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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 7/2014

Open Access 01-07-2014 | Breast Oncology

Prospective Study Evaluating Oncological Safety of Axillary Reverse Mapping

Authors: Eduardo Schunemann Jr., MD, Maíra Teixeira Dória, MD, Janiceli Blanca Carlotto Hablich Silvestre, MD, Plínio Gasperin Jr., PhD, Teresa Cristina Santos Cavalcanti, PhD, Vinicius Milani Budel, PhD

Published in: Annals of Surgical Oncology | Issue 7/2014

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Abstract

Background

Axillary reverse mapping (ARM) is a new technique developed with the aim of reducing lymphedema rates by preserving lymphatic drainage of the upper limbs during sentinel lymph node biopsy and axillary lymph node dissection (ALND). However, it is unclear whether preservation of these lymph nodes affects oncological risk. The present study evaluated the presence of metastases in ARM nodes.

Methods

A total of 45 patients underwent ARM during ALND. Blue dye was used for ARM nodes localization. All axillary lymph nodes, including ARM nodes, were removed and sent separately for pathological evaluation of metastases.

Results

ARM identification was achieved in 40/45 patients (88.9 %). The average number of removed ARM nodes was 1.9. ARM nodes metastasis occurred in 10 of 40 patients (25 %). Patients with an axilla extensively affected by cancer had an elevated risk of metastasis to the arm’s lymph nodes (p < 0.001).

Conclusions

The rate of arm lymph nodes compromised by metastases calls into question the viability of the ARM technique. Larger studies may point to particular patient profiles for which ARM can be safely use.
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Metadata
Title
Prospective Study Evaluating Oncological Safety of Axillary Reverse Mapping
Authors
Eduardo Schunemann Jr., MD
Maíra Teixeira Dória, MD
Janiceli Blanca Carlotto Hablich Silvestre, MD
Plínio Gasperin Jr., PhD
Teresa Cristina Santos Cavalcanti, PhD
Vinicius Milani Budel, PhD
Publication date
01-07-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 7/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-014-3626-5

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