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Translational Neurodegeneration
Published in: Translational Neurodegeneration 1/2016

Open Access 01-12-2016 | Review

Benign tremulous Parkinsonism: a unique entity or another facet of Parkinson’s disease?

Authors: Wissam Deeb, Wei Hu, Leonardo Almeida, Addie Patterson, Daniel Martinez-Ramirez, Aparna Wagle Shukla

Published in: Translational Neurodegeneration | Issue 1/2016

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Abstract

Benign tremulous parkinsonism (BTP) is characterized by a prominent tremor that occurs both at rest and with action in conjunction with other mild features of parkinsonism. The progression of symptoms is typically slow and there is often a positive family history. Although BTP is included within the phenotypic spectrum of Parkinsonism its exact relationship with idiopathic Parkinson’s disease remains unclear. Treatment of BTP is challenging especially considering the poor response to levodopa, therefore surgical therapies such as deep brain stimulation surgery are sought for treatment of these tremors. In this review, we will summarize the clinical features, diagnosis, neuropathology and treatment for BTP.
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Metadata
Title
Benign tremulous Parkinsonism: a unique entity or another facet of Parkinson’s disease?
Authors
Wissam Deeb
Wei Hu
Leonardo Almeida
Addie Patterson
Daniel Martinez-Ramirez
Aparna Wagle Shukla
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Translational Neurodegeneration / Issue 1/2016
Electronic ISSN: 2047-9158
DOI
https://doi.org/10.1186/s40035-016-0057-1

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