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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 2/2011

01-02-2011 | Endocrine Tumors

Disease-Free Survival and Time Bias in Long-Term Follow-Up After Complete Resection of Localized Well-Differentiated Cancer

Authors: Andreas Machens, MD, Henning Dralle, MD

Published in: Annals of Surgical Oncology | Issue 2/2011

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Excerpt

Recently, Vorburger et al. presented a “long-term follow-up after complete resection of well-differentiated cancer confined to the thyroid gland.”1 To create a “highly selected group of 186 patients with macroscopically localized disease and microscopically confirmed complete resection of the carcinoma,” patients with evidence of tumor extension beyond the thyroid capsule, positive margins, enlarged lymph nodes, or distant metastasis were excluded. Institutional follow-up was complete for 166 patients who underwent various operations between 1972 and 1990. …
Literature
1.
Vorburger SA, Übersax L, Schmid SW, Balli M, Candinas D, Seiler CA. Long-term follow-up after complete resection of well-differentiated cancer confined to the thyroid gland. Ann Surg Oncol. 2009;16:2862–74.CrossRefPubMed
2.
Machtay M, Glatstein E. Editorial: Just another statistic. Oncologist 1998;3:III–IV.
3.
Feinstein AR, Sosin DM, Wells CK. The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer. N Engl J Med. 1985;312:1604–8.CrossRefPubMed
Metadata
Title
Disease-Free Survival and Time Bias in Long-Term Follow-Up After Complete Resection of Localized Well-Differentiated Cancer
Authors
Andreas Machens, MD
Henning Dralle, MD
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 2/2011
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-010-1205-y

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