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Published in:

01-09-2006 | Leading Article

The Role of Topical Immune Response Modifiers in Skin Cancer

Authors: Courtney Woodmansee, Jessica Pillow, Dr Robert B. Skinner Jr

Published in: Drugs | Issue 13/2006

Abstract

Topical immune response modifiers include imiquimod and resiquimod. The mechanism of action of immune response modifiers is complex and not completely understood. It involves the stimulation of innate and cell-mediated immune responses through Toll-like receptor-mediated induction of cytokines. Imiquimod is approved for the treatment of actinic keratoses, superficial basal cell carcinomas and warts; it has also been documented to successfully treat other forms of skin cancer such as squamous cell carcinoma in situ, melanoma and extramammary Paget’s disease.

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Title: The Role of Topical Immune Response Modifiers in Skin Cancer
Authors: Courtney Woodmansee
Jessica Pillow
Dr Robert B. Skinner Jr
Publication date: 01-09-2006
Publisher: Springer International Publishing
Published in: Drugs / Issue 13/2006
Print ISSN: 0012-6667
Electronic ISSN: 1179-1950
DOI: https://doi.org/10.2165/00003495-200666130-00001

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