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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2017

01-12-2017 | Hepatobiliary Tumors

Reply: YAP is a Key Factor to Improve the Management of Cancer Treatments

Authors: Ping-Li Sun, MD, PhD, Yan Jin, MD, Jin-Haeng Chung, MD, PhD

Published in: Annals of Surgical Oncology | Special Issue 3/2017

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Excerpt

We extend our appreciation to Liu et al. for their collegial interest and their comments regarding our recent publication “Cytoplasmic YAP expression is associated with prolonged survival in patients with lung adenocarcinomas and epidermal growth factor receptor tyrosine kinase inhibitor treatment.”1 …
Literature
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Sun PL, Kim JE, Yoo SB, et al. Cytoplasmic YAP expression is associated with prolonged survival in patients with lung adenocarcinomas and epidermal growth factor receptor tyrosine kinase inhibitor treatment. Ann Surg Oncol. 2014;21 Suppl 4:S610–18.CrossRefPubMed
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Oren M, Aylon Y (2013) The Hippo signaling pathway and cancer. Springer, New York.CrossRef
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Huang J, Wu S, Barrera J, Matthews K, Pan D. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell. 2005;122:421–34.CrossRefPubMed
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Basu S, Totty NF, Irwin MS, Sudol M, Downward J. Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell. 2003;11:11–23.CrossRefPubMed
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Harvey KF, Zhang X, Thomas DM. The Hippo pathway and human cancer. Nat Rev Cancer. 2013;13:246–57.CrossRefPubMed
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Liu JY, Li YH, Lin HX, et al. Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder. BMC Cancer. 2013;13:349.CrossRefPubMedPubMedCentral
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Xia Y, Chang T, Wang Y, et al. YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients. PLoS ONE. 2014;9:e91770.CrossRefPubMedPubMedCentral
Metadata
Title
Reply: YAP is a Key Factor to Improve the Management of Cancer Treatments
Authors
Ping-Li Sun, MD, PhD
Yan Jin, MD
Jin-Haeng Chung, MD, PhD
Publication date
01-12-2017
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2017
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-017-6205-8

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