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Published in:

01-02-2007

Prognostic Factors for Pulmonary Metastasectomy in Hepatocellular Carcinoma

Authors: Shuenn-Wen Kuo, Yih-Leong Chang, Pei-Ming Huang, Hsao-Hsun Hsu, Jin-Shin Chen, Jang-Ming Lee, Po-Huang Lee, Yung-Chie Lee

Published in: Annals of Surgical Oncology | Issue 2/2007

Abstract

Purpose

To identify the prognostic factors for pulmonary metastasectomy (PM-ectomy) in hepatocellular carcinoma (HCC).

Patients and methods

We conducted a retrospective review of patients with pulmonary metastases (PM) from HCC who had undergone curative PM-ectomy at National Taiwan University Hospital between 1990 and 2004. Univariate (log-rank) and multivariate (Cox’s model) analyses of survival were used to identify the significant prognostic factors.

Results

In total, 34 patients were eligible for curative PM-ectomy. The overall survival rates (Kaplan-Meier) after PM-ectomy were 65.2% and 27.5% at 2 and 5 years, respectively. High alpha-fetoprotein level, positive hepatic resection margin, and short disease-free interval (DFI) were unfavorable factors for overall survival from univariate analysis, however, only DFI (P = 0.028) was identified as an independently prognostic factor by multivariate analysis. Bilateral distribution and more PMs were unfavorable factors for PM-free survival from univariate analysis, with only PM number identified as an independent prognostic factor by multivariate analysis (P = 0.017).

Conclusion

Patients with longer DFIs and fewer PMs can benefit from PM-ectomy in HCC.

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Title: Prognostic Factors for Pulmonary Metastasectomy in Hepatocellular Carcinoma
Authors: Shuenn-Wen Kuo
Yih-Leong Chang
Pei-Ming Huang
Hsao-Hsun Hsu
Jin-Shin Chen
Jang-Ming Lee
Po-Huang Lee
Yung-Chie Lee
Publication date: 01-02-2007
Publisher: Springer-Verlag
Published in: Annals of Surgical Oncology / Issue 2/2007
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-006-9217-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Prognostic Factors for Pulmonary Metastasectomy in Hepatocellular Carcinoma

Abstract

Purpose

Patients and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Patients and methods

Results

Conclusion

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