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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 10/2007

01-10-2007 | Hepatobiliary and Pancreatic Cancer

Biliary Obstruction in Gall Bladder Cancer Is Not Sine Qua Non of Inoperability

Authors: Anil K. Agarwal, MS, MCh, Sanjoy Mandal, MS, MCh, Shivendra Singh, MS, MCh, Rajesh Bhojwani, MS, MCh, Puja Sakhuja, MD, Rajeev Uppal, MD

Published in: Annals of Surgical Oncology | Issue 10/2007

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Abstract

Background

The presence of biliary obstruction in patients with gallbladder cancer (GBC) is generally viewed as an indicator of advanced disease, inoperability and poor prognosis.

Methods

Data was collected from patients with GBC with obstructive jaundice who underwent resection during the period January 2001 to October 2003. Systematic analysis of prospective data was undertaken; patients were analyzed for resectability, post-operative morbidity, mortality and disease-free survival.

Results

During this period 14 patients with GBC with biliary obstruction underwent resection with curative intent. In these jaundiced patients, the resectability rate was 27.45% (14 of 51). In the jaundiced group the mortality was 7.14% the morbidity rate 50%, the mean disease free survival was 23.46 months (median 26 months and range of 2 to 62 months). Seven patients (50%) survived more than two years.

Conclusion

Biliary obstruction in gall bladder cancer is not sine qua non of inoperability and resection results in meaningful prolongation of survival.
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Metadata
Title
Biliary Obstruction in Gall Bladder Cancer Is Not Sine Qua Non of Inoperability
Authors
Anil K. Agarwal, MS, MCh
Sanjoy Mandal, MS, MCh
Shivendra Singh, MS, MCh
Rajesh Bhojwani, MS, MCh
Puja Sakhuja, MD
Rajeev Uppal, MD
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 10/2007
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-007-9456-y

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