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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 5/2014

01-05-2014 | Head and Neck Oncology

Statistical Analysis of Surgical Site Infection After Head and Neck Reconstructive Surgery

Authors: Kenichi Kamizono, MD, Minoru Sakuraba, MD, PhD, Shogo Nagamatsu, MD, PhD, Shimpei Miyamoto, MD, PhD, Ryuichi Hayashi, MD

Published in: Annals of Surgical Oncology | Issue 5/2014

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Abstract

Background

Surgical site infections (SSIs) occur at a rate exceeding 40 % after head and neck reconstruction and are due in part to the clean-contaminated surgical field, in which cutaneous fields interact with oral or pharyngeal fields. The aim of this study was to clarify the most important risk factors for SSI and to identify effective strategies for preventing SSI.

Methods

In 2011 and 2012, 197 patients who underwent head and neck reconstructive surgery were studied at National Cancer Center Hospital East, Japan. The SSI rate, risk factors for SSI, and biological aspects of SSI were evaluated prospectively.

Results

A total of 42 patients (21.3 %) had SSIs, and 62 bacterial species were identified at infection sites. Significant risk factors for SSI identified with multivariate analysis were hypoalbuminemia [P = 0.002, odds ratio (OR) = 3.37], reconstruction with vascularized bone transfer (P = 0.006, OR = 3.99), and a poor American Society of Anesthesiologists Physical Status score (P = 0.041, OR = 3.00). Most bacteria identified were species that persist around cutaneous and pharyngeal fields, but multidrug-resistant bacteria were rare.

Conclusions

The SSI rate at our hospital is lower than rates in previous studies. To minimize SSI, intervention to improve the patient’s perisurgical nutritional status and a more appropriate mandible reconstructive strategy should be considered.
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Metadata
Title
Statistical Analysis of Surgical Site Infection After Head and Neck Reconstructive Surgery
Authors
Kenichi Kamizono, MD
Minoru Sakuraba, MD, PhD
Shogo Nagamatsu, MD, PhD
Shimpei Miyamoto, MD, PhD
Ryuichi Hayashi, MD
Publication date
01-05-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 5/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-014-3498-8

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