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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 1/2007

01-01-2007

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Peritoneal Surface Malignancies of Colonic Origin: A Consensus Statement

Authors: J. Esquivel, R. Sticca, P. Sugarbaker, E. Levine, T. D. Yan, R. Alexander, D. Baratti, D. Bartlett, R. Barone, P. Barrios, S. Bieligk, P. Bretcha-Boix, C. K. Chang, F. Chu, Q. Chu, S. Daniel, E. de Bree, M. Deraco, L. Dominguez-Parra, D. Elias, R. Flynn, J. Foster, A. Garofalo, F. N. Gilly, O. Glehen, A. Gomez-Portilla, L. Gonzalez-Bayon, S. Gonzalez-Moreno, M. Goodman, V. Gushchin, N. Hanna, J. Hartmann, L. Harrison, R. Hoefer, J. Kane, D. Kecmanovic, S. Kelley, J. Kuhn, J. LaMont, J. Lange, B. Li, B. Loggie, H. Mahteme, G. Mann, R. Martin, R. A. Misih, B. Moran, D. Morris, L. Onate-Ocana, N. Petrelli, G. Philippe, J. Pingpank, A. Pitroff, P. Piso, M. Quinones, L. Riley, L. Rutstein, S. Saha, S. Alrawi, A. Sardi, S. Schneebaum, P. Shen, D. Shibata, J. Spellman, A. Stojadinovic, J. Stewart, J. Torres-Melero, T. Tuttle, V. Verwaal, J. Villar, N. Wilkinson, R. Younan, H. Zeh, F. Zoetmulder, G. Sebbag

Published in: Annals of Surgical Oncology | Issue 1/2007

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Excerpt

Surgical resection remains the hallmark therapy for primary colon cancer. It allows the patients to become clinically disease free, provides proper staging, and determines who should receive adjuvant systemic chemotherapy. Treatment options for patients with unresectable metastatic disease have improved significantly in the past few years. A review of the published data in the treatment of patients with stage IV colorectal cancer, outlining the surgical and medical therapeutic options demonstrates that medical management, with combinations of cytotoxic chemotherapy, and/or biological agents, has resulted in an unprecedented median survival>20 months. However, these therapeutic combinations are not an optimal therapeutic strategy for all categories of stage IV disease. Systemic treatment alone is no longer appropriate for patients with limited peritoneal dissemination from a primary or recurrent colon cancer. The surgical management of peritoneal surface malignancies of colonic origin with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) has been clearly defined and continues to improve. Better surgical techniques that include peritonectomy procedures, standardized methods to deliver intraoperative hyperthermic intraperitoneal chemotherapy and better patient selection criteria, have resulted in a significant improvement in survival and in morbidity and mortality of the surgical management of this particular group of stage IV colon cancer patients. …
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Metadata
Title
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Peritoneal Surface Malignancies of Colonic Origin: A Consensus Statement
Authors
J. Esquivel
R. Sticca
P. Sugarbaker
E. Levine
T. D. Yan
R. Alexander
D. Baratti
D. Bartlett
R. Barone
P. Barrios
S. Bieligk
P. Bretcha-Boix
C. K. Chang
F. Chu
Q. Chu
S. Daniel
E. de Bree
M. Deraco
L. Dominguez-Parra
D. Elias
R. Flynn
J. Foster
A. Garofalo
F. N. Gilly
O. Glehen
A. Gomez-Portilla
L. Gonzalez-Bayon
S. Gonzalez-Moreno
M. Goodman
V. Gushchin
N. Hanna
J. Hartmann
L. Harrison
R. Hoefer
J. Kane
D. Kecmanovic
S. Kelley
J. Kuhn
J. LaMont
J. Lange
B. Li
B. Loggie
H. Mahteme
G. Mann
R. Martin
R. A. Misih
B. Moran
D. Morris
L. Onate-Ocana
N. Petrelli
G. Philippe
J. Pingpank
A. Pitroff
P. Piso
M. Quinones
L. Riley
L. Rutstein
S. Saha
S. Alrawi
A. Sardi
S. Schneebaum
P. Shen
D. Shibata
J. Spellman
A. Stojadinovic
J. Stewart
J. Torres-Melero
T. Tuttle
V. Verwaal
J. Villar
N. Wilkinson
R. Younan
H. Zeh
F. Zoetmulder
G. Sebbag
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 1/2007
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-006-9185-7

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