Published in:
01-10-2020 | Metastasis | ASO Author Reflections
ASO Author Reflections: A Nomogram to Predict Recurrence after Curative-Intent Resection for Neuroendocrine Liver Metastasis
Authors:
Diamantis I. Tsilimigras, MD, Jun-Xi Xiang, MD, Xu-Feng Zhang, MD, PhD, Timothy M. Pawlik, MD, MPH, PhD
Published in:
Annals of Surgical Oncology
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Issue 10/2020
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Excerpt
The European Neuroendocrine Tumor Society (ENETS) guidelines recommend resection of neuroendocrine liver metastasis (NELM) when NELM originate from well- or moderately differentiated primary tumors and when at least 90% of the tumor burden can be safely removed.
1 Although surgical resection is the mainstay of treatment for patients with resectable NELM, up to 70–80% of patients with NELM will relapse or experience disease progression following liver resection.
2‐
4 Therefore, there is a need for better risk stratification and accurate prediction of recurrence among patients who undergo curative-intent resection for NELM. By utilizing a large international, multi-institutional cohort, we sought to develop and validate a nomogram to estimate patient prognosis after liver resection for NELM.
5 …
