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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2019

01-12-2019 | Gastric Cancer | ASO Author Reflections

ASO Author Reflections: Current Status of Treatment of Peritoneal Carcinomatosis from Gastric Cancer Origin in Spain: Is It Possible to Cure These Patients?

Authors: Israel Manzanedo, MD, Fernando Pereira, MD, PhD

Published in: Annals of Surgical Oncology | Special Issue 3/2019

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Excerpt

Peritoneal carcinomatosis from gastric cancer origin has been considered a terminal stage of the disease, with poor prognosis. Nowadays, treatment with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for these patients is under discussion, but the few studies published show promising results.1,2 Despite this, the oncologic results of CRS and HIPEC in gastric cancer have not been as spectacular as in other indications, with substantial morbidity, so that few oncologic groups indicate CRS and HIPEC in gastric cancer. We wanted to know the real state of Spanish patients and, in particular, identify the subgroup of patients who can obtain the best results.3 …
Literature
1.
Glehen O, Gilly FN, Arvieux C, et al. Peritoneal carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. Ann Surg Oncol. 2010; 17:2370–7.CrossRef
2.
Yang XJ, Huang CQ, Suo T, et al. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial. Ann Surg Oncol. 2011; 18:1575–81.CrossRef
3.
Manzanedo I, Pereira F, Rihuete-Caro C. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for gastric cancer with peritoneal carcinomatosis: Multicenter study of Spanish Group of Peritoneal Oncologic Surgery (GECOP). Ann Surg Oncol. 2019; 26:2615–21.CrossRef
4.
Rihuete Caro C, Manzanedo I, Pereira F, Carrión-Álvarez L, Serrano A, Pérez-Viejo E. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with gastric cancer and peritoneal carcinomatosis. Eur J Surg Oncol. 2018; 44(11):1805–10.CrossRef
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Desiderio J, Chao J, Melstrom L, et al. The 30-year experience-A meta-analysis of randomised and high-quality non-randomised studies of hyperthermic intraperitoneal chemotherapy in the treatment of gastric cancer. Eur J Cancer. 2017; 79:1–14.CrossRef
Metadata
Title
ASO Author Reflections: Current Status of Treatment of Peritoneal Carcinomatosis from Gastric Cancer Origin in Spain: Is It Possible to Cure These Patients?
Authors
Israel Manzanedo, MD
Fernando Pereira, MD, PhD
Publication date
01-12-2019
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2019
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07952-1

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