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Annals of Surgical Oncology

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01-08-2020 | Cystectomy | Colorectal Cancer

De Novo Secondary Adenocarcinoma in the Colon Used as Urinary Diversion Not in Contact with the Fecal Stream: Systematic Review and Meta-analysis

Authors: Antonio V. Sterpetti, MD, Umberto Costi, MD, Raffaele Grande, MD, Giuseppe D’Ermo, MD, Paolo Sapienza, MD

Published in: Annals of Surgical Oncology | Issue 8/2020

Abstract

Background

A systematic review with a meta-analysis was performed to determine the prevalence and risk factors for secondary de novo adenocarcinoma in the colon used as a urinary diversion not exposed to the fecal stream.

Methods

The systematic review of the literature identified 47 patients with secondary adenocarcinoma in a colonic urinary diversion not exposed to the fecal stream.

Results

The diagnosis of secondary adenocarcinoma was determined due to the presence major local symptoms and because the cancer in half of the patients was detected at an advanced stage. Diagnosis at an earlier stage was associated with long-term cancer-free survival.

Conclusions

The authors concluded that cystoscopy-colonoscopy screening as suggested by the American Gastroenterology Society for the general population should be applied to patients who have colon urinary diversion not exposed to the fecal stream. For patients with active high-grade inflammation, difficulty with self-catheterization, or symptoms, cystoscopy should be performed earlier. Resection of the tumor at an early stage offers better clinical outcomes with longer survival rates.

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Title: De Novo Secondary Adenocarcinoma in the Colon Used as Urinary Diversion Not in Contact with the Fecal Stream: Systematic Review and Meta-analysis
Authors: Antonio V. Sterpetti, MD
Umberto Costi, MD
Raffaele Grande, MD
Giuseppe D’Ermo, MD
Paolo Sapienza, MD
Publication date: 01-08-2020
Publisher: Springer International Publishing
Keyword: Cystectomy
Published in: Annals of Surgical Oncology / Issue 8/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-020-08300-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

De Novo Secondary Adenocarcinoma in the Colon Used as Urinary Diversion Not in Contact with the Fecal Stream: Systematic Review and Meta-analysis

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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