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Maxillofacial Plastic and Reconstructive Surgery
Published in: Maxillofacial Plastic and Reconstructive Surgery 1/2019

Open Access 01-12-2019 | Nerve Injury | Research

Effect of duration from lingual nerve injury to undergoing microneurosurgery on improving sensory and taste functions: retrospective study

Authors: Takashi Nakanishi, Yuta Yamamoto, Kensuke Tanioka, Yukari Shintani, Itaru Tojyo, Shigeyuki Fujita

Published in: Maxillofacial Plastic and Reconstructive Surgery | Issue 1/2019

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Abstract

Background

The prognosis of recovery following microneurosurgery for injured lingual nerves varies among individual cases. This study aimed to investigate if recovery ratios of sensory and taste functions are improved by the microneurosurgery within 6 months after lingual nerve injury.

Methods

We retrospectively assessed 70 patients who underwent microneurosurgery at the Wakayama Medical University Hospital for lingual nerve injuries between July 2004 and December 2016. Sensory and taste functions in lingual nerves were preoperatively evaluated using a static two-point discrimination test, an intact superficial pain/tactile sensation test, and a taste discrimination test. They were evaluated again at 12 and at 24 months postoperatively. The abundance ratio of Schwann cells in the excised traumatic neuromas was analyzed with ImageJ software following immunohistochemistry with anti S-100β antibody.

Results

In early cases (microneurosurgery within 6 months after the injury), recovery ratios of sensory and taste functions were not significantly different at 24 months after microneurosurgery compared with later cases (microneurosurgery more than 6 months after the injury). Meanwhile, the ratio of patients with taste recovery within 12 months after microneurosurgery was significantly decreased in late cases compared with early cases. The abundance ratio of Schwann cells in traumatic neuroma was also significantly lower in later cases.

Conclusion

Microneurosurgery more than 6 months after lingual nerve injury did not lead to decreased recovery ratio of sensory and taste functions, but it did lead to prolonged recovery of taste. This delay may be associated with a decrease in the abundance ratio of Schwann cells in traumatic neuromas.
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Metadata
Title
Effect of duration from lingual nerve injury to undergoing microneurosurgery on improving sensory and taste functions: retrospective study
Authors
Takashi Nakanishi
Yuta Yamamoto
Kensuke Tanioka
Yukari Shintani
Itaru Tojyo
Shigeyuki Fujita
Publication date
01-12-2019
Publisher
Springer Berlin Heidelberg
Keyword
Nerve Injury
Published in
Maxillofacial Plastic and Reconstructive Surgery / Issue 1/2019
Electronic ISSN: 2288-8586
DOI
https://doi.org/10.1186/s40902-019-0244-y

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