Published in:
01-08-2021 | Mastectomy | ASO Author Reflections
ASO Author Reflections: Do Shorter Tumor-to-Nipple Distances Compromise the Local Oncologic Safety of Nipple-Sparing Mastectomy?
Authors:
Zhen-Yu Wu, MD, PhD, Jing Han, MD, Jin Sup Eom, MD, PhD, Sei-Hyun Ahn, MD, PhD, BeomSeok Ko, MD, PhD
Published in:
Annals of Surgical Oncology
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Issue 8/2021
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Excerpt
The indications for therapeutic nipple-spring mastectomy (NSM) remain controversial, particularly in terms of the tumor-to-nipple distance (TND). A short TND strongly predicts nipple–areola complex (NAC) involvement.
1 Accordingly, several past NSM series excluded patients with a TND shorter than 2 cm or less than 1 cm from the NSM considering the increased risk of occult nipple involvement.
2,3 Dent et al.
4 reported no significant differences in NAC involvement risk between a TND of 1 cm or less and a TND greater than 1 cm after NSM (measured using preoperative magnetic resonance imaging or ultrasonography) and suggested that a TND of 1 cm or less is not a contraindication to NSM. However, whether a short TND is subsequently associated with an increased risk of recurrence at NAC or detrimental to overall local oncologic safety after a successful NSM with a negative retroareolar resection margin remains unclear because the long-term follow-up data on local recurrence outcomes are insufficient. …
