Published in:
01-11-2009 | Review Article
The Role of the Laboratory in the Diagnosis of Invasive Candidiasis
Authors:
Dr Maria Teresa Montagna, Giuseppina Caggiano, Elisa Borghi, Giulia Morace
Published in:
Drugs
|
Special Issue 1/2009
Login to get access
Abstract
A diagnosis of invasive candidiasis can be achieved using conventional approaches (microscopy, culture, serology), as well as new methods, including antigen detection and polymerase chain reaction (PCR) assays. Most of the conventional approaches lack sensitivity, especially for obtaining a diagnosis of invasive candidiasis in immunocompromised patients. Antigen detection and PCR assays represent a valid alternative, in terms of their high potential sensitivity and specificity, but these procedures still need to be standardized and evaluated in a large number of patients.