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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2018

01-12-2018 | ASO Author Reflections

ASO Author Reflections: Outcomes of Appendiceal Goblet Cell Carcinoid Tumors

Authors: Erica S. Tsang, MD, Hagen F. Kennecke, MD, MHA, FRCPC

Published in: Annals of Surgical Oncology | Special Issue 3/2018

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Excerpt

Goblet cell carcinoid (GCC) tumors of the appendix are rare mucinous neoplasms staged according to the system for adenocarcinomas (AJCC, 8th edition) with limited data surrounding optimal treatment regimens.1 The usual prognostic tools of TNM stage or Ki-67 have not proven as useful in the setting of appendiceal GCC. However, the histologic classification system first introduced by Tang et al.2 has correlated with survival outcomes, dividing cases into group A (typical GCC), group B (adenocarcinoma ex GCC, signet ring cell type), and group C (adenocarcinoma ex GCC, poorly differentiated adenocarcinoma type). In our study, we presented our population-based experience with appendiceal GCC over 30 years, examining prognostic factors and describing management and survival outcomes of patients presenting with Stage I–IV disease.3 …
Literature
1.
van Eeden S, Offerhaus GJ, Hart AA, et al. Goblet cell carcinoid of the appendix: a specific type of carcinoma. Histopathology 2007;51(6):763–73.CrossRefPubMed
2.
Tang LH, Shia J, Soslow RA, et al. Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol. 2008;32(10):1429–43.CrossRefPubMed
3.
Tsang ES, McConnell YJ, Schaeffer DF, et al. Outcomes of surgical and chemotherapeutic treatments of goblet cell carcinoid tumors of the appendix. Ann Surg Oncol. 2018; 25(8):2391–9.CrossRefPubMed
4.
Lamarca A, Nonaka D, Lopez Escola C, et al. Appendiceal goblet cell carcinoids: Management considerations from a reference peritoneal tumour service centre and ENETS centre of excellence. Neuroendocrinology. 2016;103(5):500–17.CrossRefPubMed
Metadata
Title
ASO Author Reflections: Outcomes of Appendiceal Goblet Cell Carcinoid Tumors
Authors
Erica S. Tsang, MD
Hagen F. Kennecke, MD, MHA, FRCPC
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2018
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-018-6980-x

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