Published in:
01-04-2008 | Gastrointestinal Oncology
Selection for Resection of Hepatocellular Carcinoma and Surgical Strategy: Indications for Resection, Evaluation of Liver Function, Portal Vein Embolization, and Resection
Authors:
Dario Ribero, MD, Steven A. Curley, MD, Hiroshi Imamura, MD, David C. Madoff, MD, David M. Nagorney, MD, Kelvin K. Ng, MD, PhD, Matteo Donadon, MD, Valerie Vilgrain, MD, Guido Torzilli, MD, PhD, Mark Roh, MD, Jean-Nicolas Vauthey, MD
Published in:
Annals of Surgical Oncology
|
Issue 4/2008
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Excerpt
Among the potentially curative treatment options for hepatocellular carcinoma (HCC), liver resection is widely considered the mainstay of curative therapy. An important aspect of the morbidity, mortality, and long-term outcome of liver resection for HCC relates to patient selection. Choice of treatment primarily depends on tumor stage and the functional status of the liver because most patients with HCC harbor chronic liver disease.
1 For this reason, when compared with percutaneous ablation therapies or transarterial chemoembolization (TACE), surgery has a higher risk as a result of removal of functioning liver parenchyma. Careful assessment of the clinical severity of cirrhosis and the liver functional reserve is therefore pivotal to ensure suitable selection of appropriate candidates for resection. …
