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Annals of Surgical Oncology

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01-12-2007 | Gastrointestinal Oncology

Predictors of Early Postoperative Quality of Life after Elective Resection for Colorectal Cancer

Authors: A. Sharma, MRCS, MS, D. M. Sharp, PhD, L. G. Walker, MA, PhD, J. R. T. Monson, MD, FRCS

Published in: Annals of Surgical Oncology | Issue 12/2007

Abstract

Introduction

Measurement of quality of life (QoL) is assuming increasing importance in cancer care. Predictors of early postoperative QoL after colorectal cancer resection are not clear and the aim of this study was to identify these factors.

Methods

A consecutive series of eligible patients undergoing elective resection for colorectal cancer were invited to participate. Standardised, reliable and validated psychological questionnaires (HADS, PANAS, MRS, FACT-C, EQ-5D) were administered seven days prior to surgery and then six weeks after discharge.

Results

One hundred and four patients with colorectal cancer were recruited. There were 70 males (67.3%) and the mean age of the group was 67.6 years. Postoperative anxiety and depression were closely related to the preoperative anxiety and depression scores (p < 0.001). Other QoL scores also showed significant correlation with the respective preoperative scores. Anxiety, depression, and FACT functional wellbeing scores were also correlated with the incidence of postoperative morbidity. On multiple regression analysis postoperative morbidity, tumour node metastasis (TNM) stage, presence of stoma and preoperative QoL scores were found to independently predict postoperative QoL scores.

Conclusion

Routine preoperative QoL measurement in cancer patients can identify patients at risk of having a poor QoL postoperatively. Suitable psychological and pharmaceutical intervention can be planned in advance for this group.

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Title: Predictors of Early Postoperative Quality of Life after Elective Resection for Colorectal Cancer
Authors: A. Sharma, MRCS, MS
D. M. Sharp, PhD
L. G. Walker, MA, PhD
J. R. T. Monson, MD, FRCS
Publication date: 01-12-2007
Publisher: Springer-Verlag
Published in: Annals of Surgical Oncology / Issue 12/2007
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-007-9554-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Predictors of Early Postoperative Quality of Life after Elective Resection for Colorectal Cancer

Abstract

Introduction

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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