ASO Author Reflections: Recurrence Predictors in Mucinous Appendiceal Tumors

Excerpt

Peritoneal dissemination from mucinous appendiceal tumors has long been vaguely described as pseudomyxoma peritonei (PMP); however, PMP is not an homogeneous entity. There is a wide variance in outcomes after surgical treatment of PMP,1 and some clinical reports of PMP have included primary mucinous tumors of the stomach, colon, pancreas, ovary, and urachus. Various attempts at histologic definitions and classification of mucinous appendiceal tumors with peritoneal dissemination have resulted in a confusing array of histologic terminology and acronyms (mucocele, mucinous cystadenoma, mucinous adenocarcinoma, LAMN, MTUMP, DPAM, PMCA, PMCA-I, etc.).2 There is now an emerging standardization with the Peritoneal Surface Oncology Group International (PSOGI) 2016 consensus statement,3 which adopted and further classified the 2010 WHO classification of this disease.4 We sought to investigate outcomes at our institution using this classification schema after uniform surgical treatment with complete cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). …