reference Williams JR. Ethics and human rights in South African medicine. Can Med Assoc J 2000; 162: 1167–70 Williams JR. Ethics and human rights in South African medicine. Can Med Assoc J 2000; 162: 1167–70
83.
84.
85.
go back to reference Wise P, Drury M. Pharmaceutical trials in general practice: the first 100 protocols. An audit by the clinical research ethics committee of the Royal College of General Practitioners. BMJ 1996; 313: 1245–8PubMedCrossRef Wise P, Drury M. Pharmaceutical trials in general practice: the first 100 protocols. An audit by the clinical research ethics committee of the Royal College of General Practitioners. BMJ 1996; 313: 1245–8PubMedCrossRef
86.
go back to reference Anonymous. Uniform requirements for manuscripts submitted to biomedical journals. International Committee of Medical Journal Editors. Med Educ 1999; 33: 66–78CrossRef Anonymous. Uniform requirements for manuscripts submitted to biomedical journals. International Committee of Medical Journal Editors. Med Educ 1999; 33: 66–78CrossRef
87.
go back to reference Amdur RJ, Biddle C. Institutional review board approval and publication of human research results. JAMA 1997; 277: 909–14PubMedCrossRef Amdur RJ, Biddle C. Institutional review board approval and publication of human research results. JAMA 1997; 277: 909–14PubMedCrossRef
90.
go back to reference Association of American Universities. Framework for institutional policies and procedures to deal with fraud in research. Washington, DC: Association of American Universities, 1988 Association of American Universities. Framework for institutional policies and procedures to deal with fraud in research. Washington, DC: Association of American Universities, 1988
91.
go back to reference Broad W, Wade N. Betrayers of Truth. New York (NY): Simon and Schuster, 1982 Broad W, Wade N. Betrayers of Truth. New York (NY): Simon and Schuster, 1982
92.
go back to reference Lock S. Misconduct in research: does it exist in Britain? BMJ 1988; 297: 531–5 Lock S. Misconduct in research: does it exist in Britain? BMJ 1988; 297: 531–5
93.
go back to reference Royal College of Physicians of London. Report of the working party on fraud and misconduct in medical research: causes, investigation and prevention. J R Coll Physicians Lond 1991; 25: 89–94 Royal College of Physicians of London. Report of the working party on fraud and misconduct in medical research: causes, investigation and prevention. J R Coll Physicians Lond 1991; 25: 89–94
94.
go back to reference Korenman SG, Berk R, Wenger NS, et al. Evaluation of the research norms of scientists and administrators responsible for academic research. JAMA 1998; 279: 41–7PubMedCrossRef Korenman SG, Berk R, Wenger NS, et al. Evaluation of the research norms of scientists and administrators responsible for academic research. JAMA 1998; 279: 41–7PubMedCrossRef
95.
go back to reference Evans I. Dealing with research misconduct in the United Kingdom. Conduct unbecoming: the MRC’s approach. BMJ 1998; 316: 1726–33CrossRef Evans I. Dealing with research misconduct in the United Kingdom. Conduct unbecoming: the MRC’s approach. BMJ 1998; 316: 1726–33CrossRef
96.
go back to reference Marco CA, Larkin GL. Research ethics: ethical issues of data reporting and the quest for authenticity. Acad Emerg Med 2000; 7: 691–4PubMedCrossRef Marco CA, Larkin GL. Research ethics: ethical issues of data reporting and the quest for authenticity. Acad Emerg Med 2000; 7: 691–4PubMedCrossRef
97.
go back to reference International Committee of Medical Editors. Statement on project-specific industry support for research. Can Med Assoc J 1998; 158: 615–6 International Committee of Medical Editors. Statement on project-specific industry support for research. Can Med Assoc J 1998; 158: 615–6
99.
go back to reference Lock S, Wells F. Fraud and misconduct in medical research. London: BMJ Publishing Group, 1996 Lock S, Wells F. Fraud and misconduct in medical research. London: BMJ Publishing Group, 1996
100.
go back to reference Chantler C. Dealing with research misconduct in the United Kingdom. Deception: difficulties and initiatives. BMJ 1998; 316: 1726–33CrossRef Chantler C. Dealing with research misconduct in the United Kingdom. Deception: difficulties and initiatives. BMJ 1998; 316: 1726–33CrossRef
101.
go back to reference Merton RK. A note on science and democracy. J Leg Polit Sociol 1942; 1: 115–26 Merton RK. A note on science and democracy. J Leg Polit Sociol 1942; 1: 115–26
102.
103.
go back to reference Rennie D. Dealing with research misconduct in the United Kingdom: an American perspective on research integrity. BMJ 1998; 316: 1726–33PubMedCrossRef Rennie D. Dealing with research misconduct in the United Kingdom: an American perspective on research integrity. BMJ 1998; 316: 1726–33PubMedCrossRef
104.
go back to reference Riis P. Dealing with research misconduct in the United Kingdom. BMJ 1998; 316: 1726–33CrossRef Riis P. Dealing with research misconduct in the United Kingdom. BMJ 1998; 316: 1726–33CrossRef
105.
106.
go back to reference Deeks J. Systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001; 323: 157–62PubMedCrossRef Deeks J. Systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001; 323: 157–62PubMedCrossRef
107.
go back to reference Stern JM. Publication bias: evidence of delayed publication in a cohort study of clinical projects. BMJ 1997; 315: 640–5PubMedCrossRef Stern JM. Publication bias: evidence of delayed publication in a cohort study of clinical projects. BMJ 1997; 315: 640–5PubMedCrossRef
108.
go back to reference Van Camp SP, Bloor CM, Mueller FO, et al. Non-traumatic sports deaths in high-school and college athletes. Med Sci Sports Exerc 1995; 27: 641–7PubMed Van Camp SP, Bloor CM, Mueller FO, et al. Non-traumatic sports deaths in high-school and college athletes. Med Sci Sports Exerc 1995; 27: 641–7PubMed
109.
go back to reference Maron BJ. Hypertrophic cardiomyopathy in athletes: catching a killer. Physician Sportsmed 1993; 21 (9): 83–91 Maron BJ. Hypertrophic cardiomyopathy in athletes: catching a killer. Physician Sportsmed 1993; 21 (9): 83–91
110.
go back to reference Sibbald B. All conflicts of interest are not created equal [letter]. Can Med Assoc J 1999; 160: 1866 Sibbald B. All conflicts of interest are not created equal [letter]. Can Med Assoc J 1999; 160: 1866
111.
go back to reference Phillips RA, Hoey J. Constraints of interest: lessons at the Hospital for Sick Children. Can Med Assoc J 1998; 159: 955–7 Phillips RA, Hoey J. Constraints of interest: lessons at the Hospital for Sick Children. Can Med Assoc J 1998; 159: 955–7
112.
go back to reference Shuchman M. Independent review adds to controversy at Sick Kids. Can Med Assoc J 1999; 160: 386–8 Shuchman M. Independent review adds to controversy at Sick Kids. Can Med Assoc J 1999; 160: 386–8
113.
go back to reference Lexchin J. Secrecy and the Health Protection Branch. Can Med Assoc J 1998; 159: 481–3 Lexchin J. Secrecy and the Health Protection Branch. Can Med Assoc J 1998; 159: 481–3
114.
go back to reference Silversides A. Private sector becoming the key to research funding in Canada. Can Med Assoc J 1998; 159: 397–8 Silversides A. Private sector becoming the key to research funding in Canada. Can Med Assoc J 1998; 159: 397–8
115.
go back to reference Hole OP, Winther FO, Straume B. Clinical research: the influence of the pharmaceutical industry. Eur J Clin Pharamacol 2001; 56: 851–3CrossRef Hole OP, Winther FO, Straume B. Clinical research: the influence of the pharmaceutical industry. Eur J Clin Pharamacol 2001; 56: 851–3CrossRef
116.
go back to reference Smith R. Why journals should not publish articles funded by the tobacco industry. BMJ 2000; 321: 1075–6 Smith R. Why journals should not publish articles funded by the tobacco industry. BMJ 2000; 321: 1075–6
117.
go back to reference King J. Why journals should not publish articles funded by the tobacco industry. BMJ 2000; 321: 1074–5PubMedCrossRef King J. Why journals should not publish articles funded by the tobacco industry. BMJ 2000; 321: 1074–5PubMedCrossRef
118.
go back to reference Lemmens T, Singer PA. Bioethics for clinicians: 17. Conflict of interest in research, education and patient care. Can Med Assoc J 1998; 159: 960–5 Lemmens T, Singer PA. Bioethics for clinicians: 17. Conflict of interest in research, education and patient care. Can Med Assoc J 1998; 159: 960–5
119.
120.
go back to reference NEJM’s new editor cut ties with 20 drug companies before taking helm. Can Med Assoc J 2000; 163: 1182 NEJM’s new editor cut ties with 20 drug companies before taking helm. Can Med Assoc J 2000; 163: 1182
121.
go back to reference Lynoe N. Medical ethics — an endeavour for social medicine? Scand J Soc Med 1997; 25: 225–8PubMed Lynoe N. Medical ethics — an endeavour for social medicine? Scand J Soc Med 1997; 25: 225–8PubMed
122.
123.
go back to reference Teaching medical ethics. BMJ 2000; 316: 1623 Teaching medical ethics. BMJ 2000; 316: 1623
Metadata
Title
Ethics in Exercise Science Research
Author
Roy J. Shephard
Publication date
01-03-2002
Publisher
Springer International Publishing
Published in
Sports Medicine / Issue 3/2002
Print ISSN: 0112-1642
Electronic ISSN: 1179-2035
DOI
https://doi.org/10.2165/00007256-200232030-00002