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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 2/2012

01-02-2012 | Breast Oncology

The Influence of Preoperative MRI on Breast Cancer Treatment

Authors: Benjamin T. Miller, MD, Andrea M. Abbott, MD, Todd M. Tuttle, MD, MS

Published in: Annals of Surgical Oncology | Issue 2/2012

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Abstract

Background

Breast magnetic resonance imaging (MRI) is increasingly used for breast cancer treatment planning. The aim of this study was to evaluate rates of mastectomy and breast-conserving surgery (BCS) in patients who undergo preoperative MRI.

Methods

We retrospectively reviewed charts of patients who underwent surgical treatment of breast cancer at a single center between 2002 and 2009. Exclusion criteria included stage IV disease, previous breast cancer, Hodgkin lymphoma, and positive BRCA status. Univariate and multivariate analysis evaluated differences in patient demographics, surgical management, and tumor characteristics among women who underwent mastectomy compared to BCS.

Results

Patients who underwent MRI were more likely to have mastectomy than those without MRI (43 vs. 28%; P = 0.002). Multivariate analysis revealed that younger age, larger tumor size, positive lymph node status, infiltrating lobular carcinoma, and preoperative MRI were independent predictors for mastectomy (P < 0.05). MRI detected occult contralateral breast cancer in 2.7% of patients. Among patients treated with BCS, preoperative MRI was not significantly associated with lower reexcision rates (MRI, 14%; no MRI, 18%; P = 0.34).

Conclusions

Preoperative MRI was associated with higher rates of mastectomy and detection of occult contralateral breast cancer, but was not associated with lower reexcision rates.
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Metadata
Title
The Influence of Preoperative MRI on Breast Cancer Treatment
Authors
Benjamin T. Miller, MD
Andrea M. Abbott, MD
Todd M. Tuttle, MD, MS
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 2/2012
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-011-1932-8

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