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Published in: Annals of Surgical Oncology 8/2019

01-08-2019 | Health Services Research and Global Oncology

Changing Trends in Industry Funding for Surgical Oncologists

Authors: Juan A. Santamaria-Barria, MD, Stacey Stern, MS, Adam Khader, MD, Mary Garland-Kledzik, MD, Anthony J. Scholer, MD, Trevan Fischer, MD, FACS, Anton Bilchik, MD, PhD, MBA, FACS

Published in: Annals of Surgical Oncology | Issue 8/2019

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Abstract

Background

With reductions in public funding, alternate research funding is essential to surgical oncologists (SOs). We aimed to examine current trends in industry funding of SOs.

Methods

Society of Surgical Oncology surgeons were identified and matched with board certification and years in practice. Departmental and hospital data were evaluated, and industry payments from 2013 to 2017 were matched with the Open Payment Data.

Results

Of the 1670 SOs identified, 922 (55%) had academic positions: 588 (64%) males and 334 (36%) females. Between 2013 and 2017, research payments totaling $46,596,706 were made to 162 SOs (17.5%): $40,774,716 (87%) for research related to drugs and clinical trials, compared with $5,194,199 (11%) for surgical devices (p = 0.018). Funding correlated with academic leadership and years in practice (p = 0.0001 and p = 0.0037). Massachusetts ($9,060,976), Texas ($7,656,228), and New York ($4,210,864) received the most funding, whereas Utah ($1,533,166/SO), Massachusetts ($1,294,425/SO), and Oregon ($1,241,702/SO) received the highest average payments per SO. The majority of funding was from Novartis ($16,045,608), Amgen ($6,810,832), and Merck ($3,758,299), for an oncolytic vaccine (talimogene laherparepvec, $5,939,007), a BRAF inhibitor (dabrafenib, $5,727,309), and a KIT inhibitor (imatinib, $4,323,586). Male SOs received funding more frequently than females (120/588 [20%] vs. 42/334 [12.6%]; p = 0.0027). Males also received more general payments (travel/lodging, food/beverage, consulting/speaker fees): $48,830 vs. $11,867 per male and female, respectively (p = 0.0001).

Conclusions

The majority of industry research payments to SOs are related to novel pharmaceuticals, which highlights the expanding influence SOs play in systemic therapies. Industry payments are influenced by location, gender, and academic leadership.
Appendix
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Literature
2.
go back to reference Keswani SG, Moles CM, Morowitz M, et al. The future of basic science in academic surgery: identifying barriers to success for surgeon-scientists. Ann. Surg. 2017;265(6):1053–1059.CrossRefPubMedPubMedCentral Keswani SG, Moles CM, Morowitz M, et al. The future of basic science in academic surgery: identifying barriers to success for surgeon-scientists. Ann. Surg. 2017;265(6):1053–1059.CrossRefPubMedPubMedCentral
3.
go back to reference Kibbe MR, Velazquez OC. The extinction of the surgeon scientist. Ann. Surg. 2017;265(6):1060–1061.CrossRefPubMed Kibbe MR, Velazquez OC. The extinction of the surgeon scientist. Ann. Surg. 2017;265(6):1060–1061.CrossRefPubMed
5.
go back to reference Galkina Cleary E, Beierlein JM, Khanuja NS, McNamee LM, Ledley FD. Contribution of NIH funding to new drug approvals 2010–2016. Proc. Natl. Acad. Sci. USA. 2018;115(10):2329–2334.CrossRefPubMedPubMedCentral Galkina Cleary E, Beierlein JM, Khanuja NS, McNamee LM, Ledley FD. Contribution of NIH funding to new drug approvals 2010–2016. Proc. Natl. Acad. Sci. USA. 2018;115(10):2329–2334.CrossRefPubMedPubMedCentral
6.
go back to reference Ehrhardt S, Appel LJ, Meinert CL. Trends in National Institutes of Health Funding for Clinical Trials Registered in ClinicalTrials.gov. JAMA. 2015;314(23):2566–2567.CrossRefPubMedPubMedCentral Ehrhardt S, Appel LJ, Meinert CL. Trends in National Institutes of Health Funding for Clinical Trials Registered in ClinicalTrials.gov. JAMA. 2015;314(23):2566–2567.CrossRefPubMedPubMedCentral
7.
go back to reference Chopra SS. MSJAMA: Industry funding of clinical trials: benefit or bias? JAMA. 2003;290(1):113–114.CrossRefPubMed Chopra SS. MSJAMA: Industry funding of clinical trials: benefit or bias? JAMA. 2003;290(1):113–114.CrossRefPubMed
12.
go back to reference Narahari AK, Mehaffey JH, Hawkins RB, et al. Surgeon scientists are disproportionately affected by declining NIH funding rates. J. Am. Coll. Surg. 2018;226(4):474–481.CrossRefPubMedPubMedCentral Narahari AK, Mehaffey JH, Hawkins RB, et al. Surgeon scientists are disproportionately affected by declining NIH funding rates. J. Am. Coll. Surg. 2018;226(4):474–481.CrossRefPubMedPubMedCentral
13.
go back to reference Wayant C, Turner E, Meyer C, Sinnett P, Vassar M. Financial conflicts of interest among oncologist authors of reports of clinical drug trials. JAMA Oncol. 2018;4(10):1426–1428.CrossRefPubMedPubMedCentral Wayant C, Turner E, Meyer C, Sinnett P, Vassar M. Financial conflicts of interest among oncologist authors of reports of clinical drug trials. JAMA Oncol. 2018;4(10):1426–1428.CrossRefPubMedPubMedCentral
14.
go back to reference Olavarria OA, Holihan JL, Cherla D, et al. Comparison of conflicts of interest among published hernia researchers self-reported with the centers for medicare and medicaid services open payments database. J. Am. Coll. Surg. 2017;224(5):800–804.CrossRefPubMed Olavarria OA, Holihan JL, Cherla D, et al. Comparison of conflicts of interest among published hernia researchers self-reported with the centers for medicare and medicaid services open payments database. J. Am. Coll. Surg. 2017;224(5):800–804.CrossRefPubMed
15.
go back to reference Nguyen V, Marmor RA, Ramamoorthy SL, Blair SL, Clary BM, Sicklick JK. Academic surgical oncologists’ productivity correlates with gender, grant funding, and institutional NCI comprehensive cancer center affiliation. Ann. Surg. Oncol. 2018;25(7):1852–1859.CrossRefPubMedPubMedCentral Nguyen V, Marmor RA, Ramamoorthy SL, Blair SL, Clary BM, Sicklick JK. Academic surgical oncologists’ productivity correlates with gender, grant funding, and institutional NCI comprehensive cancer center affiliation. Ann. Surg. Oncol. 2018;25(7):1852–1859.CrossRefPubMedPubMedCentral
17.
go back to reference Patel SV, Yu D, Elsolh B, Goldacre BM, Nash GM. Assessment of conflicts of interest in robotic surgical studies: validating author’s declarations with the open payments database. Ann. Surg. 2018;268(1):86–92.CrossRefPubMedPubMedCentral Patel SV, Yu D, Elsolh B, Goldacre BM, Nash GM. Assessment of conflicts of interest in robotic surgical studies: validating author’s declarations with the open payments database. Ann. Surg. 2018;268(1):86–92.CrossRefPubMedPubMedCentral
18.
go back to reference Ziai K, Pigazzi A, Smith BR, et al. Association of compensation from the surgical and medical device industry to physicians and self-declared conflict of interest. JAMA Surg. 2018;153(11):997–1002.CrossRefPubMedPubMedCentral Ziai K, Pigazzi A, Smith BR, et al. Association of compensation from the surgical and medical device industry to physicians and self-declared conflict of interest. JAMA Surg. 2018;153(11):997–1002.CrossRefPubMedPubMedCentral
Metadata
Title
Changing Trends in Industry Funding for Surgical Oncologists
Authors
Juan A. Santamaria-Barria, MD
Stacey Stern, MS
Adam Khader, MD
Mary Garland-Kledzik, MD
Anthony J. Scholer, MD
Trevan Fischer, MD, FACS
Anton Bilchik, MD, PhD, MBA, FACS
Publication date
01-08-2019
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 8/2019
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07380-1

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