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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2020

01-03-2020 | Esophageal Cancer | ASO Author Reflections

ASO Author Reflections: Lymphadenectomy in Esophagectomy: Why Bother?

Authors: Alexander W. Phillips, MD, MA, Sivesh K. Kamarajah, BMedSci, MBChB

Published in: Annals of Surgical Oncology | Issue 3/2020

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Excerpt

There has been much debate regarding the necessity of lymphadenectomy in treating esophageal cancer. While some acknowledge its importance in improved staging, others have argued that it conveys no curative benefit. Neoadjuvant therapy for patients with locally advanced disease is recognized as standard practice to address any potential disease spread.1 However, the extent of lymphadenectomy has previously been conflated with the number of nodes removed, and the two are not the same. Previous studies have shown benefit for a thorough lymphadenectomy in patients receiving neoadjuvant treatment.2,3 What of the patients who have early disease and do not receive this, or where neoadjuvant treatment is contraindicated? …
Literature
1.
Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE. Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol. 2009;27(30):5062–7.CrossRef
2.
Visser E, Markar SR, Ruurda JP, Hanna GB, van Hillegersberg R. Prognostic value of lymph node yield on overall survival in esophageal cancer patients. Ann Surg. 2018;269:261–8.CrossRef
3.
Phillips AW, Lagarde SM, Navidi M, Disep B, Griffin SM. Impact of extent of lymphadenectomy on survival, post neoadjuvant chemotherapy and transthoracic esophagectomy. Ann Surg. 2017;265(4):750–6.CrossRef
4.
Metadata
Title
ASO Author Reflections: Lymphadenectomy in Esophagectomy: Why Bother?
Authors
Alexander W. Phillips, MD, MA
Sivesh K. Kamarajah, BMedSci, MBChB
Publication date
01-03-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 3/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-08017-z

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