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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 1/2014

01-01-2014 | Reconstructive Oncology

A Systematic Review of Complications of Implant-based Breast Reconstruction with Prereconstruction and Postreconstruction Radiotherapy

Authors: Adeyiza O. Momoh, MD, Raouf Ahmed, BSc, Hons, Brian P. Kelley, MD, Oluseyi Aliu, MD, Kelley M. Kidwell, PhD, Jeffrey H. Kozlow, MD, Kevin C. Chung, MD, MS

Published in: Annals of Surgical Oncology | Issue 1/2014

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Abstract

Purpose

To conduct a systematic review of the literature to assess outcomes data on complications associated with implant-based breast reconstruction performed before or after chest wall radiation to assist in guiding the decision-making process for reconstruction of the irradiated breast.

Methods

Studies from a PubMed search that met predetermined inclusion criteria were identified and included. Complications of interest were low- and high-grade capsular contractures, minor and major complications, reconstruction failure rates, and reconstruction completion rates. Pooled complication rates were calculated.

Results

A total of 26 articles were included in the study after screening 1,006 publications, with 14 studies presenting data on prereconstruction radiation and 23 studies presenting data on postreconstruction radiation. Complication rates evaluated in patients exposed to radiation before or after implant reconstruction were not significantly different. Reconstruction failure rates were similar at 19 and 20 % for pre- and postreconstruction radiation patients, respectively. Completion rates were similar at 83 and 80 % for pre- and postreconstruction radiation patients, respectively.

Conclusions

Review of the current literature suggests similar overall success and failure rates with radiotherapy provided both before and after reconstruction. Failure rates in both groups of patients are clinically significant when considering implant reconstruction in the setting of radiation.
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Metadata
Title
A Systematic Review of Complications of Implant-based Breast Reconstruction with Prereconstruction and Postreconstruction Radiotherapy
Authors
Adeyiza O. Momoh, MD
Raouf Ahmed, BSc, Hons
Brian P. Kelley, MD
Oluseyi Aliu, MD
Kelley M. Kidwell, PhD
Jeffrey H. Kozlow, MD
Kevin C. Chung, MD, MS
Publication date
01-01-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 1/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-013-3284-z

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