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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 9/2016

01-09-2016 | Gynecologic Oncology

The Survival Rate and Surgical Morbidity of Abdominal Radical Trachelectomy Versus Abdominal Radical Hysterectomy for Stage IB1 Cervical Cancer

Authors: Xiaoqi Li, MD, Jin Li, MD, Hao Wen, MD, Xingzhu Ju, MD, PhD, Xiaojun Chen, MD, PhD, Lingfang Xia, MD, Guihao Ke, MD, PhD, Jia Tang, MD, Xiaohua Wu, MD, PhD

Published in: Annals of Surgical Oncology | Issue 9/2016

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Abstract

Purpose

To compare the survival rates and morbidities of abdominal radical trachelectomy (ART) to abdominal radical hysterectomy (ARH) for stage IB1 cervical cancer and to evaluate the safety of ART for tumors measuring 2–4 cm.

Methods

We performed a retrospective study to compare the outcomes of patients with stage IB1 cervical cancer who underwent ART to patients treated with ARH who met the inclusion criteria of a fertility-sparing surgery. All of the patients were treated by the same surgeon at our institution in the same period.

Results

Of the 107 and 141 patients who underwent ART and ARH, respectively, 61 and 82 patients had a tumor ≥2 cm (P = NS). With a median follow-up of 30 and 49 months, 2 patients treated with ART and 3 patients treated with ARH recurred: the 5-year RFS rate was 96.5 and 94.8%, respectively, for tumors ≥2 cm (P = NS). Only 3 patients died in the ARH group: the 5-year OS rate was 100% for the ART and 94.8% for the ARH group for tumors ≥2 cm (P = NS). Incidence rates of intraoperative complications were similar in the two groups (1.9% for ART and 0.7% for ARH, P = NS). However, incidence rates of postoperative complications were higher in the ART group (36.4% for ART and 19.1% for ARH, P < 0.05).

Conclusions

ART appears to have equal survival rates to ARH and can be performed safely in stage IB1 cervical cancers ≥2 cm. However, ART is associated with more postoperative morbidities compared with ARH.
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Metadata
Title
The Survival Rate and Surgical Morbidity of Abdominal Radical Trachelectomy Versus Abdominal Radical Hysterectomy for Stage IB1 Cervical Cancer
Authors
Xiaoqi Li, MD
Jin Li, MD
Hao Wen, MD
Xingzhu Ju, MD, PhD
Xiaojun Chen, MD, PhD
Lingfang Xia, MD
Guihao Ke, MD, PhD
Jia Tang, MD
Xiaohua Wu, MD, PhD
Publication date
01-09-2016
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 9/2016
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-016-5216-1

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