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Published in: European Journal of Medical Research 1/2021

Open Access 01-12-2021 | Dyspnea | Research

Predictors of the prolonged recovery period in COVID-19 patients: a cross-sectional study

Authors: SeyedAhmad SeyedAlinaghi, Ladan Abbasian, Mohammad Solduzian, Niloofar Ayoobi Yazdi, Fatemeh Jafari, Alireza Adibimehr, Aazam Farahani, Arezoo Salami Khaneshan, Parvaneh Ebrahimi Alavijeh, Zahra Jahani, Elnaz Karimian, Zahra Ahmadinejad, Hossein Khalili, Arash Seifi, Fereshteh Ghiasvand, Sara Ghaderkhani, Mehrnaz Rasoolinejad

Published in: European Journal of Medical Research | Issue 1/2021

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Abstract

Background

The clinical course of COVID-19 may vary significantly. The presence of comorbidities prolongs the recovery time. The recovery in patients with mild-to-moderate symptoms might take 10 days, while in those with a critical illness or immunocompromised status could take 15 days. Considering the lack of data about predictors that could affect the recovery time, we conducted this study to identify them.

Methods

This cross-sectional study was implemented in the COVID-19 clinic of a teaching and referral university hospital in Tehran. Patients with the highly suggestive symptoms who had computed tomography (CT) imaging results with typical findings of COVID-19 or positive results of reverse transcriptase-polymerase chain reaction (RT-PCR) were enrolled in the study. Inpatient and outpatient COVID-19 participants were followed up by regular visits or phone calls, and the recovery period was recorded.

Results

A total of 478 patients were enrolled. The mean age of patients was 54.11 ± 5.65 years, and 44.2% were female. The median time to recovery was 13.5 days (IQR: 9). Although in the bivariate analysis, multiple factors, including hypertension, fever, diabetes mellitus, gender, and admission location, significantly contributed to prolonging the recovery period, in multivariate analysis, only dyspnea had a significant association with this variable (p = 0.02, the adjusted OR of 2.05; 95% CI 1.12–3.75).

Conclusion

This study supports that dyspnea is a predictor of recovery time. It seems like optimal management of the comorbidities plays the most crucial role in recovery from COVID-19.
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Metadata
Title
Predictors of the prolonged recovery period in COVID-19 patients: a cross-sectional study
Authors
SeyedAhmad SeyedAlinaghi
Ladan Abbasian
Mohammad Solduzian
Niloofar Ayoobi Yazdi
Fatemeh Jafari
Alireza Adibimehr
Aazam Farahani
Arezoo Salami Khaneshan
Parvaneh Ebrahimi Alavijeh
Zahra Jahani
Elnaz Karimian
Zahra Ahmadinejad
Hossein Khalili
Arash Seifi
Fereshteh Ghiasvand
Sara Ghaderkhani
Mehrnaz Rasoolinejad
Publication date
01-12-2021
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2021
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/s40001-021-00513-x

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