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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 6/2014

01-06-2014 | Gastrointestinal Oncology

Matched Pair Analysis to Examine the Effects of a Planned Preoperative Exercise Program in Early Gastric Cancer Patients with Metabolic Syndrome to Reduce Operative Risk: The Adjuvant Exercise for General Elective Surgery (AEGES) Study Group

Authors: Haruhiko Cho, MD, PhD, Takaki Yoshikawa, MD, PhD, Mari S. Oba, PhD, Naoki Hirabayashi, MD, PhD, Junya Shirai, MD, Toru Aoyama, MD, Tsutomu Hayashi, MD, Takanobu Yamada, MD, Koji Oba, PhD, Satoshi Morita, PhD, Junichi Sakamoto, MD, PhD, FACS, Akira Tsuburaya, MD, PhD

Published in: Annals of Surgical Oncology | Issue 6/2014

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Abstract

Background

Because obesity is a risk factor during surgery, the effects of a preoperative exercise program to reduce the incidence of peri- and postoperative complications in patients with a high body mass index (>25 kg/m2) and metabolic syndrome were investigated. An assessment of the effects of prospectively planned preoperative exercise was performed in a prospective matching study comparing an exercise testing group and a usual preoperative preparation group who underwent gastrectomy for gastric cancer in Japan.

Methods

Stage I gastric cancer patients with metabolic syndrome diagnosed according to the criteria of the Japanese Ministry of Health, Labor, and Welfare underwent surgery after preoperative exercise. The control group was selected from a database using an individual matching approach for surgery, sex, weight, body mass index, volume of visceral fat, and institution. The primary end point was the frequency of postoperative complications such as cardiovascular events, pneumonia, and surgery-related abdominal complications.

Results

Data from a total of 72 patients (54 in the surgery-alone group, 18 in the preoperative exercise group) were analyzed. The median operative time and amount of bleeding were 208 min and 130 ml in the surgery-alone group and 248 min and 105 ml in the exercise group, respectively. Postoperative complications occurred in one case (5.5 %) in the exercise group and 22 (40.7 %) cases in the surgery-alone group.

Conclusions

Preoperative exercise is safe, and its benefits in reducing postoperative complications are promising and therefore warrant further investigation.
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Metadata
Title
Matched Pair Analysis to Examine the Effects of a Planned Preoperative Exercise Program in Early Gastric Cancer Patients with Metabolic Syndrome to Reduce Operative Risk: The Adjuvant Exercise for General Elective Surgery (AEGES) Study Group
Authors
Haruhiko Cho, MD, PhD
Takaki Yoshikawa, MD, PhD
Mari S. Oba, PhD
Naoki Hirabayashi, MD, PhD
Junya Shirai, MD
Toru Aoyama, MD
Tsutomu Hayashi, MD
Takanobu Yamada, MD
Koji Oba, PhD
Satoshi Morita, PhD
Junichi Sakamoto, MD, PhD, FACS
Akira Tsuburaya, MD, PhD
Publication date
01-06-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 6/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-013-3394-7

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