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01-11-2002 | Therapy In Practice

Management of Postoperative Nausea and Vomiting in Children

Authors: Pasquale De Negri, Dr Giorgio Ivani

Published in: Pediatric Drugs | Issue 11/2002

Abstract

In spite of improvements in anesthesia techniques, the ‘big little problem’ of postoperative nausea and vomiting (PONV) still exists. PONV can prolong recovery room stay and hospitalization, and is one of the most common causes of hospital readmission after day surgery.

While there is little evidence to support prophylactic administration of antiemetics in patients at low risk of PONV, the higher risk population could benefit from the use of adequate antiemetic drugs. A wide variety of pharmacological approaches have been reported to be effective, as well as some nonpharmacological approaches. Antiemetic drugs available to treat or prevent PONV include phenothiazines, antihistamines, anticholinergics, benzamides, butyrophenones and 5-HT₃ antagonists. Since available drugs still present undesired adverse effects and are not completely able to control PONV, clinical investigations are ongoing for more effective and better tolerated agents; indeed, the ideal antiemetic drug might be cost-effective for routine use.

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Title: Management of Postoperative Nausea and Vomiting in Children
Authors: Pasquale De Negri
Dr Giorgio Ivani
Publication date: 01-11-2002
Publisher: Springer International Publishing
Published in: Pediatric Drugs / Issue 11/2002
Print ISSN: 1174-5878
Electronic ISSN: 1179-2019
DOI: https://doi.org/10.2165/00128072-200204110-00003

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Management of Postoperative Nausea and Vomiting in Children

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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