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Published in: Annals of Surgical Oncology 3/2021

01-03-2021 | Metastasis | Hepatobiliary Tumors

Bilobar Colorectal Liver Metastases: Challenges and Opportunities

Authors: Matthew E. B. Dixon, MD, FACS, Niraj J. Gusani, MD, MS, FACS

Published in: Annals of Surgical Oncology | Issue 3/2021

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Excerpt

The boundaries of possibility in hepatic surgery continue to expand. Refinements in surgical and anesthetic techniques, deeper understanding of hepatic anatomy, development of new technologies and strategies for hepatic transection, and improvements in postoperative care all have contributed to making hepatic surgery safer while also broadening the universe of patients who might benefit from this therapy. As surgeons versed in the principles of modern hepatic surgery through dedicated training programs at high-volume centers become more widely disseminated, surgical options can be offered to more and more patients who need them. Patients with colorectal liver metastases (CRLM) represent an important group who stand to gain from these advancements. …
Literature
1.
go back to reference Beppu T, Miyamoto Y, Sakamoto Y, et al. Chemotherapy and targeted therapy for patients with initially unresectable colorectal liver metastases, focusing on conversion hepatectomy and long-term survival. Ann Surg Oncol. 2014;21(Suppl 3):405–13.CrossRef Beppu T, Miyamoto Y, Sakamoto Y, et al. Chemotherapy and targeted therapy for patients with initially unresectable colorectal liver metastases, focusing on conversion hepatectomy and long-term survival. Ann Surg Oncol. 2014;21(Suppl 3):405–13.CrossRef
2.
go back to reference Pulitano C, Bodingbauer M, Aldrighetti L, et al. Liver resection for colorectal metastases in presence of extrahepatic disease: results from an international multi-institutional analysis. Ann Surg Oncol. 2011;18:1380–8.CrossRef Pulitano C, Bodingbauer M, Aldrighetti L, et al. Liver resection for colorectal metastases in presence of extrahepatic disease: results from an international multi-institutional analysis. Ann Surg Oncol. 2011;18:1380–8.CrossRef
3.
go back to reference Mise Y, Aloia TA, Brudvik KW, et al. Parenchymal-sparing hepatectomy in colorectal liver metastasis improves salvageability and survival. Ann Surg. 2016;263:146–52.CrossRef Mise Y, Aloia TA, Brudvik KW, et al. Parenchymal-sparing hepatectomy in colorectal liver metastasis improves salvageability and survival. Ann Surg. 2016;263:146–52.CrossRef
4.
go back to reference Broquet A, Abdalla E, Kopetz S, et al. High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome. J Clin Oncol. 2011;29:1083–90.CrossRef Broquet A, Abdalla E, Kopetz S, et al. High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome. J Clin Oncol. 2011;29:1083–90.CrossRef
6.
go back to reference Jaeck D, Oussoultzoglou E, Rosso E, et al. A two-stage hepatectomy procedure combined with portal vein embolization to achieve curative resetion for initially unresectable multiple and biolobar colorectal liver metastases. Ann Surg. 2004;240:1037–49.CrossRef Jaeck D, Oussoultzoglou E, Rosso E, et al. A two-stage hepatectomy procedure combined with portal vein embolization to achieve curative resetion for initially unresectable multiple and biolobar colorectal liver metastases. Ann Surg. 2004;240:1037–49.CrossRef
7.
go back to reference Elias D, De Baere T, Roche A, et al. During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma. Br J Surg. 1999;86:784–8.CrossRef Elias D, De Baere T, Roche A, et al. During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma. Br J Surg. 1999;86:784–8.CrossRef
8.
go back to reference Cloyd J, Aloia TA. Hammer versus Swiss Army Knife: developing a strategy for the management of bilobar colorectal liver metastases. Surgery. 2017;162:12–7.CrossRef Cloyd J, Aloia TA. Hammer versus Swiss Army Knife: developing a strategy for the management of bilobar colorectal liver metastases. Surgery. 2017;162:12–7.CrossRef
10.
go back to reference Wicherts DA, Miller R, de Haas RJ, et al. Long-term results of two-stage hepatetomy for irresectable colorectal cancer liver metastases. Ann Surg. 2008;248:994–1005.CrossRef Wicherts DA, Miller R, de Haas RJ, et al. Long-term results of two-stage hepatetomy for irresectable colorectal cancer liver metastases. Ann Surg. 2008;248:994–1005.CrossRef
11.
go back to reference Picardo A, Karpoff HM, Ng B, Lee J, Brennan MF, Fong Y. Partial hepatecctomy accelerates local tumor growth: potential roles of local cytokine activation. Surgery. 1998;124:57–64.CrossRef Picardo A, Karpoff HM, Ng B, Lee J, Brennan MF, Fong Y. Partial hepatecctomy accelerates local tumor growth: potential roles of local cytokine activation. Surgery. 1998;124:57–64.CrossRef
12.
go back to reference Kokudo N, Tada K, Seki M, et al. Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization. Hepatology. 2001;34:267–72.CrossRef Kokudo N, Tada K, Seki M, et al. Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization. Hepatology. 2001;34:267–72.CrossRef
14.
go back to reference Laurent C, Fernandez B, Marichez A, et al. Radiological simultaneous portohepatic vein embolization (RASPE) before major hepatectomy: a better way to optimize liver hypertrophy compared to portal vein embolization. Ann Surg. 2020;272:199–205.CrossRef Laurent C, Fernandez B, Marichez A, et al. Radiological simultaneous portohepatic vein embolization (RASPE) before major hepatectomy: a better way to optimize liver hypertrophy compared to portal vein embolization. Ann Surg. 2020;272:199–205.CrossRef
15.
go back to reference Sandstrom P, Rosok BI, Sparrelid E, et al. ALPPS improves resectability compared with conventional two-stage hepatectomy in patients with advanced colorectal liver metastasis: results from a Scandinavian multicenter randomized controlled trial (LIGRO trial). Ann Surg. 2018;267:833–40.CrossRef Sandstrom P, Rosok BI, Sparrelid E, et al. ALPPS improves resectability compared with conventional two-stage hepatectomy in patients with advanced colorectal liver metastasis: results from a Scandinavian multicenter randomized controlled trial (LIGRO trial). Ann Surg. 2018;267:833–40.CrossRef
16.
go back to reference Krell RW, Reames BN, Hendren S, et al. Surgical referral for colorectal lilver metastses: a population-based survey. Ann Surg Oncol. 2015;22:2179–94.CrossRef Krell RW, Reames BN, Hendren S, et al. Surgical referral for colorectal lilver metastses: a population-based survey. Ann Surg Oncol. 2015;22:2179–94.CrossRef
Metadata
Title
Bilobar Colorectal Liver Metastases: Challenges and Opportunities
Authors
Matthew E. B. Dixon, MD, FACS
Niraj J. Gusani, MD, MS, FACS
Publication date
01-03-2021
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 3/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-09468-5

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