Published in:
01-12-2020 | ASO Author Reflections
ASO Author Reflections: Is Perioperative Steroids Administration Beneficial for Patients Undergoing Major Hepatectomy with Extrahepatic Bile Duct Resection?
Authors:
Shunsuke Onoe, MD, Yukihiro Yokoyama, MD, Tomoki Ebata, MD, Masato Nagino, MD
Published in:
Annals of Surgical Oncology
|
Special Issue 3/2020
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Excerpt
Major hepatectomy still involves a long operation and considerable blood loss, which is associated with a potential risk for postoperative adverse events such as liver failure.
1 It has been reported that perioperative use of steroids may reduce adverse events.
2 To date, five randomized controlled trials (RCT) have assessed the clinical benefit of perioperative steroid administration in hepatectomy.
3 However, all of these trials involved a substantial number of ‘‘minor’’ hepatectomies, such as a partial hepatectomy or segmental hepatectomy. The benefit of steroid administration for patients undergoing “complex” hepatectomy such as major hepatectomy (resection of more than three segments) with extrahepatic bile duct resection is still unclear. …
