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Published in: Annals of Surgical Oncology 2/2020

01-02-2020 | Colorectal Cancer

Extended Radical Resection: The Standard of Care for Patients with Advanced Pelvic Malignancy

Authors: Michael J. Solomon, MBBCH(Hons), BAO, MSc, DMed, DMedSc, FRCSI, FRACS, FASCRS, Kilian G. M. Brown, MBBS, BBiomed, M.Phil

Published in: Annals of Surgical Oncology | Issue 2/2020

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Excerpt

In 2019, extended radical resection (or exenterative surgery) represents the standard of care for patients with locally advanced and recurrent malignancies of the pelvis. Although acceptance of these ultra-radical procedures has been slow among surgeons due to the historically high rates of morbidity and mortality reported during the pioneering periods of the 1940s and 1950s, recent decades have seen dramatic improvements in outcomes, particularly for recurrent rectal cancer. These outcomes are now comparable with those of hepatic and pulmonary metastatectomy for primary colorectal cancer. In addition to robust morbidity and long-term survival data, quality-of-life improvements after surgery have now been confirmed by prospective studies.1
Literature
1.
go back to reference Steffens D, Solomon MJ, Young JM, et al. Cohort study of long-term survival and quality of life following pelvic exenteration. BJS Open. 2018;2:328–35.CrossRef Steffens D, Solomon MJ, Young JM, et al. Cohort study of long-term survival and quality of life following pelvic exenteration. BJS Open. 2018;2:328–35.CrossRef
3.
go back to reference PelvEx Collaborative. Changing outcomes following pelvic exenteration for locally advanced and recurrent rectal cancer. BJS Open. 2019;3:516–20.CrossRef PelvEx Collaborative. Changing outcomes following pelvic exenteration for locally advanced and recurrent rectal cancer. BJS Open. 2019;3:516–20.CrossRef
4.
go back to reference Beyond TME Collaboration. Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes. Br J Surg. 2013;100:1009–14.CrossRef Beyond TME Collaboration. Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes. Br J Surg. 2013;100:1009–14.CrossRef
5.
go back to reference Vallance AE, Harji D, Fearnhead NS, et al. Making an IMPACT: a priority setting consultation exercise to improve outcomes in patients with locally advanced, recurrent, and metastatic colorectal cancer. Eur J Surg Oncol. 2019;45(9):1567–74.CrossRef Vallance AE, Harji D, Fearnhead NS, et al. Making an IMPACT: a priority setting consultation exercise to improve outcomes in patients with locally advanced, recurrent, and metastatic colorectal cancer. Eur J Surg Oncol. 2019;45(9):1567–74.CrossRef
6.
go back to reference Venchiarutti RL, Solomon MJ, Koh CE, Young JM, Steffens D. Pushing the boundaries of pelvic exenteration by maintaining survival at the cost of morbidity. Br J Surg. 2019;106:1393–403.CrossRef Venchiarutti RL, Solomon MJ, Koh CE, Young JM, Steffens D. Pushing the boundaries of pelvic exenteration by maintaining survival at the cost of morbidity. Br J Surg. 2019;106:1393–403.CrossRef
7.
go back to reference Denost Q, Faucheron JL, Lefevre JH, et al. French current management and oncological results of locally recurrent rectal cancer. Eur J Surg Oncol. 2015;41:1645–52.CrossRef Denost Q, Faucheron JL, Lefevre JH, et al. French current management and oncological results of locally recurrent rectal cancer. Eur J Surg Oncol. 2015;41:1645–52.CrossRef
8.
go back to reference Harji DP, Griffiths B, McArthur DR, Sagar PM. Current UK management of locally recurrent rectal cancer. Colorectal Dis. 2012;14:1479–82.CrossRef Harji DP, Griffiths B, McArthur DR, Sagar PM. Current UK management of locally recurrent rectal cancer. Colorectal Dis. 2012;14:1479–82.CrossRef
9.
go back to reference Humphries EL, Kroon HM, Dudi-Venkata NN, Thomas ML, Moore JW, Sammour T. Short- and long-term outcomes of selective pelvic exenteration surgery in a low-volume specialized tertiary setting. ANZ J Surg. 2019;89:E226–E230.CrossRef Humphries EL, Kroon HM, Dudi-Venkata NN, Thomas ML, Moore JW, Sammour T. Short- and long-term outcomes of selective pelvic exenteration surgery in a low-volume specialized tertiary setting. ANZ J Surg. 2019;89:E226–E230.CrossRef
Metadata
Title
Extended Radical Resection: The Standard of Care for Patients with Advanced Pelvic Malignancy
Authors
Michael J. Solomon, MBBCH(Hons), BAO, MSc, DMed, DMedSc, FRCSI, FRACS, FASCRS
Kilian G. M. Brown, MBBS, BBiomed, M.Phil
Publication date
01-02-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 2/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07817-7

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