Published in:
01-09-2021 | Metastasis | ASO Author Reflections
ASO Author Reflections: Additional Esophagectomy After Noncurative Endoscopic Resection Versus Upfront Esophagectomy in Patients with T1N0 Esophageal Squamous Cell Carcinoma
Authors:
Suguru Maruyama, MD, PhD, Akihiko Okamura, MD, PhD, Masayuki Watanabe, MD, PhD
Published in:
Annals of Surgical Oncology
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Issue 9/2021
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Excerpt
Esophagectomy with lymph node dissection is currently regarded as the standard treatment after noncurative endoscopic resection (ER), based on several retrospective analyses consisting of a limited number of cases.
1–3 Meanwhile, a recent prospective trial revealed the efficacy of the combination of ER and selected chemoradiotherapy (CRT) for T1b (SM1-2) N0 esophageal squamous cell carcinoma (ESCC).
4 Currently, an optimal treatment modality for the additional treatment of patients after noncurative ER remains unclear as there are no randomized controlled trials. Few studies elucidated the clinical features of additional esophagectomy for patients after noncurative ER when compared with upfront esophagectomy for T1N0 ESCC. Furthermore, the difference in the incidence, distribution, and number of lymph node metastases between both remain unknown. …
