Published in:
01-12-2017 | Gastrointestinal Oncology
Comment on: External Validation of the Simplified Preoperative Assessment for Low-Grade Mucinous Adenocarcinoma of the Appendix
Authors:
Sean P. Dineen, MD, Richard E. Royal, MD, Paul F. Mansfield, MD, Keith F. Fournier, MD
Published in:
Annals of Surgical Oncology
|
Special Issue 3/2017
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Excerpt
We read with much interest the article by Milovanov et al. that was recently published in
Annals of Surgical Oncology. 1 The authors reported an external validation of a simple scoring system we had previously published for determining the likelihood of a complete cytoreduction in patients with low-grade mucinous adenocarcinoma of the appendix (the SPAAT score).
2 In this external validation, there was a notable difference in the positive predictive value (PPV) of the SPAAT score compared with our original publication (50% vs. 95%). In addition, the authors noted a negative predictive value (NPV) of 90%, indicating that a SPAAT score ≥ 3 predicted failure to achieve a complete cytoreduction. The authors conclude that the SPAAT score has limited clinical utility due to low sensitivity and PPV. …
