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01-06-2020 | Breast Cancer | ASO Author Reflections

ASO Author Reflections: SLNB with RT May Be Sufficient in Occult Breast Cancer after NAC

Authors: Brianna L. Cohen, MD, Francis I. Macedo, MD

Published in: Annals of Surgical Oncology | Issue 6/2020

Excerpt

Significant efforts have been made to identify cohorts of women with involved sentinel lymph nodes (SLNs) with low risk of non-SLN involvement in an attempt to avoid unnecessary axillary lymphadenectomy (ALND). The ACOSOGZ0011 represented a milestone in the management of early breast cancer (cT1–2) with limited lymph node (LN) involvement (1–2 LNs+).1 In this study, no survival [local recurrence, disease-free survival, and overall survival (OS)] difference was found between patients undergoing sentinel lymph node biopsy (SLNB) and those undergoing ALND.1 …

Giuliano AE, McCall L, Beitch P, et al. Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial. Ann Surg 2010; 252:426–32.PubMedPubMedCentral

National Comprehensive Cancer Network (NCCN). Clinical practice guidelines oncology—breast cancer (Version 2.2019). 2019; https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf. Accessed 2 July 2019.

Khandelwal AK Garguilo GA. Therapeutic options for occult breast cancer: a survey of the American Society of Breast Surgeons and review of the literature. Am J Surg 2005; 190:609–13.CrossRef

Cohen BL, Collier AL, Kelly N, et al. Surgical management of the axilla in patients with occult breast cancer (cT0 N+) after neoadjuvant chemotherapy. Ann Surg Oncol. (2020). https://link.springer.com/article/10.1245/s10434-020-08227-w. CrossRef

Moo TA, Jochelson MS, Zabor EC, et al. Is clinical exam of the axilla sufficient to select node-positive patients who downstage after NAC for SLNB? A comparison of the accuracy of clinical exam versus MRI. Ann Surg Oncol. 2019;26(13):4238–43.CrossRef

Title: ASO Author Reflections: SLNB with RT May Be Sufficient in Occult Breast Cancer after NAC
Authors: Brianna L. Cohen, MD
Francis I. Macedo, MD
Publication date: 01-06-2020
Publisher: Springer International Publishing
Keywords: Breast Cancer
Breast Cancer
Published in: Annals of Surgical Oncology / Issue 6/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-020-08345-5

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ASO Author Reflections: SLNB with RT May Be Sufficient in Occult Breast Cancer after NAC

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