Skip to main content
Top
Published in: Maxillofacial Plastic and Reconstructive Surgery 1/2017

Open Access 01-12-2017 | Case report

Schwannoma of the tongue: a case report with review of literature

Authors: Eun-Young Lee, Jae-Jin Kim, Hyun Seok, Ja-Youn Lee

Published in: Maxillofacial Plastic and Reconstructive Surgery | Issue 1/2017

Login to get access

Abstract

Background

Schwannomas (or neurilemmomas) of the tongue are benign, usually solitary, encapsulated masses derived from Schwann cells. Clinical evidence indicates that schwannoma is painless and slow growing. In general, schwannoma is treated by surgical excision.
Here, we describe a case of schwannoma of the tongue, include a review of the literature from 1955 to 2016, and provide data on age, gender, location, presenting symptoms, size, and treatment methods.

Case presentation

A 71-year-old female patient presented with a swelling at the base of the tongue of unknown duration. Magnetic resonance images (MRI) showed a large well-circumscribed solid mass and no significant lymph node enlargement. The mass was excised without removing overlying mucosa.

Conclusions

The authors report a case of lingual schwannoma that was completely removed intraorally without preoperative biopsy. No sign or symptoms of recurrence were observed at 12 months postoperatively.
Literature
1.
go back to reference Harada H, Omura K, Maeda A (2001) A massive pleomorphic adenoma of the submandibular salivary gland accompanied by neurilemomas of the neck misdiagnosed as a malignant tumor: report of case. J Oral Maxillofac Surg 59:931–935CrossRefPubMed Harada H, Omura K, Maeda A (2001) A massive pleomorphic adenoma of the submandibular salivary gland accompanied by neurilemomas of the neck misdiagnosed as a malignant tumor: report of case. J Oral Maxillofac Surg 59:931–935CrossRefPubMed
2.
go back to reference de Bree R, Westerveld G, Smeele L (2000) Submandibular approach for excision of a large schwannoma in the base of the tongue. Eur Arch Otorhinolaryngol 257:283–286CrossRefPubMed de Bree R, Westerveld G, Smeele L (2000) Submandibular approach for excision of a large schwannoma in the base of the tongue. Eur Arch Otorhinolaryngol 257:283–286CrossRefPubMed
3.
go back to reference Nelson W, Chuprevich T, Galbraith D (1988) Enlarging tongue mass. J Oral Maxillofac Surg 56:224–227CrossRef Nelson W, Chuprevich T, Galbraith D (1988) Enlarging tongue mass. J Oral Maxillofac Surg 56:224–227CrossRef
4.
go back to reference George N, Wagh M, Balgopal P, Gupta A, Sukumaran R, Sebastian P (2014) Schwannoma base tongue: case report and review of literature. Gulf J Oncolog 16:94–100 George N, Wagh M, Balgopal P, Gupta A, Sukumaran R, Sebastian P (2014) Schwannoma base tongue: case report and review of literature. Gulf J Oncolog 16:94–100
5.
go back to reference Lira RB, Filho G, Carvalho GB, Pinto CA, Kowalski LP (2013) Lingual schwannoma: case report and review of the literature. Acta Otorhinolaryngol Ital 33:137–140PubMedPubMedCentral Lira RB, Filho G, Carvalho GB, Pinto CA, Kowalski LP (2013) Lingual schwannoma: case report and review of the literature. Acta Otorhinolaryngol Ital 33:137–140PubMedPubMedCentral
6.
go back to reference Arda H, Akdogan O, Arda N, Sarikaya Y (2003) An unusual site for an intraoral schwannoma: a case report. Am J Otolaryngol 24:348–50CrossRefPubMed Arda H, Akdogan O, Arda N, Sarikaya Y (2003) An unusual site for an intraoral schwannoma: a case report. Am J Otolaryngol 24:348–50CrossRefPubMed
7.
go back to reference Hsu Y, Hwang C, Hsu R, Kuo F, Chien C (2006) Schwannoma (neurilemmoma) of the tongue. Acta Otolaryngol 126:861–865CrossRefPubMed Hsu Y, Hwang C, Hsu R, Kuo F, Chien C (2006) Schwannoma (neurilemmoma) of the tongue. Acta Otolaryngol 126:861–865CrossRefPubMed
8.
go back to reference Tsushima F, Sawai T, Kayamori K, Okada N, Omura K (2012) Schwannoma in the floor of the mouth: a case report and clinicopathological studies of 10 cases in the oral region. J Oral Maxillofac Surg Med Pathol 24:175–179CrossRef Tsushima F, Sawai T, Kayamori K, Okada N, Omura K (2012) Schwannoma in the floor of the mouth: a case report and clinicopathological studies of 10 cases in the oral region. J Oral Maxillofac Surg Med Pathol 24:175–179CrossRef
9.
go back to reference Gallo W, Moss M, Shapiro D, Gaul J (1977) Neurilemmoma: review of the literature and report of five cases. J Oral Surg 35:235–236PubMed Gallo W, Moss M, Shapiro D, Gaul J (1977) Neurilemmoma: review of the literature and report of five cases. J Oral Surg 35:235–236PubMed
10.
go back to reference Lopez J, Ballistin C (1993) Intraoral schwannoma: a clinicopathologic and immunohistochemical study of nine cases. Arch Anat Cytol Pathol 41:18–23PubMed Lopez J, Ballistin C (1993) Intraoral schwannoma: a clinicopathologic and immunohistochemical study of nine cases. Arch Anat Cytol Pathol 41:18–23PubMed
11.
go back to reference Bhola N, Jadhav A, Borle R, Khemka G, Bhutekar U, Kumar S (2014) Schwannoma of the tongue in a paediatric patient: a case report and 20-year review. Case Rep Dent. 2014;2014:780762. doi:10.1155/2014/780762 Bhola N, Jadhav A, Borle R, Khemka G, Bhutekar U, Kumar S (2014) Schwannoma of the tongue in a paediatric patient: a case report and 20-year review. Case Rep Dent. 2014;2014:780762. doi:10.​1155/​2014/​780762
12.
go back to reference Cohen L, Schwartz A, Rockoff S (1986) Benign schwannomas: pathologic basis for CT inhomogeneities. AJR 147:141–143CrossRefPubMed Cohen L, Schwartz A, Rockoff S (1986) Benign schwannomas: pathologic basis for CT inhomogeneities. AJR 147:141–143CrossRefPubMed
13.
go back to reference La'porte S, Juttla J, Lingam R (2011) Imaging the floor of the mouth and the sublingual space. Radiographics 31:1215–1230CrossRefPubMed La'porte S, Juttla J, Lingam R (2011) Imaging the floor of the mouth and the sublingual space. Radiographics 31:1215–1230CrossRefPubMed
15.
go back to reference Dreher A, Gutmann R, Grevers G (1997) Extracranial schwannoma of the ENT region. Review of the literature with a case report of benign schwannoma of the base of the tongue. HNO 45:468–471PubMed Dreher A, Gutmann R, Grevers G (1997) Extracranial schwannoma of the ENT region. Review of the literature with a case report of benign schwannoma of the base of the tongue. HNO 45:468–471PubMed
18.
go back to reference Naik S, Goutham M, Ravishankara S, Appaji M (2012) Sublingual schwannoma: a rare clinical entity reported in a hypothyroid female. Int J Head Neck Surg 3:33–39CrossRef Naik S, Goutham M, Ravishankara S, Appaji M (2012) Sublingual schwannoma: a rare clinical entity reported in a hypothyroid female. Int J Head Neck Surg 3:33–39CrossRef
19.
go back to reference Sawhney R, Carron M, Mathog R (2008) Tongue base schwannoma: report, review, and unique surgical approach. Am J Otolaryngol 29:119–122CrossRefPubMed Sawhney R, Carron M, Mathog R (2008) Tongue base schwannoma: report, review, and unique surgical approach. Am J Otolaryngol 29:119–122CrossRefPubMed
20.
21.
go back to reference Mercantini E, Mopper C (1959) Neurilemmoma of the tongue. AMA 79:542–544 Mercantini E, Mopper C (1959) Neurilemmoma of the tongue. AMA 79:542–544
22.
go back to reference Cameron I (1959) A case of neurilemmoma (schwannoma) of the tongue. Oral Surg Oral Med Oral Pathol 12:1464–1467CrossRefPubMed Cameron I (1959) A case of neurilemmoma (schwannoma) of the tongue. Oral Surg Oral Med Oral Pathol 12:1464–1467CrossRefPubMed
23.
25.
27.
go back to reference Firfer H, Sohn D, Heurlin R, Stutevile O (1966) Neurilemmoma of the tongue. Oral Surg Oral Med Oral Pathol 21:139–142CrossRefPubMed Firfer H, Sohn D, Heurlin R, Stutevile O (1966) Neurilemmoma of the tongue. Oral Surg Oral Med Oral Pathol 21:139–142CrossRefPubMed
28.
go back to reference Hatziotis J, Aspride H (1967) Neurilemmoma (schwannoma) of the oral cavity. Oral Surg Oral Med Oral Pathol 24:510–526CrossRef Hatziotis J, Aspride H (1967) Neurilemmoma (schwannoma) of the oral cavity. Oral Surg Oral Med Oral Pathol 24:510–526CrossRef
29.
go back to reference Oles R, Werthemier F (1967) Neurilemmoma of the tongue. J Mish State Dent Assoc 49:7–8 Oles R, Werthemier F (1967) Neurilemmoma of the tongue. J Mish State Dent Assoc 49:7–8
30.
go back to reference Paliwal Y, Kapur V, Singh R (1967) Neurilemmoma of the tongue. Int Surg 47:503–506PubMed Paliwal Y, Kapur V, Singh R (1967) Neurilemmoma of the tongue. Int Surg 47:503–506PubMed
31.
go back to reference Crawford W, Korcin L, Greskovich FJ (1968) Neurilemmoma of the oral cavity: report of five cases. J Oral Surg (Chic) 26:651–658CrossRef Crawford W, Korcin L, Greskovich FJ (1968) Neurilemmoma of the oral cavity: report of five cases. J Oral Surg (Chic) 26:651–658CrossRef
32.
go back to reference Das Gupta T, Brasfield R, Strong E, Hadju S (1969) Benign solitary schwannoma (neurilemmoma). Cancer 24:355–366CrossRefPubMed Das Gupta T, Brasfield R, Strong E, Hadju S (1969) Benign solitary schwannoma (neurilemmoma). Cancer 24:355–366CrossRefPubMed
33.
34.
go back to reference Sinha S, Samuel K (1971) Neurilemmoma of tongue. J Larygol Otol 85:623–626CrossRef Sinha S, Samuel K (1971) Neurilemmoma of tongue. J Larygol Otol 85:623–626CrossRef
35.
go back to reference Monsadomi A (1975) Neurilemmoma of the tongue. J Oral Med 30:44–46 Monsadomi A (1975) Neurilemmoma of the tongue. J Oral Med 30:44–46
36.
37.
go back to reference Sharan R, Akhtar M (1978) Neurilemmoma of tongue. J Indian Med Assoc 71:290–291PubMed Sharan R, Akhtar M (1978) Neurilemmoma of tongue. J Indian Med Assoc 71:290–291PubMed
38.
go back to reference Akimoto Y, Yamamoto H, Nishmura H, Komiya M, Kaneko K (1987) Neurilemmoma in the oral cavity. J Nihon Univ Sch Dent 29:203–205CrossRefPubMed Akimoto Y, Yamamoto H, Nishmura H, Komiya M, Kaneko K (1987) Neurilemmoma in the oral cavity. J Nihon Univ Sch Dent 29:203–205CrossRefPubMed
39.
go back to reference Sira C, Ng K, Chia T, Kulkarni M (1988) Atypical neurilemmoma of the tongue: report of two cases. Dent Update 29:83–85 Sira C, Ng K, Chia T, Kulkarni M (1988) Atypical neurilemmoma of the tongue: report of two cases. Dent Update 29:83–85
40.
go back to reference Flickinger F, Lozano R, Yuh W, Sachs M (1989) Neurilemmoma of the tongue: MR finding. J Comput Assist Tomgr 13:886–888CrossRef Flickinger F, Lozano R, Yuh W, Sachs M (1989) Neurilemmoma of the tongue: MR finding. J Comput Assist Tomgr 13:886–888CrossRef
41.
go back to reference Talmi Y, Gal R, Finkelstein Y, Shvilli V, Zohar Y (1991) Pathologic quiz case 1: benign schwannoma of tongue. Arch Otolaryngol Head Neck Surg 117:926–928CrossRefPubMed Talmi Y, Gal R, Finkelstein Y, Shvilli V, Zohar Y (1991) Pathologic quiz case 1: benign schwannoma of tongue. Arch Otolaryngol Head Neck Surg 117:926–928CrossRefPubMed
42.
go back to reference Gallesio C, Berrone S (1992) Schwannoma located in the tongue: a clinical case report. Minerva Somatologica 41:583–590 Gallesio C, Berrone S (1992) Schwannoma located in the tongue: a clinical case report. Minerva Somatologica 41:583–590
43.
go back to reference Haring J (1994) Case #10. Neurilemmoma. RDH 14:12–12 Haring J (1994) Case #10. Neurilemmoma. RDH 14:12–12
44.
go back to reference Nakayama H, Gobara R, Shimamot F, Kajihara H (1996) Ancient schwannoma of the oral floor and ventricular portion of the tongue: a case report and review of literature. Jpn J ClinOncol 26:185–188 Nakayama H, Gobara R, Shimamot F, Kajihara H (1996) Ancient schwannoma of the oral floor and ventricular portion of the tongue: a case report and review of literature. Jpn J ClinOncol 26:185–188
45.
go back to reference Spandow O, Frgerlund M, Bergmark L, Boquist L (1999) Clinical and histopathological features of a large parapharyngeal neurilemmoma located at the tongue. ORL J Otorhinolaryngol Relat Spec 61:25–30CrossRefPubMed Spandow O, Frgerlund M, Bergmark L, Boquist L (1999) Clinical and histopathological features of a large parapharyngeal neurilemmoma located at the tongue. ORL J Otorhinolaryngol Relat Spec 61:25–30CrossRefPubMed
46.
go back to reference Pfeifle R, Baur D, Paulino A, Helmen J (2001) Schwannoma of the tongue: report of 2 cases. J Oral Maxillofac Surg 59:802–804CrossRefPubMed Pfeifle R, Baur D, Paulino A, Helmen J (2001) Schwannoma of the tongue: report of 2 cases. J Oral Maxillofac Surg 59:802–804CrossRefPubMed
47.
go back to reference Cinar F, Cinar S, Harman G (2004) Schwannoma of the tip of the tongue in a child. Plast Reconstr Surg 114:1657–1658PubMed Cinar F, Cinar S, Harman G (2004) Schwannoma of the tip of the tongue in a child. Plast Reconstr Surg 114:1657–1658PubMed
48.
go back to reference Bassichis B, McMlay J (2004) Pedunculated neurilemmoma of the tongue base. Otolarygol Head Neck Surg 130:639–641CrossRef Bassichis B, McMlay J (2004) Pedunculated neurilemmoma of the tongue base. Otolarygol Head Neck Surg 130:639–641CrossRef
49.
go back to reference Nakasato T, Kamada Y, Ehara S, Miura Y (2005) Multilobular neurilemmoma of the tongue in the child. AJNR Am J Neuroradiol 26:421–423PubMed Nakasato T, Kamada Y, Ehara S, Miura Y (2005) Multilobular neurilemmoma of the tongue in the child. AJNR Am J Neuroradiol 26:421–423PubMed
50.
51.
go back to reference Lopez-Jornet P, Bermejo-Fenoll A (2005) Neurilemmoma of the tongue. Oral Oncology EXTRA 41:154–157CrossRef Lopez-Jornet P, Bermejo-Fenoll A (2005) Neurilemmoma of the tongue. Oral Oncology EXTRA 41:154–157CrossRef
52.
go back to reference Vafiadis M, Fiska A, Panopoulou M, Assimakopoulo D (2005) A clinical case report of a schwannoma on the tip of tongue. B-ENT 1:201–204PubMed Vafiadis M, Fiska A, Panopoulou M, Assimakopoulo D (2005) A clinical case report of a schwannoma on the tip of tongue. B-ENT 1:201–204PubMed
53.
go back to reference Bansal R, Trivedi P, Patel S (2005) Schwannoma of the tongue. Oral Oncology EXTRA 41:15–17CrossRef Bansal R, Trivedi P, Patel S (2005) Schwannoma of the tongue. Oral Oncology EXTRA 41:15–17CrossRef
54.
go back to reference Ying Y, Zimmer L, Myers E (2006) Base of tongue schwannoma: a case report. Laryngoscope 116:1284–1287CrossRefPubMed Ying Y, Zimmer L, Myers E (2006) Base of tongue schwannoma: a case report. Laryngoscope 116:1284–1287CrossRefPubMed
55.
go back to reference Mehrzad H, Persaud R, Papadimitriou N, Kaniyur S, Mochloilis G (2006) Schwannoma of tongue base treated with transoral carbon dioxide laser. Lasers Med Sci 21:235–237CrossRefPubMed Mehrzad H, Persaud R, Papadimitriou N, Kaniyur S, Mochloilis G (2006) Schwannoma of tongue base treated with transoral carbon dioxide laser. Lasers Med Sci 21:235–237CrossRefPubMed
56.
go back to reference Batra K, Rai A, Chaudhary N, Topno S (2007) Two cases of neurilemmoma of the tongue. ENT-Ear Nose Throat J 86:679–681 Batra K, Rai A, Chaudhary N, Topno S (2007) Two cases of neurilemmoma of the tongue. ENT-Ear Nose Throat J 86:679–681
57.
go back to reference Ballesteros F, Vilaseca I, Blanch J, Gaspa A, Bernal-Sprekelsen M (2007) Base of tongue neurilemmoma: excision by transoral laser microsurgery. Acta Otolaryngol 127:1005–1007CrossRefPubMed Ballesteros F, Vilaseca I, Blanch J, Gaspa A, Bernal-Sprekelsen M (2007) Base of tongue neurilemmoma: excision by transoral laser microsurgery. Acta Otolaryngol 127:1005–1007CrossRefPubMed
58.
go back to reference Sethi D, Sethi A, Nigam S, Agarwal A (2008) Schwannoma of oral tongue: a rare benign neoplasm. IHANS Vol. 3, No. 1. 8496 Sethi D, Sethi A, Nigam S, Agarwal A (2008) Schwannoma of oral tongue: a rare benign neoplasm. IHANS Vol. 3, No. 1. 8496
59.
go back to reference Pereira L, Pereira P, dos Santos JP, Reis Filho V, Dominguete PR, Pereira AA (2008) Lingual schwannoma involving the posterior lateral border of the tongue in a young individual: case report. J Clin Pediatr Dent 33:59–62CrossRefPubMed Pereira L, Pereira P, dos Santos JP, Reis Filho V, Dominguete PR, Pereira AA (2008) Lingual schwannoma involving the posterior lateral border of the tongue in a young individual: case report. J Clin Pediatr Dent 33:59–62CrossRefPubMed
60.
go back to reference Gupta P, Garg A, Dhingra K, Jain D, Kohli K, Khurana N (2009) Schwannoma tongue: a rare entity. ANZ J Surg 79:93–94CrossRefPubMed Gupta P, Garg A, Dhingra K, Jain D, Kohli K, Khurana N (2009) Schwannoma tongue: a rare entity. ANZ J Surg 79:93–94CrossRefPubMed
61.
go back to reference Mardanpour K, Rahbar M (2009) Lingual schwannoma: a case report. IRCMJ 11:454–456 Mardanpour K, Rahbar M (2009) Lingual schwannoma: a case report. IRCMJ 11:454–456
62.
go back to reference Karaca C, Habesoglu T, Naiboglu B, Habesoglu M, Oysu C, Egeli E, Tosun I (2010) Schwannoma of the tongue in a child. Am J Otolaryngol 31:46–48CrossRefPubMed Karaca C, Habesoglu T, Naiboglu B, Habesoglu M, Oysu C, Egeli E, Tosun I (2010) Schwannoma of the tongue in a child. Am J Otolaryngol 31:46–48CrossRefPubMed
63.
go back to reference Cigdem T, Tulay E, Baris N, Mehmet H, Cagatay O, Erol E, Iikay T (2010) Schwannoma of the tongue in a child. Am J Otolaryngol Head and Neck Med and Surg 31:46–48 Cigdem T, Tulay E, Baris N, Mehmet H, Cagatay O, Erol E, Iikay T (2010) Schwannoma of the tongue in a child. Am J Otolaryngol Head and Neck Med and Surg 31:46–48
64.
go back to reference Jeffcoat B, Pitman K, Brown A, Baliga M (2010) Schwannoma of the oral tongue. Laryngoscope 120(Suppl 4):S154CrossRefPubMed Jeffcoat B, Pitman K, Brown A, Baliga M (2010) Schwannoma of the oral tongue. Laryngoscope 120(Suppl 4):S154CrossRefPubMed
65.
go back to reference Naidu G, Sinha S (2010) Schwannoma of the tongue: an unusual presentation in a child. IJDR 21:457–459PubMed Naidu G, Sinha S (2010) Schwannoma of the tongue: an unusual presentation in a child. IJDR 21:457–459PubMed
66.
go back to reference Lukšić I, Müller D, Virag M, Manojlović S, Ostović K (2011) Schwannoma of the tongue in a child. J Craniomaxillofac Surg 39:441–444CrossRefPubMed Lukšić I, Müller D, Virag M, Manojlović S, Ostović K (2011) Schwannoma of the tongue in a child. J Craniomaxillofac Surg 39:441–444CrossRefPubMed
67.
go back to reference Batra U, Usha G, Gogia A (2011) Anesthetic management of schwannoma of the base of the tongue. JOACP 27:241–243 Batra U, Usha G, Gogia A (2011) Anesthetic management of schwannoma of the base of the tongue. JOACP 27:241–243
70.
go back to reference Erkul E, Cıncık H, Haholu A, Cekin E, Güngör A (2013) Schwannoma of the tongue: a report of two cases and review., OLGU SUNUMU/CASE REPORT.doi:10.5455/gulhane.39838 Erkul E, Cıncık H, Haholu A, Cekin E, Güngör A (2013) Schwannoma of the tongue: a report of two cases and review., OLGU SUNUMU/CASE REPORT.doi:10.​5455/​gulhane.​39838
71.
go back to reference Jayaraman V, Balasubramanian B, Senthivelu R (2013) Schwannoma of the tongue—a rare clinical entity. IJDSR 1:53–55 Jayaraman V, Balasubramanian B, Senthivelu R (2013) Schwannoma of the tongue—a rare clinical entity. IJDSR 1:53–55
72.
73.
go back to reference Gopalakrishnan S, Jayaraman N, Albina SAL (2016) Schwannoma over tongue base—case report and review. Otolaryngol Online J 6:1–7 Gopalakrishnan S, Jayaraman N, Albina SAL (2016) Schwannoma over tongue base—case report and review. Otolaryngol Online J 6:1–7
Metadata
Title
Schwannoma of the tongue: a case report with review of literature
Authors
Eun-Young Lee
Jae-Jin Kim
Hyun Seok
Ja-Youn Lee
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Maxillofacial Plastic and Reconstructive Surgery / Issue 1/2017
Electronic ISSN: 2288-8586
DOI
https://doi.org/10.1186/s40902-017-0116-2

Other articles of this Issue 1/2017

Maxillofacial Plastic and Reconstructive Surgery 1/2017 Go to the issue