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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 2/2011

01-02-2011 | Head and Neck Oncology

Feasibility of Preservation of the Submandibular Gland During Neck Dissection in Patients With Early-Stage Oral Cancer

Authors: Tseng-Cheng Chen, MD, Pei-Jen Lou, MD, PhD, Jenq-Yuh Ko, MD, PhD, Tsung-Lin Yang, MD, PhD, Wu-Chia Lo, MD, Ya-Ling Hu, RN, MSc, Cheng-Ping Wang, MD

Published in: Annals of Surgical Oncology | Issue 2/2011

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Abstract

Background

The impact of submandibular gland (SMG) preservation during neck dissection on the survival of patients with early-stage oral squamous-cell carcinoma (OSCC) remains undocumented.

Methods

The medical records of all patients with early-stage OSCC (stage I and II) who underwent wide excision of the primary tumor and simultaneous neck dissection between 1999 and 2006 at our facility were retrospectively reviewed.

Results

We analyzed 408 patients, including 33 patients with and 375 patients without SMG preservation. The 5-year disease-free and overall survival rates were 78.8% and 90.9% for the patients with SMG preservation and 75.4% and 90.4% for the patients without SMG preservation, and these differences were not statistically significant (P = 0.79, P = 0.99, respectively). Similar survival rates between patients with and without SMG preservation were observed in those with oral tongue squamous-cell carcinoma (SCC) and with buccal SCC. Patients with T2 OSCC with SMG preservation had significantly lower 5-year disease-free survival rate than those without SMG preservation (P = 0.02), but overall survival rates were similar between these two groups.

Conclusions

Preservation of the SMG during neck dissection may be oncologically safe in patients with T1 OSCC, but the feasibility of SMG preservation seems less clear for T2 OSCC.
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Metadata
Title
Feasibility of Preservation of the Submandibular Gland During Neck Dissection in Patients With Early-Stage Oral Cancer
Authors
Tseng-Cheng Chen, MD
Pei-Jen Lou, MD, PhD
Jenq-Yuh Ko, MD, PhD
Tsung-Lin Yang, MD, PhD
Wu-Chia Lo, MD
Ya-Ling Hu, RN, MSc
Cheng-Ping Wang, MD
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 2/2011
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-010-1294-7

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